GISAP: Medical Science, Pharmacology

5-11

Authors: Dzvenyslava Moskvyak-Lesnyak, Vasyl' Ruden'

In the context of disturbances of the menstrual cycle and perimenopause among women (n=400/624, р<0,05) with a diagnosis of breast cancer (C50) and women of the control group (n=400/1335004, р<0,001) following risk factors for occurrence/development breast cancer pathology (C50) were determined: early – onset of menarche at age 10 years (1,00±0,50%, р <0,05), 11 years (5,75±1,16%, р<0,05), 12 years (13,25±1,70%, p>0,05) and late – at age 15 years (16,25±1,84%, р<0,01), 16 years (16,50±1,86%, р <0,01), 17 years (2,25±0,74%, p>0,05), 18 years (2,25±0,74%, p>0,05); duration of menstruation till one day (2,00±0,70%, р <0,05), one day (6,25±1,21%, p<0,01), during two days (17,25±1,89%, р<0,01), more than 5 days (16,25±1,84%, р>0,05); climacteric changes at age 22-30 years (2,10±0,52%, р<0,01), 31-41 years (25,63±2,32%, р<0,01), 42-58 years (59,24±3,48%, р<0,01), 59-70 years (13,03±1,08%, р<0,01), and the duration of climacteric process for 4-5 years (23,53±1,73%, р<0,01) and more than 5 years (45,38±2,22% , р <0,01). All this is confirmed by the multivariate analysis results.

18-24

Authors: Irina Koliada, Vasyl' Ruden'

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30-32

Authors: Olena Krekoten

Some aspects of life style of employees of transport enterprises of different ownership forms have been studied using the sociological research method. Sampled selections of the main and control groups were formed. Their analysis provided verification of the suggested hypotheses. Comparative analysis was performed according to the criterion of the enterprise ownership form in two regions of the country. Dependence of the life style on social-economic and demographic factors have been determined.

36-37

Authors: Yuriy Lakhtin

The author has studied the degree of conditionality and assessment of power of cause-and-effect relation of emergence of parodontitis, dentoalveolar anomalies and teeth caries among people under the influence of salts of heavy metals in the environment. Relative and attributive risk of distribution of these illnesses is calculated.

41-44

Authors: Alexander Chiglintsev

The course of studying and statistic classification revealed that hereditary predilection and metabolic derangements in the organism determining disease initiation and development is the main causal complex of urolithiasis. All other factors cover necessary conditions to realize and release predetermined disease internal possibilities. Directed at metabolic derangements prevention and treatment activities are perspective in urolithiasis recurrence prevention.

48-49

Authors: Alexandr Guz, Sergei Jaitsev

Application of immunomodulating liniment Cycloferon in the complex chemoradiotherapy of oropharyngeal cancer allows to avoid the development of severe mucositis with erosive and ulcerative lesions and promotes non-specific resistance of the mucous of the mouth, which allows to complete therapy at the optimum time.

53-55

Authors: Danelina Vacheva

The purpose of the research is to examine, follow and report on the improvement of abilities to do daily and labor activities among patients with distal radius fracture in early and late post-immobilization period. Materials and methods: 106 patients who suffered from distal radius fracture were included in the study, they underwent a physio-rehabilitation program adjusted to each particular case which included sub-water gymnastics – local bath tub with water temperature 34-36° C, in the area of wrist joint and forearm, kinesitherapy, occupational therapy, impulse magnetic field – 15–20 min, 2 А, 1 – 100 Hz, interference currents – 5 min, 90 – 100 Hz ; 10 min 1 – 100 Hz, 10 procedures daily. Results and analysis: Comparative analysis of results shows that patients with injured non-dominant limbs have less difficulty in early post-immobilization period than patients with traumas in a dominant limb. In the end of the rehabilitation patients with injured dominant upper limbs have better test results. Conclusion: in order to get good results in rehabilitating patients with distal radius fracture and improving their self-service abilities the due beginning of the rehabilitation process and including labour therapy and everyday life activities in the form of guidelines are of utter importance. The functional labour therapy stimulates patients’ self-dependence and speeds up their return to professional and social activity.

59-60

Authors: Marina Buryak, Natalya Khokhlenkova

In this article physicochemical properties of the ointment based on thick oak bark extract and juice of Kalanchoe are studied. It was found that the total mass of water absorption of ointment was 342% - this proves good osmotic activity of the ointment. Also, it is necessary to note that the water absorption of ointment uniform and proportionate.