Journal of Medical Science and Technology

1-2

Authors: Dr S. Jothi Arunachalam

Responsibilities and humane attitude start with the dreaming about becoming a doctor. Most of the biology students want to become a doctor, which is regarded as noble profession. In this aspect I would like to share few things regarding the relationship of a medical student with their teacher (he is also being a medical professional). In the day to day life of a medical student i.e., academic career, clinical knowledge in diagnosing a disease, treating the sufferers, depends on the foundation laid by the teaching medical professional. And I feel this relationship of a medical student with his teacher should start very early i.e., from the day one of their career after entering into a medical college.

8 - 13

Authors: Dr. Umakant Valvekar1*, Dr. S.Viswanathan1

Prolactin secretion is controlled by hypothalamus which secretes prolactin inhibiting factor. Thyroid releasing factor (TRF), and thyroid stimulating hormone (TSH) have positive effect on prolactin secretion and can lead to galactorrhoea. Hyperprolactinaemia causes anovulation, amenorrhea, galactorrhoea, and reduced fecundity. With this background, the present study was planned to find out the prevalence of hyperprolactinaemia and hypothyroidism in women with infertility. Total 100 women patients of age range between 23 to 39 years were recruited for the study. Of the 100 women, 60 women were diagnosed as primary infertility and the remaining 40 were diagnosed as secondary infertility. Serum prolactin levels and thyroid stimulating hormone (TSH) levels were measured in all women. Patients were categorized based on their serum prolactin levels and TSH levels to find out the prevalence of hyperprolactinemia and hypothyroidism. The present study shows high prevalence of hyperprolactinemia and hypothyroidism in infertile women.

29 - 32

Authors: Dr S. Jothi Arunachalam

Internal jugular vein (IJV) thrombosis is an extremely rare vascular disease. It is usually secondary to intravenous drug abuse, prolonged central venous catheterization or deep head-neck infections or trauma. Associated malignancies are uncommon and not well documented in the etiology of IJV thrombosis. A 50-year-old female presented with complains of neck swelling on left side for past two weeks and with no ear or nose complaints. On examination of neck presented swelling along the anterior border of the left sternocleidomastoid muscle. An ultrasound scan of the neck neck revealed left IJV thrombosis. The patient was referred to vascular surgeon for further treatment.

38 - 45

Authors: Malladi Ramakrishna1*, Putcha Udaykumar2, Pinninti Santosh Sushma 2

Oral cancer is the sixth most common neoplasm occurring globally with an incidence rate of 6, 40,000 cases diagnosed annually. 90% of the oral cancers are squamous cell carcinomas. Although oral cancer has got multi-faceted etiology alcohol consumption and tobacco chewing are the major risk factors. These pre-disposing factors are leading to the wide range of genetic events leading to cancer progression. Despite, the significant advances in the understanding of etiopathogenesis and molecular basis of the disease as well as continuing improvement in the management strategies, OSCC prognosis remains dismal. It is widely recognized that novel, more effective approaches to diagnosis, prevention and treatment are urgently needed. The major etiological factors for oral cancer development are potentially preventable through discontinuation of hazardous habits and vaccination in case of viral infections. Primary prevention of the disease appears as a challenging goal. However possibilities for secondary prevention appear achievable i.e early detection and treatment at an early stage during the process of carcinogenesis. The ongoing of genetic and epigenetic events that govern oral carcinogenesis at the molecular level holds great promise for identifying novel diagnostic and prognostic biomarkers as well as therapeutic bio targets. Intensive research efforts have analyzed a large number of potential molecular biomarkers for the better assessment of the risk of OSCC development and progression. Further biomarkers may play a prominent role in guiding individualized oral cancer treatment, according to which selection of the most appropriate therapeutic intervention will be based on the knowledge of a given tumor susceptibility to a specific anticancer treatment.