Modern Clinical Medicine Research

Number 3, 2018

4
Clinical Research Progress of Chinese Medicine in Treating Recurrent Respiratory Tract Infections in Children

Authors: Li Shufeng, Liu Jihua, Zhou Guoliang, Han Yangfei, Zhang Wei

Abstract

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Objective: To study the effect of traditional Chinese medicine ointment on recurrent respiratory infection in children in cold area, and the effect on the changes of trace elements and serum immune indexes. Methods: 100 cases of children with recurrent respiratory infection were selected from 06 months from 2016 to 06 months in 2017 in our hospital. All the children were divided into the observation group and the control group according to the random digital table method, with 50 cases in each group[3]. The children in the control group were treated with the standard treatment of anti inflammation of Western medicine[7], improving immunity and so on. The observation group was added with Jianpi moistening ointment on the basis of the standard treatment of Western medicine. After 2 weeks of continuous treatment[9], the clinical and laboratory indexes were compared between the 2 groups. Results: the total effective rate of treatment in the observation group was 90%, which was significantly higher than that of the control group (72%), and the difference between the 2 groups was statistically significant (P < 0.05). The serum immunologic level of the observation group and the control group were significantly improved after the treatment (P < 0.05), but the observation group was better than the control group (P < 0.05). Conclusion: traditional Chinese medicine ointment is effective in the treatment of recurrent respiratory infection in children, and it can significantly improve the serum immune level of children. It is worthy of clinical application[5].

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Antibacterial Activity of Medicinal Plants Used in the Management of HIV/AIDs Opportunistic Infections in Njeru Sub County, Buikwe District

Authors: Mustapha W. Shehu, Nafi’u Abdulkadir, Idris Bello, Abdulaziz Shehu, Sadiya A. Waziri

Abstract

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Infectious diseases such as skin infection, chronic cough, stomach infection, tuberculosis, diarrhoea, warts, herpes zoster and others were claimed to be treated using medicinal plants. The study was aimed at determining the antibacterial activity and determination of bioactive compound of some medicinal plants used in management of HIV/AIDS opportunistic infections. A total of six plants were subjected to phytochemical and three out of six were tested against bacterial pathogens. The aqueous extracts of plants leaves of Pseudospondias microcarpa (PM), Callistemon citrinus (CC) and Spathodea campanulata (SC) were tested against two bacterial pathogens namely: Staphylococcus aureus and Pseudomonas aeruginosa. The result revealed the presence of Saponins, Tannins, Anthracenosides and Steroid glycosides. Alkaloids, flavonoids and reducing sugars had narrow distribution among the species. The highest clear zones were found in PM against Staphylococcus aureus (21.18mm) followed by 20.07mm for CC and 19.03mm for PM against the same bacterium. For Pseudomonas aeruginosa 20.36mm, was recorded for PM, 21.3mm for CC and 20.16mm for Sc at different concentration. The antibiotic used as control revealed highest against all the tested bacteria. There was no significant difference between the bacterial activities of the extracts of the three plant species but it varied significantly across the different serial dilutions. Further studies should be conducted on phytochemical analysis to establish more active ingredients that may be used in the development of drugs by pharmaceutical companies.