Spontaneous retroperitoneal hemorrhage (RPH) is a rare but serious complication of polyarteritis nodosa (PAN) and must be considered in patients presenting with RPH as their first presentation. Renal infarctions, liver infarctions, and ruptured microaneurysms are all complications of PAN. We present two cases presenting with abdominal and back pain. The first patient’s abdominal computed tomography (CT) scan revealed fractured right kidney with retroperitoneal pericapsular hematoma and multiple hepatic and splenic infarcts. The digital subtraction angiography (DSA) demonstrated large areas of devascularization of the right kidney and right renal arterial wall irregularity with multifocal areas of stenosis, dilatations, and microaneurysms without active extravasation of IV contrast. She was treated conservatively and started on a pulsed dose of steroids and cyclophosphamide. The second patient’s abdominal CT angiography revealed multiple visceral aneurysms and focal areas of stenosis in branches of celiac axis and superior mesentery artery without active contrast extravasation. The DSA demonstrated multifocal areas of irregularity and narrowing in celiac and intrahepatic arteries as well as a 9 mm pseudoaneurysm in the inferior pancreaticoduodenal artery which was embolized with metallic coils. PAN has a vague clinical presentation and is clinically occult. Patients may be diagnosed while getting investigated for some other causes of abdominal pain. The emergency physician and the radiologist should be aware of the findings and should be able to correlate with pathology to prevent life-threatening complications. Angiography plays a crucial role, not only in diagnosis but also in appropriate management.
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