Journal of Intellectual Disability - Diagnosis and Treatment

113-116

Authors: D. Terziev, H. Manolova, S. Staykova, M. Hristova

The authors, child psychiatrists and clinical psychologists, conducting team assessment of children with developmental disabilities (including autism spectrum disorder) for more than two decades, present some important in their view issues and recommendations concerning planning and proceeding of assessment and post-assessment meetings with parents. It is essential to ensure not only an accurate assessment protocol and diagnosis, but also to "attune" to parents in order to facilitate their understanding and more positive use of assessment outcome results. Parents need further support to "survive" psychically the post - assessment period and to provide for adequate interventions for their child.

124-129

Authors: Mihaela Hristova, Harieta Manolova, Svetla Staykova, G Markova

Early and precise identification of neurodevelopmental disorders together with provision of adequate and timely interventions remain increasingly important tasks for multidisciplinary clinical teams. А central component in this process of comprehensive clinical evaluation is the assessment of children’s intellectual functioning. Intelligence test results represent a central component in the decision making process of determining a child’s future in terms of: qualification for special education, access to social welfare support, placement in therapeutic programs, etc. Clinical results yielded through the application of standardized intelligence assessment instruments (WISC, K-ABC, RPM), and especially the overall quantitative measure of cognitive ability (IQ) have become a central, and sometimes the only measure taken into consideration when determining a child’s level of functioning. Together with some distinct benefits, this practice places many children at risk of being underestimated and calls for revision and modification of standard assessment procedures. In line with these considerations, authors raise for discussion traditional approaches to diagnostics of intellectual functioning, highlighting some challenges, emerging from the constitutive particularities in the cognitive functioning of children with neurodevelopmental disorders. An attempt for identifying areas for further improvement alongside with research-informed recommendations for a contemporary, individualized and sensitive to the specifications of children with neurodevelopmental disorders assessment practice are outlined at the end of this paper. According to the authors’ opinion, exploration of the topic provides an important opportunity to advance the understanding of clinicians, primary healthcare professionals, educators and other professionals involved in supporting children with developmental deficits.

137-151

Authors: Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Md. Nasrullah, Ferdous Wahid, Mst. Marium Begum, Zubair Khalid Labu, Md. Sohanur Rahman, Md. Tanjir Islam, Md. Shah Amran, Mohamed M. Abdel-Daim

Neurochemistry refers to the chemical processes that occur in the brain and nervous system. This section of study determines how neurochemicals influence the network of neural operation. The brain transfers numerous chemical information via neurons to communicate. The main role of neurochemistry activities takes place in the brain, which allows it to perform numerous actions. Foundation of brain is a little bit different from man to man and several things can play a role in the levels of various neurotransmitters in the brain. It is supposed that differences in brain chemistry may accountable for a variety of behavioral disorders. A particular cell called neurons is the basis of brain. Neurotransmitters have the capability that it can trigger when ordered to do so, along with receptors for specific neurotransmitters. By sending messages with neurotransmitters to signal various cell activities, brain perform its functions. Neurotransmitter spreads chemical messages from neuron to neuron to broadcast certain work and thus it works. A neuron may accept many chemical messages, both positive and negative from the other neurons contiguous it. They are accountable to get the neuron to reply in different ways, or they may work combine to produce a certain effect. Since all of this occurs just within a split second, the neurotransmitter must be cleared away rapidly so that the same receptors can be activated again and again. Psychoactive drugs work by briefly influencing a man's neurochemistry, which thusly causes changes in a man's mind-set, cognition, perception and behavior. Neuropeptides are endogenous protein molecules that are utilized for neuronal signaling. These molecules exert more prolonged and diverse effects on behavior than neurotransmitters. Therefore the objective of this appraisal is to show study of the brain's chemical makeup especially neurotransmitters, psychopharmaceuticals, neuropeptides and their activities to nervous tissue.