Studia Universitatis Moldaviae. Stiinte reale si ale naturii

8-13

Authors: Lidia COJOCARI, Aurelia CRIVOI

The process of adapting to a program activity is a complex reaction in the evaluation of which play a particular role regulating relations between systems and functional activity. The cardiovascular system has an enhanced reactivity among the first to include the mechanisms for maintaining biological balance of the body. Working in night hours distort physio¬logically functional stereotype, leading to temporary discrepancy between his behavior and providing vegetative body.

19-21

Authors: Eugeniu DUDNIC, Ecaterina ERHAN, Natalia DUDNIC

The people involved in the field of sport need to be informed permanently about the factors that influence the food ration, food intake, use of substances and nutritional supplements. In the experimental study conducted to investigated the effect of high doses of soybean protein on some hematological indices in the animal body.

29-36

Authors: Светлана ЖУБЫРКЭ, Светлана ГАРАЕВА, Анна ЛЕОРДА, Влада ФУРДУЙ, Галина ПОСТОЛАТИ, Галина РЕДКОЗУБОВА, Нина КОВАРСКАЯ

The article discusses the features of amino acid metabolism and nitrogen metabolism products among minors in the third trimester of pregnancy. It was found that the exchange of aromatic amino acids, particularly tryptophan, with a high probability of developing depression reflects minor pregnant, and immune status at less and less stable than in adults and pregnant women may contribute to clinical manifestation of a large number of infectious symptoms. Also there is a sharing of sulphur-containing amino acid imbalance. The coefficient is indispensable / replaceable free amino acids, indexes C, tyrosine/phenylalanine, so as homocysteine, and amino acid dicarboxylic concentration be recommended as indicators for screening pregnant women at risk for the purpose of prenatal diagnosis and implementation in practice of genetic counseling.

41-45

Authors: Ala CHERDIVARĂ, Angela RUDACOVA, Serghei RUDACOV, Andrei ŞUTOV

The final product of trypsin limited proteolysis of a subunit of storage 11S globulin from peanut seeds Ara h3 (pdb|3c3v) consists of the intact -chain and -chain fragments K and N. The fragment K disulfide bonded with the -chain corresponds to the N-terminal half of the -barrel (Ile1-Arg109), and the fragment N corresponds to the adjacent C-terminal half (Lys110-Arg213). Identification of the respective -chain cleavage points is based on the results of electrophoresis, the molecular mass of the residual protein determined using two independent methods, and on the analysis of the level of accessibility of amino acid residues in a model structure of Ara h3 hexamer molecule. The destruction of the -chain C-terminal region occurs in the course of formation of the fragments K and N. This region contains three of the four antigen determinants (IgE epitopes) identified in Ara h3. Thus, it seems likely that trypsin limited proteolysis can essentially decrease the allergenicity level of the peanut 11S globulin.

51-56

Authors: Maricica COLȚUN, Elvira GILLE, Radu NECULA, Valentin GRIGORAȘ

The paper presents the results of a vast study on the biology, chemical composition and qualitative phytochemistry of the essential oil of the species Perovskia atriplicifolia, which behaves like a perennial, herbaceous plant in the Lamiaceae family. In the Republic of Moldova, it has not been investigated as an aromatic and medicinal plant. It has a high ecological plasticity and no special requirements to climatic factors. It has febrifuge properties and is used in medicine to reduce fever. Besides, this plant is used for culinary, ornamental purposes and for air purification.

61-64

Authors: Sergiu DOBROJAN, Irina STRATULAT, Galina DOBROJAN

The present research is focused on the analysis of the blue-green alga Calothrix sp. growth process cultivated on BG-11 liquid nutrient medium. Cultivation of Calothrix sp. on BG-11 allows to obtain 2,38 ± 0,11 g/l of algal biomass during 12 days. The highest values of the daily growth of the biomass, the rate of reproduction, reproduction coefficient and the growth rate of the Calothrix sp. algal population, is found in the range from 1 to the 12th day of cultivation, but on the 15th day of cultivation the results of these indicators are significantly reduced. From the 3rd day to the 12th day of cultivation linear growth phase are carried out, and to 15th day is observed the decline growth stage.

69-73

Authors: Alexandru MÎRZA, Nina CIORCHINĂ, Ion COMANICI

Here, we established the protocol for plant regeneration of Rubus loganobaccus L.H. Bailey via in vitro micro pro-pagation. Apical meristem was used as the explants cultured on Murashige and Skoog (1962) medium (MS) supple-mented with different concentrations of plant growth regulators, 6-Benzylaminopurine (BAP). For the cultivars Logan, Chehalem, Olalie and Kotata good results were obtained for 0.5 mg/l BAP concentration, whereas for the cultivars Santiam and Lincoln Logan results were obtained for 0.4 mg/l BAP concentration. The micro-shoots produced normal roots within two weeks of culture on the 50% MS medium with no supplement of plant growth regulators. Plantlets were transferred to celled trays where they grew well.

83-88

Authors: Ana MUTU

The paper reveals a comparative synthesis of the researches carried out in the field of medicinal and aromatic plants. It is analysed the importance of correlating the phenotypic, biochemical and molecular studies for new breeding programs of various forms of medicinal and aromatic plants with economic valuable characters. On the example of the Origanum genus, it concludes about the effectiveness of genetic fingerprinting techniques to identify new subspecies and chemotypes.

96-107

Authors: Tatiana ERHAN

This paper presents a review of N(4)-arilthiosemicarbazide derivatives. The synthesis methods of N(4)-arylthio-semicarbazides and their derivatives are described. There are also represented the possible ways of modification of their biological properties. The antiproliferative activity towards HeLa, MCD-7, SW620, MiaPaCa-2, and Hep-2 cancer cells and antimicrobial activity of these substances are revealed. These biological properties make it possible to use them as the basis for the obtaining of new performant molecular inhibitors that can be used in anticancer therapy. Some ways of the development of organic synthesis for the obtaining of new derivatives of N(4)-arilthiosemicarbazides were outlined.

118-123

Authors: Ketevan KUPATADZE

Popularization of Ecological Chemistry is the aim of scientific-popular articles, which are published in the online journal for teachers. With the articles of this type Ecological Chemistry is linked with literature and history. Due to this linkage articles, this module turns into an easily comprehensible one and it becomes fun. In all articles there is also included very useful and interesting information pertaining to Ecological Chemistry. It must be underlined the titles of such articles, because they should not only show the common meaning of article, but they should also attract readers. The utmost interest is generated by the historical papers, where chemical issues are connected with history. The period of alchemy is more popular and that’s why the alchemical stories are described in the articles. The outcome of the pedagogical experiment has made it clear, that such a method of teaching of Ecological Chemistry with scientific popular articles affects positively on school students motivation and changes their attitude towards the environmental pollution.