Jurnal Medical Brasovean

3

Authors: Ligia Grad

Candida belongs to normal human micro-flora; it is the main infection source. Thus, it can be transmitted by contact with skin and secretions, by inject ion with not sterile needles and by dissemination of endogenous infection. By using antibiotics, we can grow th e hope of life up to ten years. It is also increased the resistance and the infection with fungi. The preventive-care and the curative measures can make efficient all medical efforts.

3

Authors: Maria-Elena Cocuz , Roxana Miclăuş , Mihaela Idomir

Novel pandemic flu AH1N1 does not present until now great different with seasonal flu concerning the mechanism of transmission human to human, clinical aspects and therapy of uncomplicated cases. The aim was the study of some laboratory analyses in AH 1N1 flu namely the biological inflammatory syndrome. It is a retrospective study, made on analysis of data from medical papers of patients admitted with AH1N1 flu in Infectious Diseases Hospital from Braşov. The results of our study demonstrate that in pandemic AH1N1 flu does not exists specific alterations of laboratory parametriums. In this situation aetiology setting requires virological tests.

4

Authors: Alexandrescu Dana ,Barbu Elena, Alexandru Bălescu, Man Milena,Raţiu-Duma Bogdan, Fildan Ariadna Petronela , Dante ş Elena, Arghir Oana

Allergic and infectious diseases which have obstructive ventilatory dysfunction determine modifications that appear at spirometry, which is an important way to identify and correlate the respiratory involvement and symptomatology. The porpoise of this paperwork is to correlate and identify the spirometry modifications between allergy/atopy and bronchial asthma , bronchitis, recurrent wheezing. Childhood allergic ground obstructive respiratory disorders are a freq uent respiratory pathology with sometimes unknown and/or unidentifyable triggers and make it challenging.

5

Authors: Nicoleta Taus, Laurian Taus, Mirela Donea, Monica Potrovi ţ a, Daniela Marinescu, Ligia Neica

Evidence of oxidative stress in horses has been described in reports dealing with intense and endurance exercise. Oxidation provides energy for main tenance of cellular integrity and functions. Most of the consumed oxygen forms carbon dioxide and water; however, 1 to 2% of the oxygen is not completely reduced and forms reactive oxygen species. In thoroughbred race horses, as in other species subj ected to physical activity, there is a rise in the imbalance between free radical production and antioxidant agents which leads to oxidative stress. This stress may produce damage in several bio-molecules creating me tabolic alterations affectin g physical performance. The aim of this study was to find possible relationship s between physical exercise and oxidative stress in trained horses.

5

Authors: Claudia Gavri ş C. , Mariana Rădoi, Emanoil Gheorghiţă E. , Anghel M. , Liliana Duca , Pamfil.G.,G.I. Pandele

Objectives: to evaluate the significance of Pselectin and sCD40L levels for the evolution with venous and arterial recurrent thrombosis in patients (pts.) with antiphospholipid syndrome (APS) secondary to systemic lupus erythematosus (LES). Methods: 20 pts. with APS secondary to LES di agnosed according to revised Sapporo classification for APS criteria, mean age 47.87 (18-74) years, 16 women and 4 men were followed 24 months for the evolution with recurrent thrombosis. Serum IgG or Ig M anticardiolipin antibodies (aCL), serum Pselectin and sCD40L (R&D Minneapolis, SUA) levels were asse ssed using standardised ELISAs method at baseline and after 12 months. Statistics:t test/ANOVA, logistic regression. Results: APS pts. with a history of thrombosis had higher Pselectin levels then did APS pts. without a history of thrombosis (256.63±145.79 versus 121.85±101.47ng/dl; p=0.04). Pts. with APS showed higher sCD40L levels than did subjects without a history of thrombosis (15402.29±15290.62 versus 9508.99±6164.03ng/dl; p=0.34). No significant correlatio n were observed between aCL levels in patients with recurrent thrombosis and AP S patients without reccurent thrombosis (194.25±237.59 versus 52.57±10.64UPL; p=0.13). Conclusions: Pselectin seems to be a serologic test most likely to be correlated with reccurent thrombosis in pts. with APS associated with LES.

5

Authors: Roxana Miclăuş , Maria Elena Cocuz, Mihaela Andronic, Gabriela Cristescu

The endometrial cancer continues to represent an important problem of menopause women’s health. It is the first cause of morbidity among genital cancer in USA and the second genital cancer in Romania after the cervical cancer. The article presents the results of a retrospective study developed on three years (01.01.2006 – 31.12.2008) on the patients diagnosed with endometrial cancer following the specific parameters as: incidence, environmental distribution (town/country), age, parity, co morbidity, dominant symptoms, therapeutic procedures, staging, major intra surgical complications and association of specific oncology treatment.

6

Authors: Valeriu. Bronescu ,Luigi Mărceanu

Upper airway obstruction and obstructive sleep apnoea in children (OSAS) is recognized as a common health problem in daily ENT practice. If its di agnosis and treatment are delayed, the consequences of sleep-disordered breathing to children’s growin g can be severe. Obstructive sleep apnoea syndrome (OSAS) is a very important and prevalent disease, whic h is associated with a poor quality of life in many children patients. Understanding of mechanisms of obstructive sleep apnoea and its associated syndromes (obstruction syndrome) makes the possibility of use surgic al treatments like adenotonsilectomy. This one can resolve a lot of upper airway obstructions and improve the disordered breathing in children, and increasing of life’s quality. In this study 158 patients children, with mild to moderate OSAS, were evaluated using the Calgary SAQLI questionnaire applied before and four weeks after treatment with an adenotonsilectomy. Conclusion: The systematic use of the adenotonsilectom y indicates a clear improvement in the global quality of life as well as in the symptoms of patients with OSAS.

6

Authors: Alina Dobroş , Marius Irimie

Behcet’s disease is a chronic, inflammatory multisystemic condition of unknown aetiology. It is clinically characterized by recurrent orogenital ulcera tions and skin eruptions, ocular manifestations, arthri- tis, vasculitis and in some cases neurological and large vessel involvement. Aetiology has not been defined, but genetic, environmental, viral, bacterial and im munological factors have been proposed as causative agents. We present the case of a 32-year-old male patient that was admitted in our hospital with fever, recur- rent oral and scrotal aphthous ulcerations, erythemato us painful nodules on his calves and forearms, arthral- gias and superficial migratory thrombophlebitis on the lower limbs. Papulo-pustular lesions were developing on the venous punction on the right forearm. Laboratory investigations showed an elevated ESR and leuko- cytosis, and the histopatologic examination of a cutaneous biopsy specimen revealed a perivascular neutro- philic inflammatory infiltrate on the upper dermis. Di agnosis of Behcet’s disease was made. Treatment con- sisted in oral prednisone 1 mg/kgc/day, dapsone 100 mg/day and pentoxiphylline 400 mg/day associated with topical antiseptics and anaesthetics for oral ulcera tions, followed by fever remission after 48 hours and oral ulcerations healing after one week.

7

Authors: Dana Badău , Fatma Arslan, Gevat Cecilia

All the recent researches show that the rate of obesity in children is rising, requiring awareness of the need for physical activity, for a balanced and healt hy diet, and for reducing the danger represented by the modern informatics media inducing a sedentary living. Health threatening risks, embodied in numerous complications (heart failure, hypertension, exertion dyspnoea, sleep apnoea, atherosclerosis, etc.) have a strong impact (including financial) on the health syst em. We think that practicing any form of physical activity may result in maintaining normal somatic indices, and avoids overweight or obesity.