Journal of Clinical Medicine of Kazakhstan

J Clin Med Kaz 2014; 3(33):8-12

Authors: Gunay Akbarova

It is presented an overview of the results of own studies in 39 settlements of Mugan, Shirvan, Ganja and Lenkoran-Kazakh economic regions of Azerbaijan during the period since 2005 to 2013 in this article. It was diagnosed the types of congenital and hereditary abnormalities, installed options of inheritance and frequency of their distribution by means of biochemical, hematological and molecular-genetic methods. The additional analysis by Reverse Dott-Blot Hybridization StripAssay and Big DyeTM Terminator DNA methods were hold in ambiguous clinical and laboratory results. The obtained results will make the basis of nation-wide register of congenital and hereditary diseases and will help in the differential diagnosis and treatment.

J Clin Med Kaz 2014; 3(33):17-21

Authors: Nelya Bissenova, Aigerim Yergaliyeva

The aim of this study was to analyses etiological structure from sputum of patients with progressive respiratory infections. Materials and methods. The sputum of hospitalized patients diagnosed with progressive respiratory infection during 2009-2013 was included to the prospective bacteriological study. Initial seeding material conducted a quantitative method on nutrient medium according to guidelines. The identification of isolates and antibiotic susceptibility testing were performed by microbiological analyzer Microtax, MiniApi and Vitek 2-Compact. The etiological factor was defined at a concentration of 106 and above. The results were subjected to statistical analysis. We determined averages, an averages error (m), Students test, a confidence interval (p). The probability of null hypothesis did not exceed 0.05 (p<0.05). Results. A total of 838 strains (43 species) were obtained from sputum of patients with progressive respiratory infections during 2009-2013. Streptococcus pneumoniae was determined in 337 (40.2%) strains, Moraxella catarrhalis – 17.0%, Streptococcus viridans – 12.1%, Streptococcus pyogenes – 6.3%, Staphylococcus aureus – 4.4%, Pseudomonas aeruginosa – 2.1% of total isolates. Conclusions. Streptococcus pneumoniae and Moraxella catarrhalis were the most frequently pathogens (40.2% and 17.0% respectively) from sputum of patients with progressive respiratory infections in our region.

J Clin Med Kaz 2014; 3(33):29-31

Authors: Ilknur Sahin, Ilknur Albayrak, Fatih Pektas, Sevket Arslan, Ali Yavuz Karahan, Adem Kucuk

Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterized by recurrent attacks of fever and serositis. Limited data suggest that the prevalence of sacroiliitis is increased in patients with FMF. Ankylosing spondylitis (AS) is a common inflammatory rheumatic disease characterized by inflammation of the axial joints, peripheral oligoarthritis, and enthesitis. Symptoms related to back pain should be investigated thoroughly in order to diagnose AS and distinguish symptoms related to it from FMF. We presented a 46 year old man who diagnosed FMF and AS.

J Clin Med Kaz 2014; 3(33):34-38

Authors: Arystan Seidalin, Adilzhan Albazarov, Rahim Tojiboyev, Timur Sarsengaliyev, Vladimir Dikolayev, Aidos Yerpashov

This message is clinical report of rare case of traumatic false aneurism of a descending thoracic aorta as a result of blunt trauma and aneurism of abdomen aorta and right iliac artery caused by injury of the right hip with formation of an arterio-venous fistula. Patient has been traumatized in a car accident. However, injury of thoracic and abdomen aorta were found much later (in 22 years) when there were symptoms of heart failure. In our clinic the patient was delivered "on a stretcher" with the expressed decompensation of heart function.

J Clin Med Kaz 2014; 3(33):41-43

Authors: Yerkebulan Burkitbayev

The purpose of this article was to consider various scenarios of realization of a strategic paradigm, and, first of all, from the point of view of probability of approach of the most adverse probable scenario conditions. This Article considers the key parameters and characteristics of the most significant risks from external and internal environment of JSC “National Medical Holding” by SWOT method. It allowed to give a structured description of the situation at JSC “National Medical Holding” and to give an initial assessment of the current situation.

J Clin Med Kaz 2014; 3(33):47-48

Authors: А.K. Segizbayeva, S.А. Shaimerdenov, V.S. Rakhmetova

Complex approach of the Center for Hepatology of Astana city to diagnosis and treatment of chronic viral hepatitis is presented in this material.