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SENSITIVITY OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS EXTRACTED FROM PATIENTS WITH SUPPURATIVE-INFLAMMATORY PROCESSES OF VARIOUS LOCALIZATION TO NEW FLUOREN COMPOUNDS
Authors: Rostyslav Pavliy, Svetlana Pavliy
Number of views: 635
Authors have investigated the sensitivity of methicillin-resistant Staphylococcus aureus extracted from patients with supurrative-inflammatory processes of various localizations to widely used drugs and to newly synthesized compounds of fluoren derivatives. The strains of staphylococci are most susceptible to fluoroquinolones (78,3-84,4%), cephalosporins (78,3-84%) and aminoglycosides 68,4-84,61%). Sensitivity of S. aureus to macropenes was negligible. The relatively high activity against the isolated strains of S. aureus has been shown by new derivatives of fluorene-Fl4, P6, P7 (63,0-70,79%). This is very important for their further study in order to develop new antimicrobial drugs.