Варненски медицински форум (Varna Medical Forum)

10-14

Authors: Meglena Angelova, Stoyan Pavlov, Veselina Mihaleva, Vanya Goranova, Anton Tonchev

Transcriptional factor Sox2 is a key component in a network of genes controlling the faith of diverse types of stem and progenitor cells in the developing brain. Its important role in self-renewal and maintenance of multipotency of embryonic neural progenitors is well established in a number of mammalian species. However, the data about the expression and function of Sox2 in thе human fetal brain are scarce аnd controversial. In the present investigation, we studied Sox2 expression and its rostro-caudal dynamics in human telencephalon at 20th gestational week. Using a standard immunofluorescence technique positive cells for this transcriptional factor were visualized. Their numbers and relative portion were determined and compared in specific germinal zones аt various levels and in different areas of the telencephalic cortex. When studying Sox2 expression we discovered significant differences in the numbers of positive cells in all three germinal zones (ventricular, inner subventricular and outer subventricular) in rostro-caudal direction. From rostrally to caudally the relative portion of Sox2 positive cells in the ventricular zone did not showed a significant change, in the inner subventricular zone there was a significant reduction and in the outer subventricular zone there was a slight increase. The differences described in the expression of transcriptional factor Sox2 may be of significance for a better understanding of processes related to the development, differentiation and migration of neural stem/progenitor cells in the human telencephalon during fetal neurogenesis in normal and pathological conditions.

22-28

Authors: Diana Radkova, Kalina Stoyanova, Tatyana Tsvetkova, Antonio Antonov, Stoyan Pavlov

Malaria is one of the most popular tropical parasitic diseases in the world. In our country, the disease occurs as a deposit form in bulgarian or foreign citizens, visited areas with endemic distribution. The purpose of this study is to present a clinical case of an import severe tropical malaria, complicated by renal failure and hemolytic anaemia in 45- yearold man, hospitalized in University Hospital “St. Marina” Varna. We describe the clinical features, outcome and treatment of the disease.

33-35

Authors: Todor Todorov, Ilia Todorova, Mariyana Mihajlova

The authors reveal the most common reasons for incidents in manual medicine. The main factors for failure in this type of therapy are insufficient knowledge in manual medicine and difficulties in diagnostic, resulting of veiled contraindications and individual anatomic specifics. In order to minimize the risks manual therapists need frequent courses to keep high level of competence. They also should react fast in case of complications and to switch to treatment immediately.

41-44

Authors: Antoaneta Tsvetkova

The access to medicines and other medicinal products depends on the ability of certain socioeconomic groups to influence the quality and quantity of pharmaceutical products on the market. They have a decisive role in settling issues related to the poor access of patients to medicinal products. These groups comprise representatives of pharmaceutical companies, pharmacy owners, pharmacists, medical distributors and politicians engaged in health care policies.

52-58

Authors: Maya Doychinova

The objective of the survey is to determine the extent and the nature of caries prevention on adult patients among dentists practicing in Varna. The analysis is performed based on the opinions of 120 dentists, surveyed by direct individual questionnaire, on personal contact basis, for a period of 120 days. Statistical analysis is performed with SPSS. The share of dental practitioners who have never prepared an personal caries preventive program is 77,5%. The Clinical Oral hygiene is the only approach used by 58% when caries prevention is concerned. More than half experience difficulties with the management of white enamel lesions. (88%) There is a statistical relationship between the proportion of people who have difficulties with the management of caries incipience and the expected duration of clinical time for prevention. There is strong evidence of neglecting a basic component of caries prevention in adults - the preparation of personal prevention program. Caries prevention is performed by the method of clinical oral hygiene and chemical inhibition of biofilm. Innovative approaches and methods in caries prevention are not cited. The most preferred duration of preventive clinical procedure is 45 minutes.

64-72

Authors: Mila Georgieva

Introduction: In different periods of the history to the public relations (PR) were assigned various tasks - mobilizing population in hostilities, discredit political opponents, imposing religious ideas, sell products, information dissemination. Using PR is already mandatory for any organization that wants to create a positive image in the community, to attract followers and to realize its objectives. Objective: to present the essence, methodology and experience in the PR policies and the establishment of corporate image of modern Bulgarian hospital. Material and Methods: We studied literature and borrowed the experience of the largest university hospital in northeastern Bulgaria - University Hospital „St. Marina“ - Varna. Results and discussion: highlighted are the basic concepts and methodology for PR. Tactics of PR and corporate image that modern hospital may apply for creating image in the public are presented and in particular: 1. Media Relations; 2. Own media; 3. Corporate Identity; 4. Special events; 5. Exhibitions and fairs; 6. Sponsorship; 7. Advertising; 8. Leaders of public opinion; 9. Corporate Citizenship (Public Affairs); 10. Investor Relations. Conclusions: Knowledge and application of PR to form a corporate image of the hospital is important to create the desired image by the hospital managers. A positive image of the hospital is essential to achieve a leadership position and successful performance of the hospital, both on the national and the European healthcare market.

78-83

Authors: Emiliya Baeva, Galina Petrova, Todorka Kostadinova

The article analyses the need for change; priorities, strengths and weaknesses, opportunities and challenges in the healthcare institution from the point of view of its staff. The conclusion drawn is that the employees of MHAT “Dobrich” largely accept the need for changes in the present management model of the institution. Among the main reasons for resistance to change are the lack of information and training, followed by insufficient funds and professional preparation.

88-92

Authors: Galina Petrova, Denko Zagorchev, Todorka Kostadinova

The publication aims to represent a research regarding the contentment of patients and physicians – specialists, in Diagnostics and advisory center ‘St. Ivan Rilski” – Varna, as well as the possibilities for development of the market management in the said Diagnostic and advisory center. The information is gathered through an inquiry among patients and employees of the said health institution (HI). Prevailing are satisfactory responses and opinions among both groups. The development of the market management of Diagnostic and advisory center “St. Ivan Rilski” EOOD Varna is connected with the design of a market strategy for the supply of new products with high market growth and possibilities for reinvestment of financial funds in them.