Варненски медицински форум (Varna Medical Forum)

13-17

Authors: Emil Kanchev,Georgi Kobakov,Kiril Kirov,Daniel Yankov,Petya Koleva, Snezhana Vicheva,Daniel Kostov,Nikolay Georgiev,Zdravko Dimitrov, Yordan Borisov

Recently, pathological expression of epidermal growth factor receptor (EGFR) is increasingly used in the diagnosis of various epidermal tumours. The aim of this study is to analyze the role of EGFR in comparison to p53 as a prognostic marker in patients with colon cancer who undergo surgical treatment. Two types of immunohistochemical examinations (for EGFR and p53) have been performed in 120 patients with colon cancer histologically verified by using of hematoxylin-eosin staining. Our results clearly demonstrate that EGFR expression is present in 18 patients (in 15% of the cases). It occurs much more often in the patient with TNM stage II and especially in those with TNM stage III and relatively more frequently in the patients aged between 51 and 70 years and presenting with a moderately differentiated tumour. Besides, this expression immediately relates to a recurrence of the disease and worsened clinical course. There exists a correlation between the enhanced expression of EGFR and that of p53. Because of the small sample, our results are not statistically significant. EGFR can serve as an independent prognostic factor and indicator of more common recurrences of the disease, worse quality of life and poorer prognosis in colon cancer patients. Further intensive collaboration between coloproctologists and pathologists is needed to improve the individualized surgical behaviour in such patients.

25-29

Authors: Biserka Pacholova,Strashimir Genev

The article presents the opportunities of e-h ealth telematics and telemedicine in the context of European eHealth initiatives. The practical application of digitalization in the field of diagnostic imaging in the creation of a regional telemedicineimaging centre in Dobrich Region is considered. The reasons for establishing the centre facing the negative health and demographic indicators, poor infrastructure, remoteness to hospitals and insufficient number of specialists in diagnostic imaging and radiologic technologists are presented. The information is systematized according to the already implemented and currently functioning systems worldwide and could meet the medical standards of communication. Several benefits for the region are highlighted such as improving the access of population to medical imaging aid that is characterized by the required timeliness, continuity and quality, ensuring equi table patients’ medical service as well as positive health and socio-economic impact.

35-39

Authors: Alexandar Stoyanov,Krasimira Nenova,Kiril Nenov

The patients with chronic renal failure (CRF) on chronic haemodialysis (CHD) should strictly adhere to the prescribed therapeutic regimens and physician’s guidelines. Otherwise the results from this long-lasting treatment are often unfavourable. The aim of the present study was to reveal the opinion of CRF patients on CHD about their attitude towards their continuous treatment. Forty patients, 21 males and 19 females, at the mean age of 50,48±14,90 years and a mean duration of CHD of 5,82±4,11 years were examined. They filled-in anonymous questionnaire containing 26 items devoted to their observation of the necessary therapeutic and dietary regimens. The longer CHD duration influenced negatively on patient’s compliance. However, such patients tended to observe more strictly the time for haemodialysis prescribed by the physician. Patient’s compliance depended on the educational level, too. Therefore, an extraordinarily important physician’s task was the provision to the patients of adequate information about their disease and its treatment.

47-52

Authors: Svetlana Geogrieva, Radoslava Dimitrova, Gergana Angelova-Popova

A child with disability is a severe problem for both parents and physicians. There are different degrees of disability leading to delay of physical and mental development. There is no perspective for a considerable improvement of the health status in a small group of children. Thus they need a specialized social support system because of their predisposition to hypotrophy. In this study, an inquiry investigation of medical staff engaged with specialized care for disabled children with hypotrophy was carried out. Some opportunities for hypotrophy prevention in the children with disabilities in ‘Faith, Hope and Love’ Home for Medical and Social Care for Children of the town of Bourgas, one of the few institutions in this field in Bulgaria, were revealed and discussed.