International Journal of Ayurveda and Pharmaceutical Chemistry

4

Authors: Jugal Kishore, Sreekala Vijayan

Agadatantra is one among the eight branches of Ayurveda. It deals with the treatment of various poisons, including bites of venomous animals. All the major texts of Ayurveda gives importance for the subject and considers it as an emergency treatment. Apart from the major texts of Ayurveda, we can also find texts written in regional languages like Malayalam, in the state of Kerala, exclusively for Vishavaidya (treatment of poisons). The article throws light on Nilitanduliyadi Leha, a formulation told in Vishavaidya Jyotsnika, a Malayalam text on Agadatantra. The formulation is told in the context of formulations that can be used in all types of poisons. It is an unexplored formulation and studies could make it useful for its future uses.

6

Authors: Ravindra Singh Baghel, Rita Marwaha2 , Pankaj Gupta3 and Nisha Bhalerao

Marmas are one of the significant parts of human body as per Ayurveda which play important role in clinical practices. Marmas are the seat of vital forces which holds the Prana in it. Marmas are the vital points of the human body and any damage to these points leads to disability or even death also. The ancient scriptures have strictly prohibited causing any injury to the Marma Sthana. Marma play a crucial role for the surgeons particularly during the course of surgical procedure over the Marma Sthana of the body. Sushrut Samhita described 107 Marma points on human body. Anatomically Marma are the junction of Mamsa, Sira, Snayu, Asthi and Sandhi. A detailed description on Marma is available in Sushrut Smahita and other literatures. Stimulating or manipulating Marma points in various diseases is known as Maram Chikitsa. Marma Chikitsa is one of them which play important role towards the natural healing. There are various methods to stimulate the Marma point like vibration, applying pressure, pinching or application of cold and hot pastes, oil, ointments or others depending upon the nature of Marma. The article deals with the understanding the concept of Marma Chikitsa and its application in the field of Ayurveda.

6

Authors: Santosh Girbide, Gitanjali Wankhade2*, Milind Kamble3 , Sandeep Kale4 , Savita Gudade5

A person is considered to be healthy when Dosha, Dhatu, Mala, and Agni of his body are in Sama Awastha (Balanced state) and Indriya, Atma and Mann all are functioning properly. Among these factors Agni is the important one. Agni in Ayurveda can be correlated with the digestive fire of the body. According to Ayurveda Agni is described as an important factor for Paka i.e., digestive and metabolic processes of the body. Once the food is ingested in body it goes through different processes like digestion, absorption and assimilation which is necessary for maintenance of life. In Ayurveda, Agni is classified into 13 types based on its site of action and various functions it performs i.e. 1 Jatharagni, 5 Bhutagni and 7 Dhatvagni. The four types of food after ingestion goes through the further digestive processes and gets transformed into Sarabhaga and Kittabhaga and this process of digestion is carried out by Jatharagni. Saman Vayu helps in increasing the digestive power of Jatharagni. This function of Saman Vayu is termed as Agnipradeepan in Ayurveda. Ayurveda states that, vitiation of Agni produces all diseases. That’s why Agni should be focused primarily in the treatment of each and every disease. This article focuses on detailed analysis of Agni vitiation in pathogenesis of various diseases in Ayurveda.

7

Authors: Reetesh Ramnani, Amit Kumar Sharma2 , Amit Mishra3 , Subhash Yadav4 and K. Shankar Rao5

Malhara Kalpana (topical medicaments) is classified under Bahya Kalpana (external application). Malhara is anointment preparation meant for external application to the skin or to mucosal membrane. Rasapushpadi Malhara is one such preparation mentioned in Rasa tarangini containing ingredients like parada, saindhava, kasisa and siktha taila having indications like Phiranga, Vicharchika ,Vrana.After preparation of Rasapushpa Siktha Taila was added as a base for Rasapushpadi Malahara. Therefore, in this study, an attempt was made to modify Rasapushpadi Malhara into cream and lotion form.For Rasapushpadi Malahara sikta tail was used as base with 5% Active part Rasa pushpa to get cream coloured Malhar as per classics.During the formulationof Rasapushadi creamfocus was on the following characteristic such as softening,thickening, richer texture and proper emulsification.During the preparation ofRasapushapdilotion focus was on low viscosity, smoothness and easy spreadability. Separation of different media, cracking of material and high viscosity were also avoided. Quality control for ability and safety of pharmaceutical products is of predominant importance. So quality control test must be carried out for such products.

7

Authors: Mishra Meenu, Shivhare Shwetal2 , SharmaVivek3 and Choudhary Deepak

Background: Ulcerative colitis is an idiopathic form of acute and chronic ulcero-inflammatory colitis affecting chiefly the mucosa and submucosa of the rectum and descending colon, though sometimes it may involve the entire length of the large bowel. The Prevalence rate of ulcerative colitis is 44.3/100,000 in the Indian population. In Ayurveda ulcerative colitis has a high resemblance with RaktajaPravahika. Aim & objectives: To study the effect of PicchaBasti and SwarnaParpati in the management of Ulcerative Colitis and to find out an effective Ayuvedic management for Ulcerative Colitis. Materials and Methods: A 45 years old male patient, diagnosed case of ulcerative colitis with complaints of recurrent abdominal cramps, loss of weight, loose motions with blood stained and loss of appetite since one year, was visited at the Kayachikitsa OPD of Pt. Khushilal Sharma Govt. Ayurvedic Hospital Bhopal. The patient was treated with PicchaBasti and SwarnaParpati. The duration of study was 30 days and follow up, every 15 days for 2 months. Assessment was done on the basis of symptomatic relief and colonoscopy report after treatment. Observation: PicchaBasti and SwarnaParpati yielded symptomatic relief and normal finding in colonoscopy after treatment. Conclusion: On the basis of result obtained, it can be concluded that PicchaBasti and SwarnaParpati can be used as an effective treatment in the management of Ulcerative Colitis.

8

Authors: Sandeep Kale, Jai Kini

Ayurved medical science has been treating patients since ancient time in India. It has unique principals and unique diagnosis based upon Tridosha. In current era there are many diagnostic methods available. Blood sample is mostly used for the diagnosis. But today’s parameters are different like Haemoglobin, Red Blood cell count, Platelets, etc. In Ayurveda, blood’s Varna Pariksha i.e. color examination method was used for diagnosis of many diseases. Hence with the help of computer and RGB color method we have developed red color shade strip according to Tridosha prominence. In this study participants are divided into two groups i.e. healthy and unhealthy. Blood samples of these patients were compared with red color strip. This study is about Varna Pariksha and its importance in diagnosis of Tridosha. So this study will be able to quantify this test by using red color shade strip. It is useful for primary prognostic diagnosis of Vata Dosha by Varna Pariksha. This study indicates black shade of red color in terms of RGB wavelength. Red (176-30), Green (38-25) & Blue (28-22). The code of black shade of red color is found in between #AF251B and #1F1A17. Healthy individual’s blood color shade is in at 50% and unhealthy individual’s blood color shade is at 60% as per red color shade strip.

8

Authors: Roopa Dodamani

Anartava is absence of artava, that is may be antar-artava(ovum) or bahir-artava(menstrual blood). The process of releasing ovum is known as ovulation, after ovulation if it is not fertilized then it flows out with cyclic menstrual blood. In Anartava this normal process of ovulation and bleeding hampers and we call it as anovulation, but it is not mandatory that both the processes must hamper together. This anovulation condition is one of the diagnostic criteria of PCOS and is one of the burning problem concerning the women health. In India, nearly 1 million women diagnosed with PCOS yearly5 . In Bhaishajya Ratnavali, Tila kwatha is explained to induce menstruation in rakta gulma rogi1 , under the context of Gulma Chikitsa. In present study Tila kwatha is selected to restart the menstruation in PCOS patients. Percentage of improvement in Group B on amenorrhea is 81%, acne vulgaris is 65% and USG is 77% and significant comparatively. Thus it can be concluded that Tila kwatha as Upashaya in the management of Anartava will enhance the quality of treatment.

9

Authors: Swabi, Garg G P 2 , Deepshikha3 and Joshi Neha

Cerebral palsy is a group of non-progressive, noncontagious, neuromuscular disorders that results from damage to the growing brain during prenatal, perinatal or postnatal period. CP is the leading cause of childhood disability affecting muscles movement and coordination, cognitive functions and development in child. Approximately 1- 2 per 1000 live births is a reasonable estimate of the incidence. Ayurveda is a holistic system of medicine, which aims to preserve health and wellness by maintain the balance between body, spirit and mind of a person and prevent the occurrence of diseases. In Ayurveda, as per disease classification and their respective clinical features, cerebral palsy is Vata Vyadhi or Vatavikara, particularly affecting Shiromarma or Shiromarma Abhighata which may manifest as Pangu (diplegia), Pakshaghata (hemiplegia), Ekangaroga (monoplegia) etc. This article explores the new horizons in management of cerebral palsy through Ayurveda as it offers various Panchkarma procedures like Udwartana, Swedana, Shashtishali pinda sweda, Nasya, Vasti etc. and various Medhya (nootropic) drugs. Ayurveda drugs and therapies not only benefit in the clinical complaints of child, but also provides nourishment, improves over all general condition and quality of life of child affected with cerebral palsy. Thus Ayurveda offers a holistic care for cerebral palsy and needs to be widely used in management of the disease

10

Authors: Nisha Garg, Srikant Kumar Panda

Sleep is a non-negotiable biological necessity. It is one of our foremost life support system of body. But unfortunately, quality of sleep is being deteriorating day by day in our society due to increasing stress. Currently fear psychosis of death caused by Covid19 Pandemic in our country even in the whole world is the most important one. Deterioration of sleep quality is also impacting overall status of human health even affecting the emotional status of the individual. The anxiety and tensions that occurs due to Covid 19 pandemic deaths and the spreading of infection is more grievous. So to tackle this problem one must have to acquire psychological immunity by boosting Sattva qualities like proper diet, good quality sleep, achara rasayana, meditation and pranayama etc. There is a strong regulatory impact of sleep and circadian system on immune functions. The inimical effects of prolonged sleep loss on immune functions shows the necessity of good quality proper sleep for maintaining our general health and homeostasis. The immune system has ability to protect us from viruses and diseases by producing antibodies to kill these pathogens. This review represents a brief overview of advantages of good quality sleep and how it contributes to the physical & psychological immune system to protect the human body from stress due to COVID-19. As there is no absolutely successful medicament against COVID-19 till date, the immune system is the best defence to combat stress as it supports the body’s natural ability to defend against pathogenic organism (e.g., viruses, bacteria, fungi, protozoan, and worms) and also defend the negative feelings for which good quality sleep is indispensable.

12

Authors: Mamta P Adhao, Premwant Gunwantrao Dongarwar

Cannabis sativa, also known as Cannabis indica or Indian hemp, is an annual herb of the family Cannabinaceae. It has been used by humans throughout recorded history for its food, fiber and medicine. It is a native to Central Asia, and long cultivated in Asia, Europe and China. Plants yielding the drug seem to have been discovered in India, cultivated for medicinal purposes as early as 900 BC. Hindu devotees offered Cannabis to Shiva during religious ceremonies, and the herb continues to have a religious association in India. The medicinal use of Cannabis has very long history. However, the sociopolitical pressure led to decline the medicinal use of Cannabis. This fast-growing plant has recently seen a resurgence of interest because of its wide applications. It is observed that, there are 210 formulations which contain Bhanga, out of which 102 contain Bhanga as one of the major ingredient, whereas in 91 formulations, it’s a minor ingredient.