European Journal of Medicine. Series B

4-11

Authors: Maricar Joy T. Andres, Milagros L. Borabo

The objective of the study is to know the essential components of Aesthetic Dentistry that will be a basis for prototype Outcomes-based training modules. Using a 5-point Likert scale, the researcher-made questionnaire assessed the different elements of Aesthetic Dentistry which are needed in the designing of the training module, the manner of presentation and the form of assessment that were needed in the training module. Statistical tools that were used for the study are percentage, frequency, weighted mean and standard deviation. The information gathered from the respondents was relevant in the development of a Prototype Outcomes-based Training Modules in Aesthetic Dentistry.

18-23

Authors: Rustambek Matmurodov, Oybek Turgunkhujaev, Khanifa Khalimova

Objective: To clarify clinical features of sleep disorders in patients with Parkinson’s disease (PD) and their effect on cognitive function and emotional-personal sphere. Material and methods: The study involved 62 patients with PD (33 men and 29 women) mean age 47.8+7.1 years. The control group consisted of 20 patients without Parkinsonism matching by age and sex. The diagnosis of PD was established by criteria A.Hughes. Patients underwent an extended neuropsychological study with qualitative and quantitative analysis. To determine cognitive disorders, we used neuropsychological tests. Results: 49 patients (79,3%) had sleep disorders. In the structure of sleep disorders: 29 (59.2%) patients had insomnia and 11 (22.4%) patients – parasomnia and 9 (18.4%) - hypersomnia. In a control group, numbers were 4.5 times less. The analysis showed that the structure of sleep disorders correlates with the form of PD. So, insomnia is more rapidly met in akinetic-rigid form (55.5%), whereas hypersomnia is presented in mixed form. Patients with insomnia present 35% of predement cognitive impairment and 34% of dementia (66.7% of mild degree dementia and 33.3% moderate dementia severity). Whereas, in patients with hypersomnia 35% of predement cognitive impairment, 60% of dementia (54.6% and 45.4%) were observed. Among patients with permanent drowsiness 32.4% of predement cognitive impairment and 58.4% of dementia (44.8% and 55.2%) were diagnosed. Dementia (65.4%) was observed more in patients with sudden sleep (42,8% and 57.2%). Conclusion: sleep and wakefulness disorders depend not only on the severity of motor symptoms, but also depend on the emotional and cognitive state.

34-43

Authors: Mihaela Posea, Andreea Dragomir, Emilia Rusu, Raluca Nan, Ramona Dragut, Horatiu Popescu, Florentina Stoicescu, Ileana Teodoru, Anca Hancu, Marilena Stoian, Gabriela Radulian

Background and Aims- To evaluate the impact of nutritional intervention on vitamins and minerals from intake food and anthropometric parameters at overweight and obese patients. Material and methods- To a sample of 40 overweight and obese patients we evaluated the nutritional content of food intake (kilocalories, macro and micronutrients). We also measured anthropometric parameters like weight, body mass index, body fat, percent of body fat, abdominal circumference and arterial tension. Results- After the nutritional intervention, overweight and obese patients had significantly lower level of intake carbohydrates (P=.018), lipids (P=.002), B1 vitamin (P<.001), B3 vitamin (P=.02) and E vitamin (P=.016). There is a significantly increased level of proteins (P<.001). Regarding the minerals, we found that the intake levels of following‘s decreased: sodium (P<.001), magnesium (P=.006), zinc (P=.035), copper (P=.002), manganese (P<.001). Phosphorus is the only mineral of which the intake level increased significantly (P<.001). All the anthropometric parameters decreased significantly: weight (P<.001), body mass index (P<.001), body fat (P<.001), percent of body fat (P<.001), abdominal circumference (P<0.001), systolic arterial tension (P<.001), diastolic arterial tension (P=.002). Conclusions- All the patients had imbalanced intake of vitamins and minerals both before and after intervention. There is a significant improved on anthropometric measures after nutritional intervention. We need to promote healthy lifestyle changes to prevent the risks associated with obesity.

54-59

Authors: Gulnora A. Rozikhodjaeva, Zakhro A. Usmanovа

The levels of matrix metalloproteinase-9 (MMP-9) and its tissue inhibitor (TIMP-1) in serum, and the concentration of Zn in the serum, hair and carotid atherosclerotic plaques were examined. The relationships zinc-dependent endopeptidases as biomarkers instability of atherosclerotic plaques and zinc in patients with carotid atherosclerosis were studied. The results contribute to the selection of patients at high risk for cardiovascular events.