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Clinical features, management and outcomes of pediatric pleural empyema: A retrospective, multicenter cross sectional study
Authors: Shahnaz Armin1 , Abdollah Karimi1 , Fatemeh Fallah1 , Roxana Mansour Ghanaei1 , Sedighe Rafiei Tabatabaei1 , Seyed Alireza Fahimzad1 , Seyedeh Mahsan Hoseini-Alfatemi1 , Maryam Rajabnejad1 , Hamid Eshaghi2 , Gholamreza Soleimani3 , Hosein Heydari
Number of views: 217
Objectives: To evaluate clinical features, treatment strategies, and
outcomes of pleural empyema for children who were treated at
referral pediatric hospitals in 8 provinces of Iran.
Methods: In this retrospective, multicenter cross sectional
study, we retrospectively retrieved patients’ data from 8 teaching
hospitals during 2010 and 2017. A questionnaire was applied and
filled, and all data were statistically and descriptively analyzed.
Results: In total, 191 children (109 males and 82 females) were
included. Their mean age was 4.95 years and ranged from 11
months to 16 years. The majority of cases (45.1%) were 1-4 years
old. Fever (70.3%), cough (65.6%), tachypnea (53.1%), chest
pain (14.6%), and abdominal pain (12%) were the most common
manifestations at admission. The mean length of admission in
hospital was 16.4 d. Consequently, 27 patients (14.1%) were
admitted into the pediatric intensive unit because of severe illness,
and 15 patients (7.9%) died. Logistic regression analysis showed
that younger age (less than 12 months) and presence of underlying
diseases (such as cardiovascular disease, immune deficiencies,
malignancies, and neuro-developmental delay) significantly
increased the mortality rate of patients with pleural empyema
(P=0.004 and P=0.001, respectively).
Conclusions: Pleural empyema children of younger age and
with underlying diseases are at higher risks of death. In addition,
guidelines for treating pleural empyema should be developed.