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Socio-demographic determinants of glaucoma medications compliance: A North Indian cross sectional study
Authors: Shweta Tripathi, Shakun Gupta, Varun Arora
Number of views: 304
Introduction: To investigate the level of compliance with glaucoma medications in a clinical setting of a tertiary north Indian
hospital amongst both rural and urban patients and the factors associated with failed compliance. Thus to improve patient care
and reducing visual deterioration and loss from glaucoma.
Method: This was a Cross sectional study done at the Glaucoma Clinic, Indira Gandhi eye hospital and research centre
Lucknow, between October 2014 and March 2015. 198 patients in the clinic were administered a questionnaire by the doctor. All
patients were examined to make sure they met the inclusion and exclusion criteria and then a standard questionnaire was filled for
each patient by direct questioning and also form case records Impact of age, gender, place of residence, religion, education, social
status, knowledge about disease, systemic illness, other medical treatment, duration of treatment and number of anti-glaucoma
medication on compliance was evaluated.. Data was analyzed using SPSS version 15.0. Data has been represented as numbers
and percentages. Associations were evaluated in terms of odds ratio and tested using chi-square test.
Results: Out of 198 patients enrolled - 30.8% were females, 30.8% were in the age group of 61-70 years age group, 60.1% had
an urban background, 73.3% were aware that they had glaucoma and 66.7% were under treatment for more than 2 years.
Although rate of compliance varied among different age groups ranging from 0 to 34.4% yet this difference was not significant
The odds of compliance were higher (OR>1) among females as compared to males, urban as compared to rural, Hindus as
compared to Muslims, 12th Class/ Graduates as compared to Uneducated/Primary educated, Higher socioeconomic strata as
compared to other socioeconomic strata, those having knowledge about disease as compared to those not having knowledge
about disease, having shorter duration (<2 years) of disease and those taking single AGM as compared to those taking multiple,
however, this difference was significant statistically only for place of residence, education, social status, duration of treatment
and number of AGMs only (p<0.05).
The commonest reason cited for non-compliance was side effects (26.3%) of anti-glaucoma medications. Other causes
included cost factor (19.2%), forgetting schedule (17.7%), depletion of medication before next appointment (14.6%), inability to
understand instructions (12.2%) and loss of prescription (4%).
Conclusion: Compliance rates were quite poor and were mainly associated with demographic factors, duration and number of