International Journal of Ayurveda and Pharmaceutical Chemistry

5

Authors: Sreekutty P V, Shrinidhi R2 , Shubha P U3 and Chaithra S Hebbar

Agadatantra has an ancient and established background in Kerala. Ayurvedic toxicologists of Kerala regarded some treatise as their authentic reference books. Kodeserymargam is one such exclusive reference book which covers the entire aspect of Visha and its management. There are many Agada Yogas mentioned in the management of Lootha Visha. Nigundyadi agada is one such formulation mentioned in Kodeserymargam, which contains ten ingredients. It can be used in the form of Gutika, Kasaya and Lepa.

5

Authors: Sanjeev Kaushik, Shweta Bisht2 and Jyoti Kumari

Anaemia can be closely correlated to Panduroga in Ayurveda. Reduction in Red blood cell(RBC) and haemoglobin is main characteristic feature of this disease. Heamoglobin estimation is the one of the most important diagnostic tool for Pandu (Anemia).Transfusion dependent anaemia is form of anaemia characterised by need of continues blood transfusion .It is condition that that results from various diseases,and associated with decreased survival rates.Clinical presentation of Panduroga are explained by different Acharya-Mandagni (suppression of power of digestion), Daurblaya (weakness) Bhrama(Giddiness), Jwara(fever), Swasa (Dyspnoea),GuruGatrata (Heaviness), Shoonakshikutta (swelling peri orbital region), Sheernalooma (hair fall), Pindikoudvesthan ( Cramps in calf regions), Arohanayasha (while climbing feel pain in calf, lumbar and feet, region thigh). This is a case study of a 19‑year‑old female patient from Delhi presented with blood transfusion dependent Aneamia to Kayachikitsa outpatient department at CBPACS,Najafgarh,Delhi Ayurveda treatment regimen containing herbal‑mineral based and metallic preparations was administered for a period of approxiamately 2months, which resulted in marked rise in hemoglobin level, hematocrit, red blood count . Multidimensional approach of Ayurvedic medicine and principle can prove to be very effective in the management of this anemia.

6

Authors: Divya Hule, Nilakshi S. Pradhan

Myopia, a prevalent visual disorder, has been on the rise globally, leading to concerns about its long-term impact on ocular health.According to Ayurveda, involvement of Patala by various Doshas is responsible for development of refractive errors. Acharya Sushrut and Acharya Vagbhat have recommended various Kriyakalpa and treatments like Nasya, Dhumpana, etc. among which Tarpana is considered as foremost in management of Timira.Refractive errors are an avoidable cause of visual impairment and are in utmost need to be considered for subsiding its further progression in blurred vision by prescribing appropriate glasses or last option being refractive surgeries.This study explores the potential of Tarpana, an Ayurvedic ocular therapy, as a novel approach in myopia management. The results revealed promising findings, suggesting that Tarpana might serve as a complementary therapy in the management of myopia. These findings have significant implications for the field of ophthalmology, shedding light on potential alternative treatments for myopia and encouraging further research into holistic approaches for visual health.

7

Authors: Neha Rokhade, Shrinidhi R2 , Ranjana K3 and Chaithra Hebbar

The Visha Chikitsa has been given prime importance and explained by all Acharayas. There are various Agada formulations explained in Visha chikitsa by many Acharyas. Among them some are under clinical practice and some are unexplored due to lack of research works. One such formulation Rajanyadi Lepa explained in Yogaratnakara Vishadhikara 73rd chapter in the context of Lootha Visha Chikitsa. It comprises of 5 ingredients and administered as External application. Lepa is extensively used by Visha Vaidya as a mode of treatment even i in this present era. This paper is an attempt to make a review on the formulation Rajanyadi Lepa

7

Authors: Geetha Kumar, Anop Singh2 and Manish Choudhry

INTRODUCTION: Kurpara Sandhi Marma is one of the Vaikalyakaramarma. If injured it produces deformity or disability of the person. Many types of sports injuries like Tennis elbow, Golfer’s elbow etc. are related with elbow joint which will be leading to deformity that can be avoided by proper Ayurvedic treatment. METHODOLOGY: Marma related reference from Samhitha with commentary and modern anatomy books and sports injury related articles are referred. RESULT: Kurpara Marma mentioned in Ayurveda can be anatomically compared with elbow joint. Over excretion of joints and straining of ligaments during sports related actions leads to conditions such as Tennis elbow. This condition is characterized by pain in the region of medial and lateral epicondylar of elbow pain, and when untreated leads to permanent loss or disability of the limb. Ayurvedic treatments such as Abhyang (application of oil) and Pichu (application of cotton-soaked with medicated oil) can be adopted to avoid permanent disability. DISCUSSION: The article discusses about Acharya Sushruta description of Kurparamarma which is located in upper extremity situated in between humerus radius and ulna bone. Its measurement is 3 Angula Pramana and its prognosis after injury produces Kuni. Elbow joint is synovial joint functionally hinge type joint found between lower end of humerus and upper end of radius and ulna. The point of articulation of three bones the humerus radius and ulna. The articulation of elbow joint occurs between the Trochlea and Capitulum of humerus and trochlear notch of the ulna and head of radius. In Ayurvedic point of view Kurpara Marma Abhighataja leads to deformity of elbow, produces swinging of arm, stiffness of arm, painful movement of upper limb. Conclusion: In day-to-day life, improper use of forearm and arm, any nerve injury, muscle weakness, by various sports activity will hamper the function of elbow joint, so we have to prevent the joint from injury as well vaiklalyatha (deformities) by medicated oileation, sudation, application of cotton dipped in medicated oil (Pichu), proper massage, traction, exercise etc.

9

Authors: Vijayendra G Bhat, R Santhoshini2 and Niveditha YR Hebbar

Metabolic syndrome is a complex cluster of interconnected metabolic abnormalities that significantly increase the risk of cardiovascular diseases, diabetes, and other chronic conditions. Ayurveda is one of the traditional medical systems that has drawn attention for its holistic approach to treating illness. This paper is a case study demonstrating the effective use of Ayurveda therapies in the management of Metabolic Syndrome focusing on lifestyle modifications and herbal remedies.

11

Authors: Jyoti M Takoliya, Ankit M. Paneliya2 and Upendra U Zala

The Varti Kalpana has play its own important role since prehistoric period. Varti Kalpana is derived from Vati Kalpana explained in Ayurvedic Pharmaceutics. Varti shape i.e. like wick of lamp (elongated with tapering ends) that is why it is called Varti Kalpana, medicated preparation, intended for ready to introduce into one of the cavity of the person‟s body other than oral cavity. These are intended for local application and helps in expelling the accumulated Doshas. Ayurveda describes Netra Varti, Dhuma Varti, Guda Varti, Yoni Varti, Vrana Varti. In our classical literatures, exclusive description of Vartis were found and they describe their distinctive method of preparation, specific size as well as administration and indication in disease. Suppositories are solid dosage form prepared by moulding or pressing to be inserted into body cavities such as the rectum, vagina and the urethra. Guda Vartis are intended for insertion into the rectum (Guda). Rectal route of drug administration incorporates absorption of a drug through vessels to exhibit desired therapeutic action. Guda Varti helps with Apana Vayu Anulomana by assisting in the easy elimination of Sanchita Dosha from the body. Various method of its preparation has been explained both in the classical literature and in contemporary science.