International journal of dental and medical specialty

2-5

Authors: I. N. Ikhajiangbe Happy1, D. N. Ezejindu2, N. Ezeokafor Emmanuel1

Aims: The aim of this study is to compare the effect of bitter leaf (Vernonia Amygdalina) and glibenclamide in the treatment of diabetes in Alloxan-induced diabetic albino wistar rats. Materials and Methods: A total of 24 adult albino rats were used for the study. The rats were grouped into three groups of eight animals per group. Group A received 0.5 ml of distilled water and served as the control. Group B received 10 mg/kg/body weight of glibenclamide. Group C received 100 mg/kg/ body weight of bitter leaf extract. Effect of bitter leaf and glibenclamide were observed at every 2 days for up to 2 weeks. Results: The result showed that the extract caused a decrease in blood glucose level on the fourth day but this was not statistically signifi cant. Also, glibenclamide caused a decrease in the blood glucose level on the third day; this decrease was not statistically signifi cant but slightly signifi cant on the fourth day. On the sixth day, the extract caused a slightly signifi cant decrease but when compared with the sixth day of glibenclamide, the decrease was very signifi cant. From the eight day to the fourteenth day, the decrease in the blood glucose levels for group B and C became very signifi cant. However, group C (glibenclamide) showed highly signifi cant decrease when compared with group B (extract). Glibenclamide showed signifi cant (p<0.05 or p<0.01) decrease in mean blood glucose level from day 8 to till end (day 14) as compared to bitter leaf extract. Conclusion: The work suggests that glibenclamide has a more potent hypoglycemic effect in alloxan-induced diabetic wistar rats when compared with the extract and may be more effective in the treatment of diabetics.

10-13

Authors: Chaithra Kalkur, Anusha Rangare Lakshman, Mohammed Farhan, B. S. Kiran Kumar

Facial talon cusp (Dens evaginatus) is a very rare developmental anomaly of unclear etiology and significance can also be seen associated with some syndromes. Here the present report describes a 10-year-old female with facial talon cusp on mandibular permanent right central incisors. This rare anomaly requires careful dental and physical examination of the affected patient since its finding can be of clinical and genetic significance

18-20

Authors: Ruchika Khanna, Ruchit Khanna, P. M. L. Khanna

Cone beam computed tomography is a three-dimensional imaging modality and more accurate when compared to digital radiographs. The recent advancement in this technology has reduced the cost as well as the dose to the patients. The advanced software design and powerful computer system have permitted its use in dentistry. Its varied indications in practically all the branches of dentistry have made this progress all the more versatile. Through this review we have tried to highlight the basis of this technology, its advantages and applications, wherefore proving it to have an edge over the others

25-27

Authors: Ruchika Khanna, Ruchit Khanna

Osseous choristoma being a benign lesion is an entity rarely seen in the oral cavity. These are usually well-circumscribed proliferations of histologically normal tissue found in abnormal locations. They are usually composed of compact bone with harvesian systems. The etiology is considered to be developmental malformation or reactive. The most common site being the tongue and other sites being buccal mucosa as well. Through this article, we have tried to highlight various features that would aid in correct diagnosis and treatment planning of this rare lesion.