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A cholestatic syndrome may be a surprising cause of medical error
Authors: Mihăiță Pătrășescu, Petruț Nuță, Raluca S. Costache, Săndica Bucurică, Bogdan Macadon, Andrada Popescu, Mariana Jinga, Florentina Radu Ioniță
Number of views: 342
Autoimmune cholangitis defines a spectrum of cholestatic liver diseases that are
characterized by inflammation of bile ducts and a reasonable response to immunosuppressive
therapy. The two most common diseases associated with this term in the literature are: an overlap
syndrome of primary biliary cirrhosis and autoimmune hepatitis and a form of hyper IgG4
syndrome (currently associated with autoimmune pancreatitis). Liver biopsy is mandatory for the
diagnosis. There are, whatsoever, in clinical practice, many cases that do not meet current
diagnostic criteria but that have a good response to corticosteroid treatment.
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