KIDNEYS

15-24

Authors: V.Yu. Kundin, S.V. Pospelov

The article discusses the possibility of static and dynamic radionuclide imaging in the diagnostics of anomalies and evaluation of the functionality of abnormal kidney. It presents the advantages, disadvantages and possibilities of nuclear diagnostics of anomalies of quantity, size, position, relationship and structure of the kidneys. It was concluded about high diagnostic value of radionuclide studies and their use along with ultrasound screening in the observation of patients with the renal anomalies.

31-32

Authors: D.D. Ivanov

International guidelines do not recommend angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARBs) usage in the first stage of diabetic kidney disease. It shows the view, based on a small statistical sample, that olmesartan (or possibly other ACE inhibitors/ARBs) should be used to prevent the transition of the first stage of diabetic kidney disease to the second one in type 2 diabetes mellitus.

40-46

Authors: O.V. Syniachenko, Ye.D. Yehudina, T.B. Bevzenko, M.V. Yermolaieva, O.O. Diadyk, V.V. Yakovlenko

The objective of the work was to evaluate the nature of morphological changes in the endothelium of renal capillaries and arterioles in systemic lupus erythematosus, rheumatoid arthritis, hemorrhagic vasculitis and microscopic polyangiitis, the relationship with clinical and laboratory factors of the disease course and the impact of systemic vascular endothelial dysfunction. The latter takes place in 39, 35, 52 and 100 % of cases, respectively, in these groups of patients, it is involved in the pathogenetic constructions of nephropathy, is closely associated with systemic clinical and instrumental manifestations of angiopathy, and proliferation of capillary endothelium and renal arterioles, depositions in it of immunoglobulins and complement components, depending on the clinical entities of systemic autoimmune rheumatic diseases, determine the blood levels of vascular endothelial growth factor, endothelin-1, homocysteine, E- and P-selectin.

64-65

Authors: Dmytro D. Ivanov

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71-78

Authors: O.M. Korychenskyi

Пациент, 1988 года рождения, направлен для проведения допплер-УЗИ почечной артерии трансплантированной почки в связи с подозрением на ее стеноз. Из анамнеза стало известно, что 20.04.2016 г. пациенту была успешно проведена трансплантация трупной почки. Последний месяц функция почки без видимой причины стала резко снижаться, проведена эффективная терапия по купированию криза отторжения. Однако сохраняется артериальная гипертензия 2-й степени, низкая рСКФб, соответствующая ХБП 3б–4-й стадии. Возникло предположение о стенозе почечной артерии, что подтвердилось при рутинном допплер-УЗИ. С целью экспертной оценки возникшего предположения пациент подвергнут данному исследованию.