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Evaluation of In-vitro vector control activity of Physalis angulata.
Authors: Sandhya.S, Jafferi S.A.H , Vinod K.R, Ottilia Banji, David Banji, Chaitanya R.S.N.A.K.K, Chandrasekhar J, Venkataramana.K .
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The present study was undertaken to evaluate anthelmintic and larvicidal activity of crude ethanolic leaf extract of Physalis angulata belonging to family Solanaceae. Pheretima posthuma was used as the test worms. Various concentrations of ethanolic extracts were tested in the anthelmintic screening, which involved the determination of the time of paralysis (P) and time of death (D) of the worms. Piperazine citrate was included as the standard reference and distilled water as the control. In the case of larvicidal activity, the study was conducted on Culex quniquefasicatus species of mosquito larvae and the rate of larval mortality was calculated. The results indicated that the crude ethanolic extract significantly demonstrated paralysis and also caused the death of the helminthes especially at a higher concentration of 50 mg/ml, as compared to standard reference piperazine citrate. Similarly, very optimistic results were observed for Culex quniquefasicatus species of mosquito larvae and LC50 value was calculated as 51.8802 mg/l.