The present study was investigated to establish the diuretic activity of methanolic extract of albizia lebbeck in ratsusing metabolic cages. The extract was administered toexperimental rats orally at dose of 200 and 400mg/kg and Frusemide (20 mg/kg) was used as standard. The parameters evaluated for diuretic activity were urine volume, concentration of sodium, potassium and chloride ions. The rats treated with methanolic extract of albizia lebbeckrevealed significant increase in the volume of urine, urinary concentration of Na+, K+and Cl-when compared to control group. Hence the plant has proved as diuretic.
We evaluated the hypoglycemic effects of methanol ratio extract of Clitoria ternatea leaves.The hypoglycemic effect was evaluated in alloxan induced diabetic rats. The extract ofClitoria ternateaalsosignificantly (P<0.001) reduced blood glucose level in alloxan induced diabetic rats twelve hours after administration
To study the antitumor effect of Kigelia africana. Antitumor activity of methanolic extracts of 100, 200 mg/kg of Kigelia Africanaleaves was evaluated against Ehrlich ascites carcinoma (EAC) tumor in mice. Acute and short-term toxicity studies were performed initially in order to ascertain the safety of methanolic extracts of Kigelia Africana. After 12 days of tumor inoculation, the extract was administered daily for 30 days. The effect of methanolic extracts of Kigelia Africanaon the growth of tumor, life span of EAC bearing hosts and simultaneous alterations in the haematological profile and histopathological profile were estimated. The methanolic extracts of Kigelia africanashowed decrease in tumor size, average bodyweight, mean survival time thereby increasing life span of EAC tumor bearing mice. Haematological profile reverted to more or less normal levels in extracts treated mice. Histopathology has minimal effects when compared but a significant variation is seen
The study aims to evaluate the nootropic and antibacterial capacity of methanolic of Piper trioicumRoxb. The antibacterial capacity of the extracts of Piper trioicum Roxb plant was estimated on gram positive and negative bacteria along withthe determination of the nootropic activity in these extracts using Wistar albino rats. The animals exposed to Scopolamine and treated with Piper trioicum Roxb extract (200 and 400 mg/kg) showed significantly (P<0.05 and P<0.01) decreasing in transfer latencyas compared to the negative control. Antibacterial activity of methanolic extract of Piper trioicum Roxb was more effective in Escherichia colithan other bacteria, but there wasno effect on Proteus mirabilis
Dalbergialatifoliais commonly called as “Beete and sitsal”. In the present study the cerebroprotective effect of methanolic extract of bark of Dalbergialatifolia(DL) was carried out against the global model of ischemia in rats. The animals were pre-treated with DL for a period of 1week (500 mg/kg) p.o. The animals were anaesthetized with thiopentone sodium (45mg/kg) and infarction was induced by Bilateral Common Carotid Artery Occlusion (BCCAO) for 30 mins with the help of suture threads, the knots were released with the help of slip knots. The animals were allowed to re-perfuse for a period of 48 Hrs. Then the animals were sacrificed brain was decapitated. Biochemical estimations for SOD, CAT, MPO & MDA and histological examinations were carried out.
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