INTERRELATION OF THE MICROELEMENT, IMMUNE HOMEOSTASIS AND INDICATORS OF THE CONDITION OF THE INTESTINE MICROBIOCENOSIS IN CHILDREN WITH BRONCHIAL ASTHMA
Authors: Smiyan O. I., Kurganska V. O., Sichnenko P. I., Bynda T. P., Romaniuk O. K., Gorbas V. A., Vasylieva O. G.
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The influence of quantitative and qualitative composition of intestinal microflora on the state of mineral metabolism and the immune system was study in the 128 children with asthma. The correlation between the number of representatives of the intestinal microbiota, bioelements and indicators of immune status were studied. The dependence of immune parameters, micronutrient content and quality of intestinal microflora detected in children with asthma that manifested significant imbalance of immune and microelement’s homeostasis. The results give reason to consider overgrowth in school age children with asthma as one of the factors that support secondary immunodeficiency, impaired microelement’s metabolism. The reducing of the number of lacto-and bifidobacterias, E. coli colonies and growth of opportunistic microorganisms, staphylococci and fungi have a significant impact on changes in the immune system and the microelement’s composition, supports allergic inflammation in the body of the child, even in remission, which is important and promising in terms of finding new ways of optimal treatment of childhood asthma.