Çağdaş Tıp Dergisi = Journal of Contemporary Medicine

1-5

Authors: Fatih Fırat , Fikret Erdemir , Engin Kölükçü , Doğan Atılgan , Bekir Süha Parlaktaş , Nihat Uluocak

Aim: The aim of this study is to evaluate the effect of histologically diagnosed prostatic inflammation on serum prostatic specific antigen (PSA) levels and lower urinary tract symptoms. Material and Methods: Between January 2005 and January 2012 a total of 546 patients who underwent transrectal ultrasound guided prostate biopsy were evaluated retrospectively. The patients were divided into two groups are as follows; Group 1 (n=333): Histologically detected prostatic inflammation group and group 2 (n=213) only benign prostatic hyperplasia group. The serum PSA levels and lower urinary tract symptoms were compared between the groups. To evaluate the lower urinary tract symptoms International Prostate Symptom Score (IPSS) was used. Scores of 0 to 7, 8 to 19, and 20 to 35 represent mild, moderate, and severe symptoms, respectively. Results: The mean age of the patients was 64.86±7.86 years and 63.69±7.89 years in group1 and in group 2, respectively (p>0.05). The mean PSA values were detected as 10.32±8.39 and 9.63±9.69 in group1 and group 2, recpectively (p=0.016). IPSS scores were 15.52±5.76 and 13.46±6.04 in group 1, and in group 2, respectively (p<0.001). Conclusion: According to these results we can say that chronic prostatic inflammation (type 4) may be related with lower urinary tract symptoms. In addition, it is understood that histologic prostatic inflammation which was detected by prostatic biopsies effect on serum PSA levels.