International Journal of Ayurveda and Pharmaceutical Chemistry

5

Authors: Ashutosh Pandey, Hemangini Dubey2 and Anand Chaudhary

There has been escalating wakefulness and universal adequacy of the utilization of ayurvedic medicines in today’s medical and alternative profession. Renaissance of public awareness in traditional medicine is escalating in all the countries. This augmentation in the use of ayurvedic drugs has also given rise to a variety of abuse and adulteration of the ayurvedic drugs important to consumers and manufacturers leading to the lethal penalty. Quality evaluation of ayurvedic drugs is a significant tool in the preparation of high quality AYUSH/Herbal drugs. The present work seeks to enlighten the stakeholders in AYUSH products on necessitate to ascertain the quality consideration with the help of higher analytical tools and well defined standardization methods. In this article a study has been made to fix the parameters including Macroscopic analysis, Microscopic analysis, Quantitative analysis, Qualitative analysis, Limit Tests, Microbial Limit Tests, Pesticide Residue, Test for Aflatoxins etc and Biological evaluation (Pharmacological evaluation, Toxicological studies in order to ensure the use of only genuine ayurvedic remedies. The obtained values/ranges can be used as standards for quality control of the AYUSH/Herbal products.

5

Authors: Gunjan Sharma, Barkha2 and Priyanka Rani

Ayurvedic preventive and therapeutic concepts depend on keeping Agni strong and preservation of harmony between Jatharagni (Internal digestive fire) and Kostha (excretory system). Triphala which comprises three fruits powder in equal amounts, is the most well known Ayurvedic formulation. Haritaki (Terminalia chebula ), Vibhitaki (Terminalia bellirica) and Amalaki (Emblica officinalis) a very powerful Chakshushya Rasayana (visual function rejuvenator). Triphala Churna act across all three Doshas(body humours) i.e. effect of Haritaki- on Vata Dosha, Amalaki-takes control of Pitta Dosha and Vibhitaki- acts on Kapha Dosha. The role of Triphala Churna in treating ocular disorders given by Acharya Sushruta in Sutra Sthana. The anti-oxidative and anti-inflammatory effect of Triphala Churna exhibit diverse beneficial properties in ocular disorders. Shushkakshipaka (Dry eye syndrome), is Vatapitta dominant ocular disorder in which the Ashru (Tears) has been depleted resulting in Paka (Inflammation) of eye. Present study has been undertaken with the aim to develop the physiochemical profile of Triphala Churna. Pharmaceutical analysis of Triphala Churna preparation was done according to API & protocol of drug testing of PLIM Material and Method: Triphala Churna was assessed for Physical characterization, physicochemical study, Microbiological Analysis and heavy metals analysis. Result and Discussion: Triphala Churna is safe for use as heavy metals were below the acceptable limit and free from any pathogenic microbes. Conclusion: The Sushruta Samhita method was used to prepare Triphala Churna. This paper presents the analytical study of Triphala Churna.

6

Authors: Shweta Rawat, Sanjay Kumar Tripathi2 , Sanjay Kumar Singh3 and Sandeep Kumar Tandon

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, present in 20 to 40 percent of the general population. In the US, NAFLD is 3-5 times more prevalent in men than in women. The prevalence of NAFLD in india is 9-32%15. In this case, grade 1 fatty liver is reported. A male patient came with a complaint of aruchi, avipaka, udara shoola, anaha and incomplete evacuation to the Rishikul ayurvedic medical college, Haridwar. Haematological examinations altered in SGOT, SGPT, alkaline phosphatase, bilirubin and USG abdomen. Ayurvedic treatment was given to patient for 2 months. After two months, haemotological tests and USG results return to normal. The objective of the current case study is to assess changes in a patient's subjective and objective metrics that showed signs of NAFLD. Rohitakadi vati is a formulation mentioned in Bhaishajya ratnavali. Thus, the drug Rohitakadi vati is an effective vati to treat NAFLD.

6

Authors: Hemant Kumar, Neerja R Sharma

Computer Vision Syndrome arises now days due to long time and improper working on computer. Computer Vision Syndrome has symptoms like Headache, Dryness of Eyes, Eye Fatigue, Redness, Burning in the Eyes and Itching in Eyes. In Ayurveda Shushkakshipaka have these symptoms same as Computer Vision Syndrome. The main aim of our study is to manage these diseases with Ayurveda which will cure the disease from its root cause without any side effects. So, the effort has been made using Trataka a Yoga kriya and Goghrit Aschotana in the management of Computer Vision Syndrome. A male patient of Age 42 years with history of Computer Vision Syndrome from last one year. The Patient have all classical symptoms like Headache, Dryness of Eyes, Eye Fatigue, Redness, Burning in the Eyes and Itching in Eyes comes at O.P.D of Govt. Ayurvedic Hospital Model Gram Ludhiana. The testing of dryness of both eyes was done with Schirmers Test and found R.E has 8mm wetting in 5 min and L.E has 9 mm wetting in 5 min. Patient was using Tear plus eye drops and also taking antihistamine drugs daily from last nine months. So, this case of Computer Vision Syndrome is treated with Trataka a Yogic Kriya daily in the early morning followed by Aschotana of Goghrita for four weeks. It was observed patient got good relief in the all symptoms of Computer Vision Syndrome.

6

Authors: Gunjan Sharma, Kanchan Pant2 and Priyanka Rani

Eyes are contemplated as key sense, as the world is visible to us because we are blessed with eyesight.Importance of vision has been described in our classics by stating Drishti Pradhantamavata.Timira is one of the Drishtigata Rogas specified by Ayurveda Acharyas which presents with blurred vision initially and if left untreated may lead to complete loss of vision.Shreshthadi Kwath Vati is a modified form of traditional Ayurvedic herbal formulation. Shreshthadi Kwath mentioned in Yoga Chintamani.The formulation is believed to cure ocular disease such as Naktyandha,Timra,Kacha and Patala Rogas.To overcome the problems of palatability,feasibility,shelf life with Kwath form of drug,effort is made to modify it into Vati form i.e. Shreshthadi Kwath Vati.This paper is made to standardize the formulation through pharmacognostical and pharmaceuticals measures.Pharmaceuticals analysis of Vati preparation was done according to API and protocol of drug testing of PLIM.The formulation is safe for use,as heavy metals were below acceptable limit and free from any pathogenic microbes.

7

Authors: Anwar Khan, Prasad Gaikwad2 , Vishakha Morankar

Rheumatoid arthritis is a chronic inflammatory disease widely prevalent throughout the world. It is one of the most crippling diseases in which joint pain and swelling are cardinal features. The disease strikes women three times more often than men. In Ayurveda, it is co-related with the Aamvata in which vitiated vata and Ama plays a major role. Symptoms like joint stiffness and swelling affect the daily life of a patient and make him feel handicapped. A 51-year-old female patient presented with severe joint pain, swelling & restricted movements; was treated with Arogyaved’s herbal formulations & bone joint detoxification therapies. After 3 months of treatment pain subsided and satisfactory improvement was found in swelling & restricted movements. Detoxification in the form of basti regimen & external therapies is surely a result-oriented therapy in the management of rheumatoid arthritis. We are glad to share the excellent results in treating the RA case.

7

Authors: Bhavin M.Chavda, Bharat D. Kalsariya2 and Darshan K. Parmar

Trinakantamani (Kaharuba, Kaherva, Kerbo) is incorporated in Ayurveda from Unani system of medicine in 19th century. Trinakantamani Pishti is well-known formulation of Ayurveda used for Raktarsha, Raktapitta and Raktapradara. It is described in Bheshaja Samhita, Bhasma-Pishti Prakarana. In present study raw drugs were authenticated with Ayurvedic Pharmacopeia of India parameters. Bhavana Dravya used for Trinakantamani Pishti were S0hweta Aparajita Mula Kwatha, Jambiri Nimbu Swarasa, Ashwattha Tvak Swarasa and Shatavari Mula Swarasa. Color of Trinakantamani powder changed from dark yellow to light brown. Average liquid media used for Bhavana were 140, 113.33, 150 and 118 ml respectively. There is no any major changes found in all the batches of Trinakantmani Pishti. Standard manufacturing process was developed by preparing three different batches. Trinakantamani Pishti prepared by this method did not found any substantial difference in pharmaceutical procedure. Physico-chemical parameters for each batch did not show any major changes in all the parameters except in sulphated ash.

9

Authors: Shubham Bansal, Roushani Kalia

INTRODUCTION- The present case was diagnosed with kapha pradhana ekkushtha. The line of treatment followed was Samshodhana followed by Shamana chikitsa. Patient’s main concerns were the symptoms viz. severe itching, excessive scale formation, and skin lesions all over the body which had foul odour, stress that resulted in erectile dysfunction. Kapha pradhana ekkushtha was the primary diagnosis made. Virechana therapy followed by oral medication for roga shamana was the line of treatment followed. CONCLUSION: The use of Aragwadhamahatikta ghrita during snehapana and brihatdantphala tailam for local application provided significant results

10

Authors: Anita, Gourishankar Rajpurohi

Poisoning-related illness and fatalities are a global concern. The term "poisoning" can refer to Dooshivisha, Garavisha, and other radiations in addition to animal and vegetable poisons. Ayurveda has outlined various poisoning treatment options. Panchkarma therapy has great importance because it can remove toxins from deeper tissue level. The use of Panchkarma procedures depends on the poison's absorption and entry points. This article's conclusion describes how Visha Chikitsa, a detoxification therapy, can benefit from Panchkarma practices

10

Authors: Divya Gupta, Neeraj Agrawal2 , Lowkesh Chandravanshi3 , Seema and Hemant Chouhan

Swarnaprashan is a classical gold preparation,especially advised for paediatric age groups.Many years back in Ayurveda literature, this unique combination of drug was defined by Acharya Kashyap, one of the best literatures of Ayurveda regarding paediatric care. Swarnaprashan is a mineral drugs formulation, processed with Swarnabhasma,honey and ghrita. Swarnabhasma (nano particle of gold) is main content of this formulation so its nomenclature by Swarnaprashan.In case of children health care and treatment, choice of medicine becomes very fragile topic, as medicine for children should be easy palatable and multi-tasking. swarnaprashan can also combine with herbal drugs like bramhi, vacha, guduchi, etc to address some desirable quality.Acharya Kashyap explained evidently that administration of swanaprashan in children shows the remarkable benefits like improving the intellect power, enhance the digestive power and metabolism, increase physical strength, rasayan, boost immunity, complexion,fertility, and lifespan

10

Authors: Lalita D, Gaurav K2 and Rajesh S

The main objective of Ayurveda is to sustain the health of a healthy individual and to cure or treat a diseased or ill person. In Ayurveda, Ahar, Vihar, Dincharya, Ritucharya, Ratricharya, etc., are mentioned in detail. Several Ayurvedic herbs are briefly detailed to accomplish the aims or purposes of Ayurveda. Based on their origin, Ayurvedic medicines are mainly described as Medicines prepared from plants and designed from metal and minerals. Medicines prepared from plants are made using plant parts, i.e., Root, Stem, Flower, Fruit, Bark, Seed, Leaf, etc. In Ayurveda, five types of Panchamoola are mentioned in Samhita. When the root of five plants is taken together to prepare a formulation in Ayurveda, it is called panchamoola. Kantaka Panchamoola is one such panchamoola to be described in this article, Identification, Morphology, and medicinal properties of Contents of Kantaka Panchamoola.

13

Authors: Aakanksha Sharma, Vijay Bhushan Sharma2 and Pramod Kumar Mishra

Dyslipidaemia is the most common disorder which is associated with cardio vascular diseases, CHD, atherosclerosis etc. WHO claims that about 2.6 million deaths are caused due to raised cholesterol level. Dyslipidaemia can be defined as disturbed lipid level in blood either more or in less amount. According to Ayurveda it cannot be correlated with a single disease or disorder but the condition associated with Rasadhatugata Ama, Medsavritta Vata, Medo-dhatwagnimandya, Abaddha Medo Vriddhi, Medo-roga or Medo-Dushti can be correlated accordingly. In this situation treatment which lowers the Kapha Dosha, digests the Ama, and possess the Deepana, Pachana properties will help in lowering the lipids in blood.

18

Authors: Pooja R Singh, Santosh G Girbide2 and Savita R Gudade

In present era, the complications related to lifestyle disorders like Obesity is the commonest thing to encounter in practice. Hence, even in Ayurvedic clinical practice there has been a surge in Sthool patients and the complications related to the same has increased evidently in recent times. However, to treat any disease there should be a thorough understanding of etiopathogenesis of the same, this can be well understood through Nidanpanchak of any ailment. The conceptual study about Sthaulya has been done earlier and also many treatment protocols have been established based on the above said. As the Sthool patients not only deal with the symptoms of it but also the impediments of it, therefore the complications and impediments have to be understood thoroughly. The Ashtadosha of Atisthula mentioned by Charaka explains the impediments of Sthaulya. In this study for Ayurvedic approach the parameters are explained through the ayurvedic concepts and assessed with the help of some modern science tools. Also, there are many associations developed between Obesity and dyslipidemia. Hence this study targets on assessment of Ashtadosha in Atisthula Purusha and correlation with the dyslipidemia in such patients.