Jurnal Medical Brasovean

3

Authors: Bianca Popovici

Essential hypertension, one of the most frequent di seases all over the world, in adulthood, became important concern also in children and adolescents. Blood pressure values in childhood are predictive for blood pressure values as adult and also for future car diovascular disease. Although, the mechanisms are not very well known, we know quite well the risk factor s which are involved in essential hypertension and we also know that prevention is more efficient than treatment.

3

Authors: Laz ă r L. Onisâi

The importance of the kidney within the organism is given by the fact that it is the most richly vascularised organ; the renal arteries are the biggest br anches of the aorta as compared to the volume of the organ it irrigates. Researchers come up against problems related to the constitution of the kidney every time they try to interpret the variations of the renal structures and esp ecially of its vessels, the latter representing the most important structure and the mostly studied ever since the earliest times. The present paper aims to present the macroscopic an atomic aspect of the terminal branches of the renal artery.

3

Authors: Anca-Laura Gabor

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice, accounting for approximately one third of hospitalizations for cardi ac rhythm disturbances. AF is highly prevalent and growing. AF is associated with an increased long-term risk of stroke, heart failure, and all-cause mortality. Management of patients with AF involves 3 objectives: rate control, prevention of thromboembolism, and correction of the rhythm disturbance. The new paradi gm include rate and rhythm control, mostly normal sinus rhythm if it’s possible a nd appropriate anticoagulation accord ing to the risk of bleeding.

4

Authors: Claudia Gavriş , Mariana Rădoi , Emanuil Gheorghiţă, Maria Anghel ,Roxana Bârsăşteanu , Petru Gorgon, Liliana Duca, G. Pamfil., G.I. Pandele

The present paper describes a flow cytometric method for assay of platelet activation and provides information important in identifying and differentia ting thrombogenic states in patients with primary antiphospholipid syndrome (SAFP). Objectives:to evaluate the significance of platelet ac tivation markers for the evolution with venous and arterial recurrent thrombosis in patients (pts). with SAFP. Methods: 14 pts. with SAFP diagnosed according to revised Sapporo classification for APS criteria, mean age .47.87(18-74) years,7 women and 7men, were followed 24 month for the evolution with recurrent thrombosis. The expression of platelet activation markers CD62P (Pselectin) and CD40L were assesed using standardised flow cytometric method (Becton Dickins on) at baseline and after 12 months. Statistics: The results are shown as mean ± SD. Paired t tests were used for statistical comparisons. Results: No significant correlation was observed between expression of platelet activation markers CD62P (Pselectin) and CD40L in patients with histor y of recurrent thrombosis and SAFP patients without recurrent thrombosis. One single patient from six pts. had a acute trombotic event during follow-up expressed markers of platelet activation. Conclusions: Platelet activation markers in flow-citometry did not correlated with reccurent thrombosis and acute thrombosis in pts. with SAFP.

4

Authors: Milena Adina Man, Dana Alexandrescu

Idiopathic pulmonary fibrosis (IPF) remains the most common of the idiopathic interstitial pneumonias and portends a poor prognosis. The number of deaths related to IPF is nearly 14 times greater than those from asbestosis. The disease course in IPF is variable, with many patients remaining stable for long periods of time while a significant proportion expe rience exacerbations leading to respiratory failure and death. Traditional IPF pharmacotherapy has emphasized immunosuppression, but corticotherapy can have severe side effects.

5

Authors: Lia Ildiko Coman, Janos Szederjesi, Leonard Azamfirei

The bispectral index measures the electric activity of the brain and provides information about the depth of the hypnosis and is useful for the prevention of the intra-anaesthetic awakening. Although it was at first enthusiastically received, in the last years this type of monitoring is seen as quite controversial due to discrepancies of the data regarding the sensitivity of the method. The study analyses the limits and deficiencies of this type of intra-anaesthetic monitoring.

5

Authors: V. Tzaneva¹ , dr. H. Kolev, dr. G. Arabadjiev, D.L.Dumitrascu

The purpose of the study was to determine the anxiet y levels in relatives of the affected with swine flu patients, the hospital staff and the students during the flu epidemy. Method: The anxiety was measured by the State-Tr ait Anxiety Inventory (STAI) questionnaire in 38 medical students, 31 relatives and 34 nurses and physic ians for the period November – December 2009. RESULTS: It was determined that a higher level of a nxiety was related with the negative information from media. Conclusion: High level of anxiety is understandable due to the inv asive information. Anxiety after the compaign, suggests the need for support with positive media examples throughout the epidemy.

5

Authors: Ileana Muntean , Lucian Boja

This review describes the case of a 73 years old woman, diagnosed with a tumor located in the orbit, lacrimal gland foseta, intracranial invasive, suggestively looking for adenoid cystic carcinoma of lacrimal gland, in which pathoanatomy examination of the operators piece diagnosed was craniopharyngioma.

7

Authors: Marius Irimie, Alexandru Oanţă, Alexandru Tătaru

High prevalence, but also the constant increasing in cidence of dermatophytic infections of the skin and its appendages in whole the world, induced a continuous interest in studying the ethyology, the development of new diagnostic methods and the improvement of their therapy. The risk of dermatophytosis is determined both by pathogenic properties of fungal strains and host characteristics: age, dietary habits, social conditions, inherited and ac quired immunological deficiencies (A IDS, tumors, diabetes and other endocrinopathies). The relationship between diabetes and dermatophyte infections is controversial: some authors sustain and others negate a correlation between the prevalence of these infections and blood levels of glucose. A correlation was found between frequency of dermatophytosis and levels of glycosylated haemoglobin only in patients with diabetes mellitus type 2. Trichophyton rubrum and Trichophyton mentagrophytes are the most common pathogens responsible for more than 90% of infections. Therapeutic regimens for dermatophytosis in patients with diabetes are similar to those for nondiabetic patients. Treatment options include oral antifungal agents, topical therapy and combination therapy. Oral antifungal agents are effective therapy but have been associated with systematic adverse events and drug interactions. The use of these agents may be limited due to abnormal laboratory parameters and concomitant interacting drug therapy in the diabetic population especially in those patients with significant multiple comorbidities.