1200-1205
A mini review on chemistry and biology of Holoptelea integrifolia Roxb. Planch (Ulmaceae)
Authors: Dinesh Kumar, Karunesh Kumar, Jyoti Gupta, Navita Bishnoi, Sunil Kumar

Number of views: 292
Holoptelea integrifolia Roxb. (Indian Elm) is a very useful and popular traditional medicinal
plant in India. During the last three decades, apart from the chemistry of plant compounds,
considerable progress regarding the biological activity and medicinal applications of Indian Elm
has been achieved. Ethno-medically, the leaves and stem bark of this plant have been used by
tribes as antiviral, antioxidant, antimicrobial, abortifacient preparations and in the management
of cancer. Recent studies on plant show that it has potential to fight against tumor and obesity
as well. Phytochemical investigation shows the presence of chemical constituents such as
terpenoids, alkaloids, glycosides, carbohydrates, steroids, sterols, saponins, tannins, proteins and
flavanoids. The isolated principles such as β-amyrin, β-sitosterol, holoptelin-A, holoptelin-B,
hederagenin, hexacosanol, β-D-glucose, friedelin, epifriedelin, 2-amino naphthoquinone,
1
,4-naphthalenedione, are considered as responsible for various activities. This review highlights
the traditional uses, reported biological/pharmacological activities, isolated compounds and
therapeutic applications of Holoptelea integrifolia which might be helpful for scientists and
researchers to find out new chemical entities responsible for its claimed traditional uses.