Acta Biomedica Brasiliensia

1 - 9

Authors: Chaline Barbosa de Laia NUNES1, Kimberly Marques ARRUDA1* & Théa Nobre PEREIRA1

A Vacina do Papilomavírus Humano (HPV) é o mais novo método de prevenção ao câncer de colo de útero oferecido pelo Ministério da Saúde (MS) no Brasil, a partir de 2014. Esta vacina oferece cobertura contra os quatro sorotipos de HPV mais comumente relacionados ao desenvolvimento de câncer, entretanto tem sido alvo de muitos questionamentos sobre sua eficácia. Este trabalho tem por objetivo descrever as características da Vacina HPV quadrivalente oferecida gratuitamente através do Sistema Único de Saúde (SUS) e apresentar dados publicados sobre sua eficácia. Foram utilizados livros e também artigos de bases de dados como Bireme, Lilacs, PubMed e Scielo com os seguintes descritores: HPV; vacina HPV; vacina quadrivalente; câncer de colo de útero, e seus equivalentes em língua inglesa. Tal vacina demonstrou elevados valores de eficácia (97 a 100%) na prevenção de lesões precursoras do câncer cervical resultando em um excelente método de prevenção à essa doença.

21 - 27

Authors: Arandir de Souza CARVALHO1,2*, Dinart Rocha FILHO2, Afonso Lunz ROBERTO3, Daniel Martins Cândido da SILVA4 & Gisele Aparecida FÓFANO5,6

A situação de saúde no Brasil se caracteriza por uma transição demográfica acelerada e por uma situação epidemiológica de tripla carga de doenças. Uma população em processo rápido de envelhecimento significa um crescente incremento relativo das condições crônicas, em especial das doenças crônicas, porque elas afetam mais os segmentos de maior idade (MENDES, 2012). No Brasil são cerca de 17 milhões de portadores de hipertensão arterial, 35% da população de 40 anos e mais. E esse número é crescente; seu aparecimento está cada vez mais precoce e estima-se que cerca de 4% das crianças e adolescentes também sejam portadoras (BRASIL, 2006a). A Hipertensão arterial é definida pela persistência dos níveis da pressão arterial sistólica maior ou igual a 140 mmHg e pressão arterial diastólica maior ou igual a 90mmHg. É considerada uma patologia que provoca sérias consequências no sistema cardiovascular e renovascular devido aos seus sinais e sintomas, muitas das vezes, serem silenciosos (MINAS GERAIS, 2006). “A Hipertensão arterial sistêmica tem alta prevalência e baixas taxas de controle, é considerada um dos principais fatores de risco (FR) modificáveis e um dos mais importantes problemas de saúde pública.” (SOCIEDADE BRASILEIRA DE CARDIOLOGIA, 2010). Segundo o Ministério da Saúde (2009), o envelhecimento da população aliado ao sedentarismo, inatividade física, hábitos de vida poucos saudáveis, são os grandes responsáveis pelo aumento da incidência e prevalência de doenças crônicas não transmissíveis (DCNT), entre elas, a hipertensão arterial, conhecida como a “inimiga silenciosa” por ser na maior parte do seu curso assintomática.

35 - 44

Authors: Luíza Figueiras BICALHO1*, Margarete Zacarias Tostes de ALMEIDA1, Márcia Reis GUIMARÃES2, João Romário Gomes SILVA1 & Fábio FULLY1

O presente estudo tem como mote a Síndrome de Irlen,uma disfunção perceptual que está relacionada com a fonte de luz, luminância, intensidade, comprimento de onda e contraste de cor, afeta o foco esuscitado portador uma constante adaptação das distorções,causando fadiga e desconforto mediante a uma leitura lenta, ineficiente, pobre em compreensão, além da inabilidade de uma leitura contínua, com tensão, podendo também estar associado com problemas de grafia. Objetivou-se sistematizar o conhecimento acerca da Síndrome de Irlen e o comprometimento da aprendizagem em nível de graduação, num estudo de caso, cujo objeto de pesquisa versará sobre o desenvolvimento de aprendizagem de uma estudante do curso de graduação em Medicina, campus V- Itaperuna/RJ. Pesquisa qualitativa norteada pelo Estudo de caso Único, cujo aporte teórico ancorou-se em autores como Irlen; Lass(1989), entre outros. Concluiu-se que, embora seja uma condição clínica subdiagnosticada pelos principais profissionais envolvidos na área específica da Educação Médica, todos os pacientes diagnosticados com a síndrome, que são tratados de forma adequada, ou com o overlay ou com os filtros espectrais, apresentam melhorias significativas em relação a suas queixas principais, sendo que a grande maioria relata melhora em algum grau de outra condição específica da síndrome que o próprio paciente não se queixava antes do tratamento.

56 - 67

Authors: Carla Regina Oliveira RAGGI1 & Bianca Magnelli MANGIAVACCHI1*

A hipertensão arterial está entre as causas mais frequentes de óbitos registrados nos últimos anos no município de São José do Calçado, ES, sendo, possivelmente, responsável pela maior parte dos casos de incapacidade física e invalidez precoce, razões que fomentaram a elaboração deste trabalho. A população de estudo constitui-se por uma maioria de baixa renda, acima dos 50 anos, que possui doenças associadas à hipertensão, adotando um estilo de vida sedentário, caracterizado por uma alimentação inadequada, rica em sal e gorduras. Sendo assim pode-se concluir nesse trabalho que a presença de fatores dos riscos, de patologias associadas e a pouca informação sobre a hipertensão pode ser resultado da falta de acompanhamento adequado e, sobretudo, da falta de incentivo em programas de Educação em Saúde que contemplem a problemática e seus determinantes, o que poderá ser conseguido com o controle e prevenção da hipertensão arterial no município.

78 - 83

Authors: Sara NUSS1, Kiara de MEDEIROS1, Marília ALONSO1, Nídia GOMES & Luciana FUMIAN1*

Uma equipe multidisciplinar é aquela em que existem vários profissionais atendendo o mesmo paciente de maneira independente. Objetivo: Relatar o caso de uma paciente que está acamada por longa data, com 77anos de idade, com úlcera por pressão grau III, e a importância da abordagem multidisciplinar no que tange ao cuidado de pacientes com sequelas incapacitantes. Materiais e métodos: Este trabalho constitui-se de um relato de caso de uma paciente vítima de Acidente Vascular Cerebral, institucionalizada por longa data e desenvolvendo uma lesão dérmica. Tendo como base para reabilitação o delineamento de um plano terapêutico através de condutas e protocolos específicos estabelecidos e executados por uma equipe interdisciplinar. Resultados: foi possível evidenciar a remissão completa da ferida após um tempo total de doze meses de tratamento. Conclusão: o estímulo à relação interdisciplinar deverá ser vista como uma parceira na resolubilidade das complicações da saúde, assim como essencial ponto para o sucesso do trabalho considerando o perfil de cada cliente assistido.

91 - 100

Authors: Phalon de Sousa Galvão MULLER1, Lorena Fonseca da SILVA1, Cristiano Guilherme Alves de OLIVEIRA1 & Denise Aparecida da SILVA1

Introdução e objetivos: a regulamentação referente à venda de antibióticos foi introduzida visando limitar o seu uso abusivo. O objetivo da pesquisa foi avaliar a aceitação da população em relação a tais medidas. Metodologia: foi aplicado um questionário aos clientes de uma farmácia localizada na região central do município de Itaperuna de setembro de 2014 a fevereiro de 2015, com questões referentes ao uso de antibióticos e à legislação vigente sobre sua venda. Resultados e conclusões: Foram entrevistados 100 indivíduos de ambos os sexos com idade de 18 a 87 anos sendo 55% do sexo feminino e 45% do sexo masculino. Os resultados permitiram concluir que a maioria dos entrevistados têm conhecimento e concorda com a nova regulamentação acerca das vendas de antibióticos; quanto maior a idade menor o conhecimento da legislação; quanto maior o nível de escolaridade maior o conhecimento da legislação; quanto maior o nível socioeconômico maior a tentativa de compra de antibióticos sem prescrição; a procura por antibióticos é maior pelas mulheres até 37 anos de idade, à partir da qual a procura maior pelos antibióticos é no sexo masculino; as principais patologias que levam à procura de antibióticos são amigdalite seguida de infecção urinária e sinusite; algumas farmácias não seguem corretamente a legislação referente à venda de antibióticos.

1 - 14

Authors: Shaytner Campos Duarte, Dalcio Ricardo de Andrade, Eduardo Shimoda, Jorge Hernandez Fernandez, Marcelo Fanttini Polese, Manuel Vazquez Vidal Jr

Realizing the need for more clarification on the status of research on Fish Nutrition, this work aimed to do a bibliometric study, using the Scopus database, using the entries Fish Nutrition and Enzyme Activity, both in Brazil and worldwide. The results were presented stratified, showing the tendencies of publication in the specific knowledge area. The research in the Scopus database was performed on January 2012, taking into account the historical series from 1999 to 2010. The data obtained from the research were: number of publications per year or historic series, publication by author, by area, by journal, by institution, by country and the language of the publication. The analysis of the concentration was performed by the comparison of the number of publication of the 10 main contributors (countries, knowledge area, authors, institutions and journal) in relation to the total of publications from Scopus database. For a temporal analysis, were used exponential regression equations of the number of publications in relation to the year. The values of each variable were linearized by the application of the logarithm, by means that the equation’s angular coefficient indicates the rank of growth in a specific period. The research showed that publications in "Fish Nutrition" and "Enzyme activity" had significant growth in the last decade, once the growth rate in publications worldwide and in Brazil were 204.4 and 493.2 in "Fish Nutrition", respectively. Also, the growth rate of publications for "Enzyme activity" showed values of 157.9 and 292 for the world and Brazil. The analysis of these data suggests a continuous interest in the areas surveyed, with great potential for development of this kind of research, especially in Brazil.

25 - 30

Authors: Maynard Noleto Sales, Diego Carvalho Viana, Amilton Cesar dos Santos, Alanna Carla Faria Couto & Michel Santos Silva

Diabetes mellitus, a non-communicable disease that can affect men and women, can be classified as type I or type II. This disease is in the 4th position in numbers of deaths in Brazil, and therefore, involves attention, both from the government, as the patients and family. The aims of this study is describe the lifestyle in relation to diet, foot care and proper medication, and the point of view of patients with diabetes mellitus type II, on the importance of the practice of physical exercise, coordinated and programmed. We performed a study using Questionnaire of Self-Care Activities with Diabetes (QAD) and a second questionnaire with questions related to the importance of exercise for patients with diabetes mellitus type II. Questionnaires were applied in 20 patients with the disease (08 men and 12 women), living in the city of Palmas, Tocantins, Brazil. Result: We noticed that even with the recommendations of healthcare professionals, most patients with diabetes mellitus type 2 has not adapted verification of blood glucose, proper nutrition and foot care. Moreover, despite the interviewees know the importance of performing regular physical activity, we noticed that these do not know how much of weekly days in which they must get physical exercise in order to control the disease. Most interviewees adopt just walk as the physical activity, and we have not verified from the answers of patients, if they know what the most beneficial exercises to control this disease.

40 - 48

Authors: Felipe Gonçalves Pilta, Ricardo Augusto de Almeida & Flávio Buratti Gonçalves

The Development of automation for macroscopic identification of filamentous fungi is a device whose goal is to automate the process of identifying images efficiently, thus supporting the area of biomedicine. The system was powered with up to six plates that contain the samples to be analyzed. These samples will be in a magazine with vertical movement by an actuator driven by an inductive sensor in the presence of a plates. The actuador slides the magazine nameplate to the mat where a picture is taken, and then is analyzed by comparing it with a database os pre-selected images. Thereafter, the plate moves being deposited in a reservoir. This work has application in bio analysis laboratories: enhancing the quality os the analysis, improving accuracy, reducing time and errors of analysis and thus obtaining greater credibility within the market of biomedicine.

60 - 70

Authors: Altina silva Oliveira, Tiago Rodrigues Carvalho, Marta Duarte de Barros & Fábio Barbosa Batista

The present study aims to verify the process of production management of the university's pharmacy Universidade Iguaçu (UNIG) – Campus V, Itaperuna, Rio de Janeiro. There is the belief that planning production control is the essential tool for growth and solidification of masterful sector and it is perfectly possible to implement this plan within pharmacies. Methodological aspects related to planning and production control literature and its tools were discussed. Methodologically exploratory research, which was used in a focused interview to assess and understand the process of managing the university's pharmacy UNIG Itaperuna, RJ was performed. Preliminary results indicate that it does not use the planning and control of production processes. It was found that PCP may contribute to the quality production of medicines in Pharmacy University.

79 - 97

Authors: Maria Aparecida Aride Bertonceli, Nathália Bastos Lima & Franz Viana Borges

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which affect mainly the lungs, but can also occur at different organs. It is considered a public health problem which is aggravated by AIDS epidemic. The contributing factors for the tuberculosis permanence are the social inequality, few research investments for new treatments and vaccines, migratory flows, health system flaws and high levels of multi-drug resistant cases associated to HIV infection. The goal of this research was to evaluate the healthcare professionals knowledge of the municipality of Apiacá (ES) about the aspects related to tuberculosis (preventing, treatment and symptoms) and the needing to indentify active search activities, the detection, accompaniment and the treatment abandon levels reduction. To do that, it was also applied a questionnaire related to the theme for 30 healthcare professionals from that location. Despite of the studied population know some aspects of tuberculosis, still there are some fails in the tuberculosis control program in that location, possibly because of the lack of qualified human resources to combat the disease, generating function overloading among those healthcare professionals. Training better the capability of those workers is necessary to prevent the disease among the population, to detect tuberculosis precociously and treat it adequately. It is essential to create health education strategies to improve the population knowledge about preventing, transmission, treatment and cure of tuberculosis.

110 - 117

Authors: Ohanna Daher de Paula Felipe, Wálace Érick de Medeiros Moura, Silvani Barreto Assumpção Cardoso, Júlio Correa de Campos, André Nascimento Monteiro & Juliano da Silva França

The objective of this research was to analyze the effects of therapeutic ultrasound 3MHz associated a phonophoresis in reducing edema fibro geloid in the abdominal region. For such a search was performed experimental the type case study. The study was conducted with a female patient of 30 years, with frame of EGF grade 1 and 2 in the abdominal region. A type-specific assessment for edema fibro geloid and photographic records were used. The patient underwent 20 treatment sessions accomplished out 3 times a week with duration 24 minutes ultrasound. The US protocol used in this study was frequency of 3 MHz, with an intensity of 0.6 W / cm ², continuous mode, phonophoresis associated with a coupling substance, in gel form, compound by arnica, seaweed, Asian centella, Chestnut of India, horsetail, ivy, mate, bitter orange, green tea, ginger and L-carnitine manufactured by Buona vita cosmetics. At the end of treatment was observed an improvesEGF, improvement in skin appearance and patient satisfaction with the results. With this, concluded that the associated ultrasound phonophoresis may be beneficial in the treatment of EGF, proving to be an effective resource in the aspect of it.

1 - 11

Authors: Marcella Costa RADAEL, Eduardo SHIMODA, Shaytner Campos DUARTE, Dalcio Ricardo de ANDRADE, Heloisa Alves GUIMARÃES & Manuel Vazquez VIDAL JR

Reproduction is a fundamental part of life being and studies related to fish reproduction have been much accessed. The aim of this study was to perform a bibliometric analysis in intend to identify trends in this kind of publication. During June 2013, were performed searches on Scopus Database, using the term “fish reproduction”, being compiled and presented information related to the number of publications per year, number of publications by country, publications by author, by journal, by institution and most used keywords. Based on the study, it was possible to obtain the following results: Brazil occupies a highlight position in number of papers, being that the Brazilian participation compared to worldwide publishing production is having an exponential increase; in Brazil, there is a high concentration of articles when concerning the top 10 authors and institutions. The present study allows verifying that the term “fish reproduction” has been focused by many scientific papers, being that in Brazil there is a special research effort related to this subject, especially in the last few years. The main contribution concerns to the use of bibliometric methods to describe the growth and concentration of researches in the area of fishfarm and reproduction.

21 - 29

Authors: Ione Ayala Gualandi de OLIVEIRA, Margareth Crisóstomo PORTELA & Claudia Cristina de Aguiar PEREIRA

Hepatitis C is a serious public health problem, affecting approximately 170 million people worldwide, with substantial morbidity and mortality. The clinical diagnosis is accidental, whereas the infection is often asymptomatic. The laboratory diagnosis is critical to establish active disease. There are different tests available for diagnostic confirmation of the virus, including serological and molecular techniques. The objective of this research was to present the different modalities available today molecular techniques for confirmation of the disease, considering its accuracy and different prices. We were built algorithms for the simulation of scenarios performed simulations from the data accuracy of technologies and of the prices of the same to the Brazilian health care system. The study showed that the quantitative molecular tests, although more expensive, can be a less costly alternative, considering the handling of patient with regard to laboratory diagnosis, resulting in a choice of importance to managers in the incorporation of new technologies in the Canadian health system.

45 - 55

Authors: Raniele Ramalho de SOUZA, Sara Fonte Boa de OLIVEIRA, Fernanda Castro MANHÃES, Karla Rangel RIBEIRO & Eduardo SHIMODA

The nursing care systematization (NCS) is considered as a process that is part of the nursing process with several advantages cited in the literature. However, there is the impression that is rarely used, which imply a number of issues for patients. The aim of this study is therefore to assess the perceptions of nurses in the southern region of Espirito Santo and northern/northwest regions of Rio de Janeiro about NCS. To this end, 30 nurses of mentioned regions were ask, through semi-structured questionnaire, about the importance and use of NCS, as well as its implications and limitations were interviewed. As a result, it was found that nurses have knowledge about NCS and consider it important, but conclude that the same is not widely used, despite the negative implications of this low utilization. Main causes cited are lack of human resources and support institutions.

71 - 79

Authors: Simone Aparecida Matos de SOUZA & Denise Aparecida da SILVA

An exploratory qualitative and quantitative search was conducted during the period May-August 2013 in the Clinical Laboratory of the Clinical Hospital in the city of Itaperuna , RJ. The objective was to analyze the profile of patients under anticoagulant treatment and demonstrate the potential variations in the values of International Normalized Relation (INR) compared to reference values and the frequency of such examinations. It was applied a questionnaire shortly before the blood collection , establishing itself as inclusion criteria the use of anticoagulants. The results indicated a total of 45 patients under treatment with anticoagulants, being 32 female and 13 male. The majority of patients was receiving treatment with the oral anticoagulant, the warfarin, and had more than 50 years old. The mean of INR values was within limits considered safe, but more than half of the patients had INR  2.0 and most patients under treatment with anticoagulants does not perform evaluation of INR frequently.

1 - 11

Authors: Cícero Cardoso Valle Filho & Denise Aparecida da Silva

An research was carried out in order to evaluate the potential increase in non steroidal anti-inflammatory drugs (NSAIDs) partially selective for COX-2 sold during the period of July of 2009 to June of 2011 in a drugstore located in the Itaperuna city, state of Rio de Janeiro. During the study period the total of partially selective for COX-2 NSAIDs sold was equivalent to 802, among which 59.85% were of nimesulide, 5.74% of etodolac and 34.41% of meloxicam. In the first semester the total dispensation of partially selective NSAIDs was equivalent to 92, in the second semester the total dispensation was equivalent to 159, in the third the total dispensation was 219 partially selective for COX-2 NSAIDs and in the fourth semester were dispensated the total of 332. The results showed greater dispensation of drugs of this class in April of 2011 and nimesulide, meloxicam and etodolac were more sold in the last semester of study. According to the methodology used can be concluded that the dispensation of partially selective NSAIDs is growing every year and that nimesulide has the highest rate of growth, the principal indication of nimesulide has been for children, the months corresponding to the period of winter presents a higher dispensation of partially selective for COX-2 NSAIDs.

21 - 34

Authors: Geyse Santos & Montcharles da Silva Pontes

In recent years, increasing concerns about toxicity residues in agricultural products have stimulated an increased interest in new agricultural strategies. While considering new strategies, the question arises if homeopathic preparations could be of use in plants. Homeopathy was born as an experimental discipline, and, generally, plants are able to react to homeopathic substances. In this paper, we conduct an up-to-date review of the existing in literature on Brazilian basic research in homeopathy applied in plants and agroecosystems to raise the profiles of Brazilian publications, according QUALIS methods and H index of Journals. The results of this research are useful not only for those who are interested in the homeopathy itself, but also to analyze the expanding that through experiments attending mainly agroecological production, aimed at improving on the level of publications.

52 - 57

Authors: Geraldo Pereira Junior & Paula de Sousa Barbosa

This study aimed to determine the prevalence of endoparasites in stray dogs in the city of Manaus-AM. Stool samples were collected from 80 stray dogs in municipal fairs areas: North, East, South and Center of Manaus-Am. To diagnose fecal samples were used methods and Willis-Mollay flotation in saturated sucrose. All samples were positive for the presence of endoparasites, with Ancylostoma sp. the most prevalent (85%). The study demonstrated the high spread of intestinal parasites of stray dogs in the city of Manaus.

72 - 80

Authors: Juliano Barreto, Anders Teixeira Gomes, Monica Aparecida Teixeira Muruci & Nickerson José Zanon de Abreu

This study aimed at evaluating the effectiveness of the application of HACCP (Hazard Analysis and Critical Control Points) as a quality tool in the prevention of contamination by molds and yeasts, in a production process in an industrial sweet milk. This tool that principle was developed by the private sector, is currently part of the legislation of many countries. For this production was evaluated data from a dairy manufactures of Bom Jesus do Itabapoana, northwest of the state Rio de Janeiro, which processes an average of fifty thousand liters of milk per day. We performed a literature search regarding HACCP and its implementation as a quality tool that ensured the theoretical support. The study shows the effectiveness of this quality tool in the prevention of contamination by molds and yeasts, for it was carried out a qualitative and quantitative analysis on the records of microbiological monitoring of the dairy.

90 - 105

Authors: Regiane Inácio Bittencourt de Oliveira, Anders Teixeira Gomes & Denise Aparecida da Silva

The present study deals with an qualitative and quantitative work of conducted between March to August 2013 with the aim of evaluating the practice of self-medication by clients of a community pharmacy in the city of Muriahe - MG. Data were evaluated through a questionnaire administered to clients and it was related to age, self-medication, care and pharmaceutical care. A total of 100 questionnaires were used and divided into two groups of 50 guests each, a group of feminine sex clients and another one of masculine sex clients. According the results, clients aged between 20-40 years perform the self-medication more frequently (60%) being anti-inflammatory drugs (NSAIDs), the myorelaxant/spasmolytics and anti-ulcer the most widely used drugs in both groups to self-medication. Symptoms most often cited as a justification of self-medication in both groups included headache, followed by fever for the feminine group and cold for the masculine group. The counter clerks are sources for self-medication, and among the clients, 31 of feminine sex and 33 of masculine sex said that they store medicines at home. It was also observed that the majority in both groups, claims to know the potential benefits and/or risks of selfmedication, but unaware of potential drug interactions, as well as the majority do not read the package insert that accompanies the medication.

114 - 123

Authors: Raphael Laiber Bonadiman; Renata Laiber Bonadiman; Samuel Laiber Bonadiman; Denise Aparecida da Silva

An survey was conducted from the evaluation of drug prescriptions presented during two months in a basic pharmacy of the municipality of Itapemirim, Espírito Santo. The main objective was to verify the errors found in prescriptions in order to provide data for further guidance to health professionals. A total of 3536 prescriptions were evaluated, among which in 1653 there were errors (46.75%). The errors most frequently encountered were related to prescription according to the DCB (52.99%) and the stamp of the prescriber (27.22%). Other errors have included erasure (19.60%), drug concentration (14.03%), dosage (12.95%), illegibility (10.16%), date (9.80%), patient identification (8.95%), administration route (7.99%) and identification of the prescriber (0.66%). Most of the drugs were dispensed in simple recipe and was performed by physicians. Among the total of 9235 prescription drugs, 3270 (35.41%) were not met due to lack of medicines with the basic component. According to the methodology applied can be concluded that more than 50% of professionals do not realize their prescriptions according to DCB, and also other errors are frequent such as the lack of the stamp of the prescriber and erasures in prescriptions, which can result in dispensing errors and consequent medication errors. Furthermore, the results showed greater demand for drugs in relation to their availability in the public healthcare centers.