Journal of Indian System of Medicine

2

Authors: SRPKethamakka

The Idea of “Make in India” hit the minds of all groups including investors and intellectuals. The new spirit, drive and directions has fueled the Ayurveda fraternity through dynamic “3D” Prime Minister Shri Narendraji Modi in 2014. The “Made in India” Ayurveda has to be well shaped in forth coming days under the proficient guidance of him and independent responsible minister of AYUSH, Shri Shripad Yesso Naik. For them theAyurveda is a way of life and it can free a person from disease and ensure patient remains healthy.

4

Authors: Rohit Gokarn, Dhiraj Rajput ,P Bedarkar, Galib, BJ Patgiri, PK Prajapati

Safety and efficacy of metallic preparations has always been a concern. There has been timely wakeup calls by various incomplete researches. Although constant efforts have been undertaken by research scholars in various institutes but these were not highlighted due to lack of awareness regarding publications. This is a sensuous endeavor to bring those attempts in front of scientific community. Toxicity of various metallic preparations like Naga Bhasma, Tamra Bhasma etc and some commonly used Kupipakwa preparations that include Sameerapannaga Rasa, Rasamanikya, Rasakarpura and Rasasindhura has been studied to evaluate safety and were found to be safe for clinical use at therapeutic dose.

4

Authors: Shyam L. Bhutada , Sachin G. Khedikar

Ayurveda has a long history of serving humanity for centuries through their intellectual knowledge and experience. As the other sciences grew and developed in 19 century, in this period other health science was relegated to the secondary position. In order to mainstream the practice of traditional and alternative system of medicines in rural community and through various National programs government of India is making endeavors since decades. Multiple laws and Acts were amended for adequate functioning of Governing council and the systems too. CCIM, ISM&H, AYUSH, CCRAS, ICMR, CSIR etc. are also introduced to promote extensive regulations and Researches in Ayurveda. Well known Golden Triangle Initiative (GTP) of AYUSH, CSIR & ICMR is recently functioning to validate Ayurvedic Products. So GOI is taking tremendous endeavor to mainstreamAyurveda in National heath and making it feasible to adopt globally as a medical system.

5

Authors: Santosh M. Doifode, Mohan Lal Jaiswal

Mootrashmari (Urolithiasis) remains a significant health problem in the adult population till date. Ethylene glycol induced hypercalciuria and hyperoxaluria model was used to assess the antiurolithiatic activity of Parnabeeja in male albino rats. The serum and histopathological results clearly revealed the antiurolithiatic activity of fresh juice of leaves of Parnabeeja particularly of calcium oxalate origin. The study suggested that Parnabeeja (Bryophyllum pinnata) protects the rats from Mootrashmari induced by ethylene glycol.

5

Authors: Renu Bharat Rathi

Fluorosis is the accumulation of excessive fluorides in the body which produces toxic effects. It is a commonest public problem, endemic in 15 states of India. It causes the enamel to become abnormally porous and weak. It also injures bones and may create anaemia by decreasing red blood cell production as it is difficult to completely cure the effects of dental fluorosis. No detail description has been found in Ayurveda regarding fluorosis which resemble with Shyavdanta in terms of similar causes, features, treatment and prognosis. Hence an attempt has been made to correlate both. This article aims to review the studies conducted on fluorosis with Ayurvedic treatment approach. Shyavdant has Pitta, Vata dominance and is mentioned as incurable by Sushrut when it progresses to whole body. Different modalities for local action like Pratisaran (application), Gandush (oil pulling), Kawal (gargling) to generalized Shodhan(eliminative) procedures, Shamanopchar (curative) medications mentioned for Shyavdant can be used for Fluorosis which starts from teeth and spreads to all over the body. Proper awareness is important to prevent its serious hazards as there is no permanent treatment once manifested in chronic form. It can be concluded on the basis of scientific review that Ayurvedic interventions of Shyavdant can be applied with other treatment modalities to treat endemic fluorosis which needs urgent, economical and effective intervention.

7

Authors: Abhishek Y. Patalia1, Preeti Pandya2

There are ample of collections for effective management of diseases in octapertite Ayurveda. The geometrical rise of demand for indigenous medicines, maintaining quality standards is the need of hour in present era. Absence of reference standards for compound formulations is a hindrance on the way towards standardization. The present study was aimed for experimenting preliminary Pharmacognostical and analytical profile of Triphaladi Avaleha. Study included preparation of Triphaladi Avaleha using pre authenticated raw drugs following all SOPs. Later Triphaladi Avaleha was subjected to Pharmacognostical and physicochemical analysis as per standard protocols. The final observations were systematically observed and recorded. Organoleptic features of Triphaladi Avaleha were within the standard range as per mention in standard texts. pH of 5% aqueous solution of Avaleha observed acidic in nature. Water soluble extractive was 82% w/w while solubility in alcohol was 91.8% w/w. Qualitatively the metabolites like, carbohydrate, steroid, saponin glycoside, flavonoid, alkaloid, tannins & phenolic compounds were found positive. Total sugar was 89.57%. Artificial Invert Sugar test for Honey was negative. Chromatographic evaluation gave a preliminary fingerprint of the formulation with appropriate solvent system in which 7 spots in long UV, 2 in short UV while after spraying 4 spots were observed. This may shows the presence of certain definite constituents in Triphaladi Avaleha. The quality of Triphaladi Avaleha can be ascertained by a cascade of Pharmacognostical and physicochemical screening for the findings in accordance with the observations of the present study. It was found that the formulation meets the required standards of an Avaleha at a preliminary level. The results of this study may be used as the reference standard in further research undertakings of its kind.

8

Authors: Sachin G. Khedikar, Mukund P. Erande

Genetics or genesis is the study of genes, heredity and variation in living organisms. The word genetics is derived from the Ancient Greek word genetikos meaning 'genitive', 'generative' or 'origin'. It intersects frequently with many of the life sciences and is strongly linked with the study of information systems. Modern embryology is greatly advanced in this field and describes each aspect about formation of Embryo & its development as a full term neonate with the help of Karyotyping. But the main objective of Garbhasharir described by Ayurvedic compendia is Suprajanan. And this makes the difference between Ayurved and Modern embryology because modern science only deals with structural teratogenesity of bodily organs while Ayurveda states about Structural, Physical and Mental status of a Foetus after its birth. There are several references of Garbhasharir which are quoted in Brihattrayee and their commentaries as well as in different Ayurveda texts that need to be interpreted in proper way to make them applicable for our science and society too. The concepts of Ayurveda genetic theory are beautifully described in various chapters of Sharirsthana of Samhita. The Abiogenesis described by Sushruta is one of best in Ayurveda literature. Almost all the topics about genesis are explained in Ayurveda compendia, the need is to comprehend this knowledge on the basis of present theory of Genetics.