46-53
Influence of ligand structure on anticancer and antioxidant properties of rhenium cluster compounds
Authors: I. V. Leus, E. D. Skorik, N. V. Beztsinna, N. I. Shtemenko
Number of views: 402
Under the model growth of T8 Guerin’s carcinoma in rats we studied the anticancer activity of the system rhenium-platinum, which includes cis-dicarboxylates of rhenium (III) with different alkyl ligands, erythrocytes number and its morphological structure, erythrocytic stability, blood haemoglobin concentration, catalase activity and concentration of TBA-active products in the rats blood plasma. The renium-platinum system had considerable antioxidat effect and prevented the growth of tumour, that was maximal for a compound with the pivalate ligand.