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THE SYNTHESIS OF NEW SPIROLACTONES FROM SUBSTITUTED ISATINS
Authors: Natalia Sucman, Vsevolod Pogrebnoi, Mykola Obushak, Elena Melnic, Victor Kravtsov, Fliur Macaev
Number of views: 462
Described synthesis of 5-bromo substituted oxindoles linkages in spirocyclic butenolides exhibit relatively dependence of the structure-reactivity relationships of N-substituted isatines, dimethyl acetylenedicarboxylate and triphenylphoshine. The study of the stereochemistry of the atom C(2) of the spiro compounds was also unambiguously confirmed by single crystal X-ray analysis.