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Socio-demographic characteristics of patients with schizophrenia and metabolic syndrome
Authors: Petru Ifteni, conf.univ.dr. Victoria Burtea, A. Teodorescu
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BACKGROUND. Metabolic syndrome associates central obesity, hypertension, dyslipidaemia and glucose intolerance is highly prevalent in individuals with schizophrenia. The prevalence of MS varies across countries and psychiatric treatments.
AIMS. The study has proposed the creation of a prospective study of the prevalence of metabolic syndrome in a group of patients with schizophrenia diagnosed according to DSM IV criteria, hospitalized in Psychiatry and Neurology - Brasov in January - December 2012.
METHODS. Each hospitalized patient with schizophrenia was evaluated in terms of the presence or absence of metabolic syndrome components after signing informed consent. This resulted in a group of 50 patients who were analyzed in terms of socio-demographic variables (gender, age, residence, marital status, educational status, professional status, use of nicotine, alcohol), psychopathological variables (type of schizophrenia period of development of disease onset, age at onset, current antipsychotic medication), history family history (diabetes, obesity, hypertension, dyslipidemia) and treatment history.
RESULTS. The prevalence of metabolic syndrome was higher in women (60%), aged between 22 and 60 years (mean age 43.8 years). History-Side are significant in 30% of patients with metabolic syndrome group was highly significant (p <0.05) when associated at least 2 metabolic risk factors in first degree relatives 1.
CONCLUSIONS. Prevalence of metabolic syndrome in patients with schizophrenia in the general group studied was relatively high. Among patients with metabolic syndrome was the most common triad association between elevated BP, the waist circumference and increased serum triglycerides. The most common combination of two risk factors for metabolic syndrome was increased waist circumference with increased serum triglycerides.