Human leukocyte antigen (HLA) as part of the immune system has a role in the disease process. Genetic factors play an important role in susceptibility to vitiligo. Our aim in this study is to assess the relationship between HLA-DRB1 alleles frequency in Iraqi patients with vitiligo compared with a healthy control group using the PCR-SSOP method. The patient group consisted of forty Iraqi Arab Muslims patients with vitiligo that consulted the dermatological department in Al-Kindy teaching hospital from September 2013 to June 2015 were assessed for HLA genotyping for HLA-DRB1. A control group consisted of thirty healthy volunteers among the staff of AL-Kindy College of medicine that did not have vitiligo or family history of vitiligo. HLA genotyping for HLA-DRB1 was performed for each patient and for the control persons using PCR with sequence-specific-oligonucleotide primers. Results showed an increase in the frequency of HLA genotype DRB1* 07:0101 (P value= 0.026) and DRB1* 11:0101 (p-value = 0.016) in patients with vitiligo compared with healthy controls. In conclusions, our results suggest an association between HLA-DRB1* 07:0101 and DRB1* 11:0101 and susceptibility to vitiligo.
This study had as its aim, to examine health seeking behaviour among people suffering from cardiovascular disorders in the New Juaben Municipality in the Eastern Region of Ghana. Six hundred (600) participants, comprising male and female patients aged between 35-75 years and suffering from cardiovascular disorders for the past 12 months were selected used for the study. Cultural belief systems were found to significantly influence the health seeking behaviour of the people. Additionally, the perception of the aetiology of CVDs was socially constructed from a cultural point of view, which deviated from the orthodox views of disease causation. The finding of this study underscore the need for therapists and clinicians to adopt a culturally congruent approach to the provision of healthcare. This further calls for therapists to understand the cultural values and beliefs of the people in order to provide healthcare that would be acceptable to the people.
We describe a rare case of isolated congenital incus anomaly without other otologic anomalies in this case report. We detected this condition in an adult who presented with long standing, non progressive unilateral reduced hearing. Isolated congenital incus anomaly was identified incidentally during her visit for other otological problem. We discussed regarding the case and the important role of HRCT imaging as a single tool for diagnosing the anomaly without surgical exploration.
Osteoporosis with resultant fractures is a major global health problem with huge socio-economic implications for patients, families and healthcare services. Areal (2D bone mineral density (BMD) assessment is commonly used for predicting such fracture risk, but is unreliable, estimating only about 50% of bone strength. By contrast, computed tomography (CT) based techniques could provide improved metrics for estimating bone strength such as bone volume fraction (BVF; a 3D volumetric measure of mineralised bone), enabling cheap, safe and reliable strategies for clinical application, and to help divert resources to patients identified as most likely to benefit, meeting an unmet need.
Here we describe a novel method for measuring BVF at clinical-CT like low-resolution (550µm voxel size). Femoral heads (n=8) were micro-CT scanned ex-vivo. Micro-CT data were downgraded in resolution from 30µm to 550µm voxel size and BVF calculated at high and low resolution. Experimental mechanical testing was applied to measure ex vivo bone strength of samples. BVF measures collected at high-resolution showed high correlation (correlation coefficient r2=0.95) with low-resolution data. Low-resolution BVF metrics showed high correlation (r2=0.96) with calculated sample strength. These results demonstrate that measuring BVF at low resolution is feasible, which also predicts bone strength. Measures of BVF should be useful for clinically estimating bone strength and fracture risk. The method needs to be validated using clinical CT scans.
Background. Currently, EEG biofeedback (Neurofeedback) is used in the rehabilitation of children with brain damage with the symptoms of attention deficit disorder, hyperactivity and impulsivity. After treatment improvements were observed not only in the control of attention and impulsivity but also in voluntary and involuntary movements. The aim of the prospective clinical study was to measure the impact of EEG biofeedback on motor abilities of children with ADHD (Attention Deficit Hyperactivity Disorder) and compare the effectiveness of EEG biofeedback with classical rehabilitation. It was assumed that in children with ADHD in combination with central motor disorders EEG biofeedback therapy will strengthen not only the control of impulsivity and attention but also motor skills.
Material. The observed group consisted of 60 (N = 60) children with mild central motor disorders with ADHD. They were randomly assigned to either the EEG biofeedback group (N = 30, mean age 8.9 years) or the classical rehabilitation group (N = 30, mean age 8.5 years).
Methods. Both groups received thirty 30-45 minute sessions of training, at a frequency of 2-3 times a week. Pre-post assessment included testing of motor skills with PANESS test (Physical and Neurological Examination for Subtle Signs) for both groups and the EEG biofeedback group were assessed also for changes in impulse and attention control using CPT (Continuous Performance Test) test AX version and changes observed by parents using TLC Subjective Assessment (The Learning Curve, 2004).
Results. Achieved overall score of EEG biofeedback group was lower after therapy (Mdn = 24.00) than before therapy (Mdn = 55.00), T = 0.00, p <0.01, Z = -4.78, r = -0.62. Values of significance (Asymp.Sig. 2-tailed = 0.000) and effect size (effect size r = -0.62) indicate a statistical and factual significant positive effect of EEG biofeedback to improve overall motor skills (lower score is better).
Conclusion. EEG biofeedback therapy in children with ADHD improved control of attention, impulsivity and also improved motor skills. There were no significant differences in improvement of performance of timed movements between groups. Also, parents of children who received the EEG biofeedback therapy observed positive changes in behavior, learning and motor skills. Improvement in motor skills was significantly higher in the EEG Biofeedback group then in the classical rehabilitation group.
The potential use of zinc oxide and other metal oxide nanoparticles in biomedicine are gaining interest in the scientific and medical communities, largely due to the physical and chemical properties of these nanoparticles, therefore there is an urgent need to develop new classes of antimicrobial agents, and recent studies demonstrate that hold a considerable promises. Candida albicans were isolated from saliva of forty eight volunteers of both sexes their age range between 18-22 years and then purified and diagnosed according to morphological characteristic and biochemical tests. Different concentrations of ZnO NPs were prepared from the stock solution; all the experiments were conducted in vitro. Disk diffusion method was used to study the sensitivity of Candida albicans to different concentrations of zinc oxide nanoparticles in comparison to effect of de-ionized water. Candida albicans were sensitive to all cocentrations (0.01, 0.05, 0.1, 0.5, 1, 3 and 5.8 mg/ml) of the zinc oxide nanoparticles solution in comparison to de-ionized water, revealing a highly significant difference in all concentrations. This study revealed that zinc oxide nanoparticles were effective against Candida albicans.
The work deals with the analysis of the umbilical blood samples (120 samples) concerning the concentration of general protein and glucose as the main biological constants of newborns. There is no a reliable difference found between these indices while comparing groups with monocyesis and twin pregnancies. Possible correlation interrelation of certain biochemical indices in newborns during early postnatal period was examined (54 samples). In addition, changes of the examined biochemical indices were followed in the course of time in 19 newborns concerning the comparison of umbilical and venous blood.
This paper outlines the results on the antiviral and antimicrobial action of electrochemically activated NaCl solutions (anolyte/catholyte), produced in the anode and cathode chamber of the electrolitic cell, on classical swine fever (CSF) virus and a stain of E. coli DH5. It was found that the anolyte did not affect the growth of the cell culture PK-15; the viral growth during the infection of a cell monolayer with a cell culture virus was affected in the greatest degree by the anolyte in 1:1 dilution and less in other dilutions; whereas the viral growth at the infection of a cell suspension with the CSF virus was affected by the anolyte in dilution 1:1 in the greatest degree, and less by other dilutions; viral growth at the infection with a virus in suspension of the cell monolayer was affected by the anolyte in all dilutions. Unexpectedly, the stronger biocidal effect of the catholyte was observed when a strain of E. coli DH5 was treated by the anolyte and catholyte, respectively. In order to provide additional data about the antiviral activity of the electrochemically activated water and the distribution of H2O molecules according to the energies of hydrogen bonds, the non-equilibrium energy spectrum (NES) and differential non-equilibrium energy spectrum (DNES) of the anolyte and catholyte were measured.
Adolescence is the period of physical and psychological development from the onset of puberty to maturity. The World Health Organization defines an adolescent as a person between ages 10 and 19 years. A dramatic shift in thinking from concrete to abstract gives adolescents a whole new set of mental tools, to analyze situations logically in terms of cause and effect, appreciate hypothetical situations, evaluate alternatives, introspection, decision making and cognitive abilities. Adolescents experience intense physical, psychological changes as they make transition from childhood to adulthood. This period of transition is the most vulnerable time. Adolescents are at risk of developing behavioral problems like school failure and drop outs, substance abuse, delinquency and violence, sexually transmitted diseases, unwanted pregnancies, domestic violence, stress and depression and risk-taking behaviour. It is the responsibility of the society to utilize this period constructively through education, counseling, mass media, awareness programmes and address the reproductive health needs of adolescents. The present study analyzes the psychosocial risk status and knowledge of reproductive health in adolescents in Raipur city. The study recommends implementation of provisions by government to provide continuous education and economic security for adolescents. Programmes like age-appropriate reproductive health curriculum should be introduced in schools and colleges with counseling facilities at school and primary health care levels.
The upperlid colobomas are rare and usually associated with cryptophthalmos. The colobomas can either affect one or both eyes. They can be associated with life threatening syndromes which must always be looked out for. Our case however defied any of these associations.
Upper lid colobomas can lead to severe eyeball morbidities including blindness and must be attended to promptly either by conservative or surgical approaches depending on the size of the coloboma, the associated ocular morbidities and the age of the patient. The prognosis of the pathology is fairly good depending also on the surgeon’s expertise and time of presentation of the patient to the surgeon.
Modeling of sharp alcoholic intoxication induced animal 6 mg/kg of 50-70% ethanol by introduction. On this background studied effects of N-metilsitizin alkaloids and a desoxypeganin on ADP-induced aggregation of platelets and level of intracellular Ca2+ in the synaptosomes of a brain of rats. The obtained data render that the inhibiting effect of N-metilsitizin alkaloids and a desoxypeganin on ADP-induced aggregation of platelets is connected with oppression of a gain of cytoplasmatic concentration of Ca2+ from depot of platelets. Thus, N-metiltsitizin alkaloids and desoxypeganin block a gain of level of intracellular Ca2+ at the expense of increase in Ca2+ EPR pool, provoked by ethanol.
N-metiltsitizin doesn’t compete with a glutamate for a binding site. Perhaps, action of N-metiltsitizin is caused by interaction with ionic channels of NMDA receptors. The neuronal of the receptors involved in the mechanisms which are the cornerstone of AAS (including convulsive attacks) and effectively to stop to possibility of application of N-metilsitizin in regulation of dihydropyridine-sensitive calcic channels of the main subtypes them. It is shown that the possible competition between desoxypeganin and a glutamate for a site of binding of regulation of opening of ionic channels. Desoxypeganin directly doesn't affect calcic canals of a NMDA receptor. Perhaps, desoxypeganin like a glutamate causes overexcitation of NMDA receptors.
The aim of the present study was to determine the inotropic effect of 3'4'-dimethyl quercetin in the rat myocardium. Isometric tension forces were recorded using a force transducer (Type F30/Model D-79232; Hugo Sachs Elektronik, March-Hugstetten, Germany). 3',4'-dimethyl quercetin (10–100 µmol.L–1) exerts a positive inotropic effect in rat papillary muscles. Thus, inhibitor potential-dependent Са2+L-channels – nifedipine and inhibitor β-adrenoreceptor – propranolol has almost completely abolished the positive inotropic effects of 3',4'-dimethyl quercetin. Moreover, it was identified that the 3',4'-dimethyl quercetin depending on dose has increased quantity of the maximum velocity of force development, and the maximum velocity of papillary muscles relaxation. In conclusion, the present study demonstrates that 3',4'-dimethyl quercetin has showed a positive inotropic effect on rat papillary muscles that can be explained with the increase of [cAMP]in and may depend on increase of [Са2+]in. Furthermore, lusitropic effect of 3',4'-dimethyl quercetin can be increased in cAMP and inhibition of phosphodiesterase enzyme activates protein kinase A, which phosphorylates regulator protein activity Са2+-ATPase – phospholamban and RyRs.
Objective: This is a series of five cases of branchial anomalies which were diagnosed and treated in a span of six years in the Department of Otorhinolaryngology, Head & Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre (UKMMC). The main objective of this article is to highlight the use of endoscopic electrocautery in the management of branchial fistula. Case report: five cases were reported of the age group between 11 months old to 16 years who presented with an intermittent mucoid discharge from an external opening in the neck since birth and three cases were on the left side and the other two cases were bilateral fistula. Direct laryngoscopy under general anaesthesia was done as part of diagnostic and therapeutic management for the patients. Conclusion: Endoscopic electrocautery is a safe method and appears to be an effective alternative to open excision for branchial fistula.
The article presents the analysis of distribution of the group (according to AB0 system) and rhesus characteristics (according to anti-D system) in infants born to mothers with 0(I) Rh(+) blood group in Chernivtsi region (Ukraine) during the period of 2013-2014. The relationship of the umbilical bilirubin level and hemolytic disease of the newborn (HDN) (erythroblastosis fetalis), the necessity of its careful monitoring during the first day of life of a newborn, especially in case a baby belongs to a certain risk group, has been analyzed. The issue concerning probable HDN occurrence from mothers with А(II) Rh(+) blood group which is dominant in this region has been touched upon. The tasks for further work in this direction of ecopathophysiology in the areas of gene penetration have been assigned.
This paper presents the results of evaluation of possible biophysical methods and approaches for registering of various non-ionizing radiation (NIR) wave types of the human body in the optic and electromagnetic range. Various types of NIR (electromagnetic waves, infrared radiation, thermo radiation, bioluminiscence) emitted from the human body were reviewed. In particular the results on the spontaneous biophoton emission and the delayed luminescence from the human body were submitted along with infrared thermography (IRT) results. It was shown that 1 cm2 of skin generally emits 85 photons for 1 s. The intensity of biophoton emission ranges from 10−19 to 10−16 W/cm2 (approx. 1–1000 photons.cm-2.s-1). The specific bioluminiscence emission from part of the human thumb was detected as a spectrum of various colours with the method of Colour coronal spectral analysis on a device with an electrode made of polyethylene terephthalate (PET hostaphan) with applied electric voltage 15 kV, electric impulse duration 10 s, and electric current frequency 15 kHz. It was established that photons corresponding to a red color emission of visible electromagnetic spectrum have energy at 1,82 еV. The orange color of visible electromagnetic spectrum has energy at 2,05 eV, yellow – 2,14 eV, blue-green (cyan) – 2,43 eV, blue – 2,64 eV, and violet – 3,03 eV. The reliable result measurement norm was at E ≥ 2,53 eV, while the spectral range of the emission was within = 380–495±5 nm and = 570–750±5 nm. Also were estimated some important physical characteristics (energy of hydrogen bonds, wetting angle, surface tension) of water by the methods of non-equilibrium energy (NES) and differential non-equilibrium energy (DNES) spectrum of water, that helps understand in general how electromagnetic radiation interacts with water and establish the structural characteristics of water.
It is shown that the flavonoid pulikarin suppresses activity of an adenylate cyclase and reduces level intracellular [Ca2+], perhaps its effect is connected with inhibition of a gain of cytoplasmatic Ca2+ as at the expense of its entrance outside, and release from intracellular storages. Perhaps, oppression of fluorescence of membrane-bound Ca2+ is connected with inhibition of a pulikarin of release of calcium from intracellular depots. The inhibiting effect of a pulikarin on ADP-induced aggregation of platelets is connected with oppression of a gain of cytoplasmatic concentration of Ca2+ from depot of platelets.
Today is still insufficiently developed the methods of associative analysis of the medical, ecological and demographic parameters that would make it possible to determine the nature and extent of the influence of environmental factors on the population health, establish the basic laws of territorial differentiation of human diseases and to identify ways to optimize the environment. Identifying of such influence and its evaluation is the primary task of our study. The correlations between the environmental pollution of and level of morbidity prevalence of population of the Sumy region we obtained by the mathematical methods. In the analysis, we obtained the 143 pairs for which the correlation is significant at the level ≤0.05 and 50 pairs – for which the correlation is significant at the level ≤0.01, reflecting the most closely dependencies between prevalence of morbidity and the state of the environment. In the integrated form, the quality of drinking water is the most important factor, which closely correlated with the prevalence of diseases among the population of Sumy region. The influence of the ecological state of the air, including the gamma-background level, chemical and radioactive contamination of soils and crop production are also important, although less markedly.
Background: Pilot study tested re-education movements of upper extremity in children with hemiparesis syndrome and this study determined the effect of therapy on Armeo® equipment on movement and the ability to grip of upper extremity.
Methods: This Investigation consisted of twenty-three children with impaired upper extremity. They had twenty therapies in Armeo® equipment.
Results: After rehabilitation by equipment Armeo® the children achieved greater range of motions in the upper extremity which resulted in a higher average output score than the input score. Significant better results demonstrate the improvement in hand grip which resulted in higher average output score compared with the input score.
Conclusion: By the therapy in Armeo® equipment were achieved statistically significant results in improving manual activities of upper extremity, improvement the range of motions and also improvement of grip of paretic hand.
Ozone therapy and physiotherapy have been successfully used in obstetric practice. The paper summarizes the results of studies on the use of ozone therapy in the postoperative rehabilitation of gynecological patients operated on for female infertility of various origins. Biomechanisms systemic impact methods of ozone therapy on the human body to meet the requirements of the tactics of the impact on the etiopathogenic mechanisms of chronic inflammatory diseases of the pelvic organs and their complications. It is advisable to wider use of ozone therapy in the complex treatment standards gynecological patients. Postoperative rehabilitation, including ozone therapy, can have a significant impact on the clinical course of gynecological and extragenital pathology, pregnancy rate and its outcomes.
It has been performed complex examination of 50 school-aged children with bronchial asthma, which included a study of acetylation phenotype and a determination of deletions in the genes of glutathione-S-transferase (GSTM1 and GSTT1). The study has shown that in children with slow acetylation phenotype and the absence of deletions in genes GSTT1 and GSTM1 аssociates with poor control of the disease that requires increased anti-inflammatory therapy with an emphasis on higher "step". When using the ACT test for the assessment of asthma control often determined by the underestimation of their child's condition, indicating that about the need for the objectification of control of the disease with the help of spirographic method and subsequent correction of the basic therapy.
This article deals with questions of indicators of empathy display among future physiotherapists. Two methods were used to carry out the survey: V. Boiko empathy abilities questionnaire has been used to identify empathy components’ levels and I. Jusupov’s questionnaire of empathy level diagnostics has been used to identify empathy general level. The random sample size consists of 203 future physiotherapists. Participants comprised 119 students of 1st year and 84 students of 4th year full-time physiotherapy studies of Lithuanian Sports University.
It was determined that, in comparison with 1st year students of physiotherapy studies, general empathy level of 4th year students is higher. 1st and 4th year students of physiotherapy studies statistically significant differ according to these empathy components: cognitive empathy, affective empathy, attitudes towards empathy and empathic identification. Levels of these indicators of 4th year students are higher than those of 1st year students.
The efficacy of intratissue electrophoresis of antibacterial remedies was studied in multimodal treatment of 25 patients with burns of II-III stages with square from 7 % to 12 % of body's surface. It's determined that its using doesn't significantly influence the species composition of the burned wounds microflora but reliably decrease their microbial contamination and increase microorganisms' sensitivity to many antibiotics, improve course of wound healing process, stimulate reparative regeneration. This positively influence terms of burned surface elimination and generally treatment of burned patients.
The article analyzes the data in the literature the most common opportunistic infections in HIV-infected patients. The results of analysis of outpatients patients with HIV-infection are at a dispensary in the SI “Karaganda regional center for the prevention and control of AIDS”. Analyzed the prevalence of HIV-infection in the Republic of Kazakhstan, including Karaganda region for 2012-2013. The statistical data of deaths among people with AIDS in the Republic of Kazakhstan, mortality from tuberculosis HIV-infected patients in the Karaganda region.
In 110 patients with essential arterial hypertension (EAH) and overweight or abdominal obesity (AO) analyzed changes of peripheral hemodynamics and clinical signs under the influence of treatment, depending on genes’ polymorphism of the Angiotensin-converting enzyme (ACE, I/D) and the Peroxisome proliferator-activated receptor gamma-2 (PPAR-2, Pro12Ala). Under the combined treatment the "target" office blood pressure (BP) was achieved in 72.8 % subjects, the "adequate" reduction of BP – in 82.6 % patients. Depending on the EAH severity: "target" BP achieved in 100% patients with EAH I stage vs 76.2 % in person with EAH II stage (p=0.019) and 53.1 % – with EAH III stage (p=0.002). "Target" average daily BP24, daily BPd and nighttime BPn were achieved in 70.0 % patients (prevail those with EAH I-II stages by 47.1 % and 21.2 % (p=0.049), respectively, in I-allele carriers of ACE gene – by 17,9% (p=0.048) and Ala-allele carriers of PPAR-2 gene by 38.9 % (p=0.036).
Conducting a comprehensive clinical and paraclinical examinations of 53 children with severe asthma made it possible to establish the relative increase in the content of CD 22-lymphocytes (relative risk – 2.1 odds ratio - 3.8) and interleukin-5 (relative risk – 1.8 odds ratio - 3.4) in the serum of the patients with fast acetylatic status that reflected the implementation of the respiratory tract eosinophilic inflammation. In children with a slow acetylation phenotype severe asthma probably has been formed with the participation of other mechanisms that reflected the correlation of IL-8 with increased functional activity of blood neutrophils according to NBT-test (r = 0,5; p <0, 05) and bronchial hyperresponsiveness (r = 0,9; p <0,05).
Alternaria leaf spot of chilli caused by Alternaria alternate is an important disease affecting chilly production areas in India. The disease is primarily controlled through the use of fungicidal seed treatments. In this study, different fungicides viz. Captol, Captan, Ziram, Captofol, Thiram, Indofill Z 78 and Indofill Z 45 were assessed for their ability to reduce the growth of Alternaria alternata under laboratory conditions. Maximum inhibition (100%) was achieved by Captol and capton followed by captofol (89.5 %) while 0.1 % dose given. This paper reports the efficacy of fungicides that can be used under field conditions to control alternaria leaf spot in tropical regions and demonstrates the use of a method of application that could significantly improve the efficacy of disease control.
The article features the research on bronchial hyperresistivity towards direct and indirect bronchspasmal stimulus among school children with neosinophilious bronchial asthma and deletion polymorphism of genes GSTT1 and GSTM1. Significant risk of further development of children bronchial hyperresistivity is identified. Genotypes: T1+M1del; T1delM1+; T1delM1del. (ОР-6,1 95 %ДИ:2,7-13,7,ОШ-4,2, 95 % ДИ:3,3-5,3, АР-0,29)
The clinical investigations have revealed high correlation of clinical results, biochemical and instrumental examination methods with screen method data, collected from women at a late reproductive age with cardiovascular pathology.
Infants born preterm are at greater risk than infants born at term for mortality and a variety of health and developmental problems. Complications include acute respiratory, gastrointestinal, immunologic, central nervous system, hearing, and vision problems, as well as longer-term motor, cognitive, visual, hearing, behavioral, social-emotional, health, and growth problems. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. The greatest risk of mortality and morbidity is for those infants born at the earliest gestational ages. However, those infants born nearer to term represent the greatest number of infants born preterm and also experience more complications than infants born at term. Preterm birth is a complex cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, neighborhood characteristics, environmental exposures, medical conditions, infertility treatments, biological factors and genetics. Many of these factors occur in combination, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. The empirical investigation was carried out to draw correlation between preterm birth and eventuality. This paper deals with various issues related to the premature deliveries from socio-biological perspectives.
The present study was based on Diabetes, its cure & herbal products available in market. Diabetes mellitus is the most common endocrine disorder, affecting 16 million individuals in the United States and 200 million worldwide. Despite the use of advanced synthetic drugs for the treatment, use of herbal remedies is gaining higher importance because of synthetic drugs have drawbacks and limitations. The herbal drugs with antidiabetic activity are extensively formulated commercially because of easy availability, affordability and less side effects as compared to the synthetic antidiabetic drugs. Antidiabetic herbal formulations (AHF) are considered to be more effective for the management of diabetes. There are around 600 herbal drug manufacturers in India of which almost all manufacturers are developing AHF in addition to others. Till date no article is published to give detailed information of the herbal preparations on diabetes available in market. In this we illustrate about diabetes mellitus and its types, causes, sign and symptoms, complications, pathophysiology, diabetic medication, diabetic treatment, herbal diabetic cure, advantages of herbal medicines over allopathy and herbal formulations. Thus, this review article undertake the attempt for providing updated information on the type of diabetes and herbal formulations which will enhance the existing knowledge of the researchers.
The results of microbiological investigation of catarrhal gingivitis on the background of treatment with Unimag are presented in the research. Studies have revealed that treatment with Unimag of the patients with catarrhal and gingivitis rapidly normalizes quantity of microbes in the oral cavity, substituting the gram-negative pathogenic flora for the gram-positive microorganisms in the oral cavity.
The influence on date change of a cell in systematic immunity has been studied. The research implies 52 patients with different forms of traumatic disorders aged 16-69 (on average 37, 914, 28). The focus group was made up of 16 patients, who have been performed non-urgent operations not linked to musculoskeletal disorders. All focus group patients were splitted in 3 groups in accordance with their health condition. The cell system analysis of immunity was conducted by identifying of sub-populations of T-lymphocytes and antibodies CD3, CD4, CD8, and CD22.
The most vivid changes of a cell systematic immunity (II-III immunity disorders grades) were observed among patients with severe traumatic disorders. Operational intervention, even without trauma – significantly influences the cell systematic immunity, though patients with traumatic immune disorders, apart from immunoregulatory index were more significant than those of the focus group patients.
The article features literature data for treatment of patients with HIV infections as well as factors for prescription the antiretroviral drugs. The analysis of the VAART use between 1012-13 in Karaganda region was conducted. The data of in-and outpatients with HIV infections are presented. The reasons for treatment cessation and the data of ARV of HIV patients’ tuberculosis are shown.
The changes in lipid profile among patients with acute myocardial infarction (AIM) depending on polymorphism of I/D gene АСЕ, T894G gene eNOS have been researched. The research revealed, that bearing ID-genotype of ACE gene and T-allele gene eNOS is associated with total cholesterol increase (TCI) by 7,88–17,8 %, and DD-genotype – with cholesterol degrease of high density lipoproteins by 38,7 % and 43,2 % accordingly. The complex treatment of AIM patients enhanced the numbers of patients with ‘target’ TCI level and cholesterol of low density lipoproteins by 44,4 % and 52,4 % accordingly among ID-genotype bearers ACE and T-allele of eNOS gene by 51,1–60,9 %, bearers of II/TG, ID/TT, ID/TG, DD/GG and DD/TG haplotypes – by 29,5–48,6 %.