Panacea Journal of Medical Sciences

61-72

Authors: Vinayak R, Behal M

Diarrhea and pneumonia are the leading causes of illness & death in children upto 5 years of age. Zinc supplementation is effective for treatment of acute diarrhea and can prevent pneumonia. The study was carried out to compare duration of hospitalization among zinc supplemented and placebo group, in children aged 3 months to 5 years admitted with severe pneumonia: A double blind placebo controlled randomised clinical trial and to see whether the use of oral zinc therapy when compared to placebo, as an adjuvant to antibiotics, when compared to placebo reduce the duration of hospitalization by one day in children aged 3 months to 5 years with severe pneumonia. This randomized controlled trial was conducted in the Department of Pediatrics at Goldfield Hospital and Research centre, Village Chhainsa, Faridabad from 1st April 2013 to 30th April 2014. 83 Eligible Children aged 3 months to 5 years with a clinical diagnosis of severe pneumonia were taken and given Zinc supplementation for 14 days (10 mg in < 6 months age and 20 mg in 6 months or more in age) and compared against placebo groups for duration of hospitalization and other secondary variables. Results of our study showed that clinical resolution in both the groups (zinc versus placebo) was comparable in terms of median duration of hospitalization (137.23 hours versus 132.98 hours), duration of resolution of severe pneumonia (54.1 hours versus 53.83 hours), resolution of lower chest indrawing (54.1 hours versus 53.83 hours), resolution of fast breathing (69.65 hours versus 73.73 hours), time to start oral feeds (29.3 hours versus 26 hours), duration of intravenous fluid therapy (60.08 hours versus 57.43 hours) and duration of oxygen therapy (22.63 hours versus 19.80 hours). Thus there was no difference in the primary or secondary outcome variables between the zinc and placebo groups. In this randomized controlled trial, conducted to study the efficacy of zinc supplementation, as an adjunct to antibiotics, in the treatment of severe pneumonia, we conclude that short term supplementation with zinc, given during the course of illness does not shorten the duration of resolution of severe pneumonia in children between the age group of 3 months to 5 years. Zinc supplementation also does not shorten the duration of resolution of lower chest indrawing, fast breathing and inability to feed. Zinc supplementation also does not shorten the duration of intravenous fluid therapy, oxygen therapy and duration of hospitalization.

78-80

Authors: Sable M, Sable S, Kowale R, Ingole A, Somwanshi SD

The purpose of this study was to evaluate lung functions in forty athletes and forty non-athletes in age range of 13-20 years. The athletes selected for this study are given training since last three years in running event. The variables studied were tidal volume(TV), forced vital capacity (FVC), forced expiratory volume in one second(FEV1), forced expiratory volume in three seconds(FEV3), forced expiratory volume in six second(FEV6), Inspiratory capacity(IC), expiratory reserve volume(ERV), & maximum voluntary ventilation(MVV) were found significantly higher in athletes than non-athletes. The findings suggest that during adolescence, development of lung under proper nutritional and health conditions is governed by the process of growth with negligible additional effect of physical activity. However, physical exercises during growth may help in developing a reduced resistance to expiration and a greater endurance in respiratory muscles. .

85-86

Authors: Kaur S, Kawthalkar A

There is a rise in number of induced labour in modern obstetrics. Improved fetal monitoring helps in detection of compromised foetuses necessitating induction of labour. Caesarean section rate is more with induced labour as compared with spontaneous labour. Hence there is a need to evaluate current trend of induction of labour.

92-95

Authors: Litake MM, Moger J, Parasnis A

Being a rare site of metastasis, breast carcinoma metastasis to thyroid is rare. Presenting herewith a case of carcinoma breast operated one year ago in a 65 year old woman with negative for ER/PR and HER-2-neu status. She presented a year later after postoperative chemo-radiotherapy to our hospital with thyroid swellings and cervical lymphadenopathy. PET scan revealed spinal metastasis in thoracolumbar segments and suspicious thyroid malignancy. Ultrasonography of the neck was suspicious of thyroid neoplasia. Histo-pathological examination of total thyroidectomy revealed metastatic invasive ductal carcinoma of breast and immunohistochemistry was positive for GCDFP-15 and negative for thyroglobulin and TTF-1.

102-105

Authors: Gundewar T, Kale Y, Ghike S, Gundewar S

A type of morbidly adherent placenta in which chorionic villi completely invade the myometrium and may invade the serosa or adjoining organs, is known as Placenta Percreta. It is a very rare pregnancy problem and is associated with a high maternal and fetal morbidity and mortality. We present a case of placenta praevia percreta with massive intra-partum hemorrhage requiring an emergency cesarean hysterectomy.