Jurnal Medical Brasovean

4

Authors: Alina Bisoc

Anthracycline-induced cardiotoxicity mechanisms are multiple and promoted by direct cardiotoxicity through oxidative “stress” induced by free oxygen radicals and by myocyte apoptosis. The cardiotoxic effects of anthracyclines are influenced by genetic profile, facilitating the intramyocardial increase of the iron ions and the “iron-mediated free radicals”, and the antineoplastic effectiveness can be reduced by the occurrence of anthracycline-induced cardiomyopathy

5

Authors: Petru Ifteni, Paula-Simina Petric, Ana Aliana Fodor, Liliana Rogozea, Andreea Teodorescu

The involuntary admission is a complex process that involves many people and services and it is surrounded by many controversies. The aim of this study is to highlight the clinical and therapeutic aspects of involuntary admission of patients in a psychiatric setting.

5

Authors: Magdalena Diaconuescu, Carmen Adella Sîrbu, Monica Marilena Ţânţu

In a hyperkapnic patient, the decision of orotracheal intubation and mechanical ventilation takes into account the benefits of the ventilator support, but also its drawbacks, since mechanical ventilation can last from a few days to weeks. Extubation of a patient is performed safely when he/she is ready to resume the spontaneous respiratory cycle, is conscious, cooperative, able to cough, and the hemodynamic parameters are stable. There must also be a multidisciplinary team to provide adequate nursing, an effective respiratory physiokinetotherapy. We will present the case of a man with unknown pathology who came in the Emergency Arrivals Unit with a very serious general state having respiratory insufficiency and a tendency to collapse, requiring orotracheal intubation and mechanical ventilation. After multiple investigations, interdisciplinary consultations and prolonged mechanical ventilation, broncho-pulmonary neoplasm was declared the main cause of general degradation.

6

Authors: Luigi G. Marceanu, Alexandru Covaciu, Elena Bobescu

In the group of balance disorders, vertigo (feeling of rotation/displacement) is the most common symptom. The next after vertigo, there is sensations of postural instability - generically described by patients as "dizziness". This symptomatology may be an alarm signal for the patient and for the physician, indicating the installation of a variety of disorders, both of the internal ear and of other organs and systems involved in the balance function. Due to the multitude of potential causes, the postural instability syndrome remains a very difficult to evaluate and diagnose pathology.

6

Authors: Cocuz Maria-Elena

Influenza, acute respiratory illness, very contagious by air, that can cause severe complications (especially respiratory) and death, can be prevented by non-specific measures and vaccination, recommended to all people, in particular to groups at risk for severe forms (children, pregnant women, elderly, people who have various chronic medical conditions). We performed a retrospective study, with the analysis of some epidemiological and clinical aspects of influenza cases in adults hospitalized in Clinical Infectious Diseases Hospital of Brasov during Dec. 2016-May 2017. There have been hospitalized 100 patients, 79% from the urban area, without a significant gender difference, with the highest frequency in January – 47% cases, 62% aged 18-45 years and 53% cases with influenza A virus. Respiratory damage was diagnosed at 76% of patients, dominated by interstitial pneumonia – 58% cases. Acute respiratory failure presented 23% of cases. Evolution was favourable in all cases. Influenza vaccination prevents illness and hospitalization

7

Authors: Teodora Mathe; Liliana Rogozea

Good communication between professionals and patients is often the key to quality health care. Disclosure truth regarding incurable disease is however a problem, many professionals disagree, feel vulnerable. Moreover in the case of children with life limiting illness for some professionals telling truth it becomes an extremely difficult task. The emotional charge is larger and the idea of incurable disease for children often contradicts the idea of meaning of life.

7

Authors: Curis Cecilia, Moroianu Lavinia Alexandra

General considerations: The therapeutic relationship fulfills a fundamental role in diagnostic acceptance. Methods: The study has been realized in the period 2008-2016, on the sample of 200 patients. This theory was confirmed by a mixed and prospective study, in line with the data in the medical literature. Results: Results were (globally) consistent with the results of similar studies. New aspects have also been highlighted regarding the diagnostic acceptance in relation to the therapeutic relationship in patient with psychosomatic disorders. The work hypothesis was confirmed by the results. Conclusions (on a single study test – no. 5): The therapeutic relationship quantified by the patient’s satisfaction index is in a relationship directly proportional to the degree of psychosomatic impairment.

7

Authors: Meda Romana Simu, Ioana Tosa, Anca Mesaros, Cristina Borzan

In daily dental practice we encounter children with poor oral hygiene and multiple decays. Starting from the premise that these situations occur due to lack of education in oro-dental health, the purpose of this study was to analyse the knowledge in oral hygiene of pupils in classes I to VIII. A cohort of 100 pupils with rural and urban origin was evaluated. We performed a descriptive observational study using a structured questionnaire of 20 items, questions with pre-formulated answers on visits to the dentist, oral hygiene notions and habits. The collected data were statistically processed. There were some significant differences between the two environments but the knowledge regarding oro-dental hygiene and the correct brushing techniques proved to be poor in both environments. The study indicates an acute necessity of consistent, systematic and long-term prevention programs, knowing that the child’s oral health supports the dento-periodontal status of the future adult.

8

Authors: Roxana Miclăuş, Liliana Rogozea, Adriana Sarah Nica, Nadinne Roman, Silviu Caloian, Cristina Mateescu

The paper debates the legal issues as basis of medical balneal activity in the late nineteen century and early twentieth century (before the First World War), also summarizing the dilemma of absence of specific balneal legislation and underlying the difficulties of medical practice in the context of lacks and legal contradictions inside the historical, legal and economical context of arising the new medical specialty of balneal and spa therapy. Regulations issued in the nineteenth century establish legal and administrative activity in bathing facilities, as follows: starting from two Civil Codes that subordinate health (Code Calimach in Moldavia and Caragea Code in Wallachia), through the Organic Regulations of 1832 and the Health Law of 1885, then the laws of management and operation of the Spa state's area (Law of 1886 and The Regulation of 1888). Other laws mark the end of the nineteenth century by discouraging initiative and private investment in resorts and spa facilities in Wallachia. Only in the last decades of the nineteenth century the state began to worry about preparing the legislative package and the adoption of organizational measures to promote and encourage the development balneology and climatology in our country. Early twentieth century marked the new balneal resorts, officialy recognition through legislation and the administrative and research structures of mineral resources, funded by credits (Law of Organising the Ministry of Trade and Industry passed by Parliament in March 1909, Law of Exploatation of Balneal State Area, passed in March 1909, The New Law of Health passed in December 1910) and by transferring the necessary logistic to research field (Romanian Geological Institute). While bringing a new breath and concern for legislative regulation of exploitation and use of mineral springs and natural factors resorts’ medical activity and the attitudes toward balneology in the early twentieth century is deeply marked of unfavorable and disadvantageous legal issues which will delay the transforming balneology in a medical activities conducted by specialized doctors and will delay the modernization of conservation, exploitation and management of mineral springs, balneology development and balneal research in early Romania.