International Journal of Ayurveda and Pharmaceutical Chemistry

5

Authors: Navya K, Febin Joy

Introduction: Sushruta Samhita includes Upamana as a Pramana. Consequently usage of analogies in this revered text is extensive. Exploring the analogies reveals various aspects related to the base and the target domain involved in an analogy. Methodology: The analogy in the quote was critically studied by referring the views of commentators and thereafter collecting information related to cellular energy through internet source and contemporary books. Results: A critical analysis of one of the quote in Sushruta Samhita reveals the role of Tridosha in the production, maintenance and distribution of energy in a cell. Macronutrients play the visarjana role of kapha, enzymatic break down of macronutrients and cellular metabolism carry out the Adana karma of Pitta and rotatory movement of ATP Synthase performs the Vikshepa karma of Vata. Discussion: Abstract information conveyed by the usage of analogies when explored throws insight on the subtle aspects of the concerned topic as in the example considered here.

5

Authors: Chaitra L V

Atisara is a condition where watery stool are passed in excess several times a day through anus. Ayurvedic literature records it as both a symptom and an independent disease. Atisara can be correlated with diarrhea. Bhavaprakasha Nighantu is one among the laghutrayees, has described about 426 dravyas. Among 426 dravyas, 34 herbs are described as Atisarahara dravyas, Beside this saraloha from loha varga, Vileshaya from mamsa varga, Ajadugdha from dugdhda varga, takra from takra varga, gomutra from mutra varga, madhu from madhu varga, madhu khand from ikshu varga were also indicated in Atisara. In Ayurveda classic various drugs are described for the treatment of Atisara, so here attempt was made to enlist and analyse the drugs indicated in Atistara from Bhavaprakasha Nighantu.

7

Authors: Roshni Koted, Vijaypal Tyagi2 , Manisha Goyal3 , Govind Sahay Shukla4 and Rajaram Agarwal

The present study is carried out to evaluate the haematological effect of Draksha Avaleha in iron deficiency anaemia (Pandu) as claimed in the texts and to assess the rodents were selected for the study because of various reasons viz. ready availability, economic feasibility and wide applicability for such studies. Among the various models, Phenylhydrazine induced iron deficiency anaemia (Pandu) model has been applied in the study. The drug dose was calculated following the normal procedures and the effect was significant found in mices.

7

Authors: Rina Dodiya, Jigisha Prajapati2 , Pratixakumari Chaudhari3 , Rajesh Kumar Sharma4 and Harshit Shah

Ayurveda has immense potential to solve many challenging and unsolved problems of the medical world among them Arsha is one of the disease The prevalence rate of haemorrhoids is the highest among all anorectal illnesses, a fact that has been known for thousands of years. Arsha (Haemorrhoids) is a clinical term for a disorder in which the hemorrhoidal venous plexus is engorged and the anal cushion is abnormally displaced and enlarged. This condition is marked by prolapsed pile mass, rectus bleeding, and some anus discharge, among other symptoms. There are many different treatment methods available, ranging from parasurgical to surgical care. Despite significant advancements in the field of surgery, treatment results are still insufficient. In these circumstances Ayurveda is preferred. They are adamant that Ayurveda offers superior treatments for haemorrhoids. Therefore, it appears necessary to review the specifics of the Ayurvedic perspective on haemorrhoids.

8

Authors: Pallavi Yeshwantrao Patil

As per Ayurveda Ahara, Nidra and Brahmacharya are Trayopastambha. When they are judiciously used, they give support to the body by giving strength, colour and growth for whole life span. Among them “Aahar” is very much essential for sustainment of life of all living beings, it is stated to be responsible for both Aarogya and Vyadhi. Aacharya Charak described food substances in to twelve groups, one of them is Goras Varga (milk and its products) in which Takra included, while explaining qualities of Takra (buttermilk) said that it is used in Shoph (swelling), Udara (ascites), Arsha (piles), Grahani (colitis), Mutragrah (dysuria), Aruchi (loss of taste), Snehvyapad, Pandu (Anaemia) and Garvish (Poison). Takra which is one of Aahardravya explained in various Vyadhi Chikitsa, so the study is planned to review about Takra in detail from Charak Samhita which is easily available & can be used in curing various diseases.

10

Authors: Singh Divya, Vijayendra Bhat G

Objectives of the study- To evaluate the efficacy of Mahakalyanaka Ghrita in the management of Vataja Unmada/Schizophrenia and to study the etiopathogenesis of the disease. Methods: Design of the StudyOpen labelled clinical study with pre and post-test design. Patient Source-Sri Dharmasthala Manjunatheshwara Ayurveda Hospital Kuthpady, Udupi. Study selection- Twenty patients diagnosed with Vataja Unmada/Schizophrenia were selected irrespective of their caste, creed and gender. InterventionMahakalyanaka ghrita was administered in 24gm dose with warm water once in the morning at 8 am on empty stomach for 28 days. Follow up- Patients were treated with study medicine for 28 days and follow up period was 28 days. Total duration of study- 56 days.Statistical analysis: The statistical analysis was done using paired t test. Results: Improvement of 7.91% in Vataja unmada rating scale, 16.33% in manobhava rating scale and 9.68% in positive and negative syndrome scale was seen. Conclusion-Mahakalyanaka Ghrita is safe and effective in reducing the symptoms of Vataja unmada/schizophrenia.

13

Authors: Deepthi, Shrikanth P H2 and Likhita D N

BACKGROUND Prameha is mentioned under Ashta Maha Gada in Ayurveda classics because of the properties like Asadhyatva and Maranatmakatva. It not only harms the physiology of the body but also ends up in the formation of Upadravas like Prameha Pidaka. In the present era Prameha is correlated to DM because of the similarities in the signs and symptoms of both the diseases. Due to the multisystem involvement, varied presentation, complications and various adverse effects and limitations of currently available medications, the treatment which acts very fast without causing much discomfort to the patient is the need of the hour. In order to have comprehensive treatment mode, Daivavyapashraya Chikitsa in Prameha has to be focussed. Hence this study focusses on new aspect of Chikitsa in Prameha through Daivavyapashraya. OBJECTIVES: To evaluate the necessity of Daivavyapashraya Chikitsa in the management of disease Prameha. METHODOLOGY: Review of the classical literature including Charaka Samhita with commentary of Chakrapani, Sushruta Samhita with commentary of Dalhana, Ashtanga Hrudaya with Hemadri commentary and Ashtanga Sangraha with Shashilekha commentary and articles, internet sources and Sanskrit dictionaries bearing the description of Daivavyapashraya Chikitsa. DISCUSSION: Daivavyapashraya Chikitsa is considered as Ashukari and cures the disease without much difficulties. Prameha is one such disease which is included under Ashta Mahagada because of its incurable nature. Though there is no direct reference of implementation of Daivavyapashraya Chikitsa in Prameha in Ayurveda Classics, the present paper will do the literary analysis of the mode of action of Mantra Chikitsa on Prameha. CONCLUSION: Prameha is either Sahaja Vyadhi which may be because of Poorvajanmakrita karma or Apathya Nimittaja Vyadhi or Manasika Vyadhi, hence there is a need for Daivavyapashraya Chikitsa in the form of Mantra is definitely effective.