OBESITY IN SAUDI FEMALE POPULATION
Authors: Adil Omar Bahathiq
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An interaction of genotype and environment results in obesity which leads to a complex multifactorial chronic
disease. Obesity also involves the integration of various factors such as social, behavioral, cultural, physiological,
metabolic and genetic. Contributing to the significant increase in morbidity and mortality, a prevalence of obesity is
becoming an important public health problem.
The aim of this study is to understand obesity among Saudi female population belonging to Makkah community.
Obesity has been studied by measuring leptin concentration, and other measurements like body mass index (BMI) and
waist circumference (WC).
This study included 240 women aged between 18 and 65and the participants were divided into three groups.
The normal or control group whose BMI ranged from 18 to 29.9 comprised the first group, the obese characterized by the
BMI ≥30 formed the second group and the obese diabetic group with body mass index (BMI) ≥30 formed the third group.
The parameters collected included height, weight, and waist circumference and blood samples. Blood samples were later
Serum leptin levels in all the groups were detected using ELISA and their means found to be 8.4±1.4 in
normal56.3±18.8 in obese and 42±19.3 in a diabetic obese group. In the normal group, the leptin levels were directly
associated with BMI (r = 0.152, p = 0.178), and leptin levels showed strong positive correlation in obese and diabetic obese
groups as the follow: r = 0.350, p = 0.001 and r = 0.355, p = 0.001. Also, leptin concentrations were positively correlated
with BMI and WC in obese and diabetic obese groups, showing high leptin concentration in both the groups.
It is understood that leptin hormone influences appetite and body weight, causing obesity. However, fasting,
hypertension, practice physical activity, smoking or following special diet results in changes to serum leptin concentration.