International Journal of Ayurveda and Pharmaceutical Chemistry

4

Authors: Veena J. Kulkarni

The factors like, daily hangouts, travelling on bad conditioned path; uncomfortable, persistent sitting postures, over speeding, strenuous and stressful jobs put pressure and strain on the spine, here especially on the neck; on the affected neck symptoms like pain, stiffness, and numbness disturbs routine of the subject. As explained in Ayurvedic texts; cervical spondylitis comes under the Urdhvakayagat and Asthi–Majjagat Vyadhi.

6

Authors: Rahul1 *, Divyadeepak Sharma2 , Abhinav Rathore3 and Nitika Sharma

With the evolution of gadgets and information being available at the tip of fingers hereby thanking to smart mobile phones, computer and laptops a lot more has changed. They have become the part of our daily life because of which there’s a lot more pressure on eyes yielding to ocular distress resulting in dryness, eye strain, irritation, blurred vision, etc. which in whole are termed as Computer Vision Syndrome (C.V.S). Eyes are considered to be of prime importance to human as they are the source of knowledge intake and they add colour and beauty to our boring lives. Its hard to imagine life without being able to see properly. So hereby in order to maintain the efficacy and efficiency of eyes throughout the phase of gathering knowledge or being available on digital platform to attain or share information personal or professional we have thought of aschyotana of amalaki siddha jala as a precautionary measure followed by a drop ghruta instillation. Amalaki and ghruta are rasayana as known to majority

7

Authors: Chaitra L V1 * and Jayalaxmi2

Hinguleshwara rasa is a known herbomineral khalveya formulation indicated in vataja jwara. Different classical references of Hinguleshwara rasa are found with different composition. Here an attempt is made to compile about Hinguleshwara rasa according to different classics in regarding to its ingredient, method of preparation, dose, anupana, indication. References of Hinguleshwara rasa was collected from various available classical texts. Dissertation and article were also reviewed. In all the classical texts, Hinguleshwara rasa consist of three ingredients, in which hingula is a common ingredients in all the classical references. Hinguleshwara rasa of Rasa Tarangini references was commonly chosen for research and dissertation works because of less, safe, effective ingredients, indicated in vataja jwara and amavata.

7

Authors: Usha Singh1 *, Shailza Bhatnagar2 , Suman Meghwal3 , Pradeep Saroj4 , and Rina Sharma

Ayurveda being a holistic science is a treasure of measures of life, health and diseases. It is a science which deals with the knowledge of long and healthy life. In present era, everyone wants to live long and healthy life but due to their, busy life, and irregular diet and life style they suffer from many diseases. They do not attain maximum limit of their age. Ayurveda provides various rasayana therapies for healthy and long life. Rasayana therapies comprises of many compound formulations and single dravyas. Onion (sanskrita name–palandu) is a rasayana dravya mentioned by Acharya Vagbhatta, belongs to family “Liliaceae” and has latin name “Allium Cepa”. It balances vata dosha, aggravates kapha dosha and does not affect pitta dosha. Its (palandu) properties are madhura and katu rasa, guru and tikhsna guna, mild ushna virya and madhura vipaka. It’s (palandu) properties are almost similar to garlic. It acts as an anti inflammatory and reduces pain. It increases digestive power, improves body strength and immunity, boosts quality and quantity of sperm and volume of semen. It nourishes seven dhatus and enhances intelligence and memory power. It is a very common adjuvant used in preparation of food articles in India. Its regular use provides immunity to the body and if used as a medicine, cures many diseases too. Research studies also prove it to be a source of essential nutrients and antioxidants.

8

Authors: Monika Sode1 *, Pooja Sharma2 , Rahul Sherkhan3 , V.D. Mahanta4 and S K Gupta

Background- Lumbar Spondylosis is a degenerative condition which affects the lower spine. The Spine is compromised by a narrowing of the space between the vertebrae associated with growth of bone spurs (osteophytes). It is characterized by progressive loss of function and painful lumbar joint movements. Low back pain affects approximately 60–85% of adults during some point in their lives and it is responsible for about 10% of all the back pain condition. Objective-The present case report was conducted to evaluate the efficacy of Agnikarma and DIP diet in lumbar spondylosis pain by balancing local Vata and Kapha Dosha without any untoward effects within time constrain (30 days). Case presentation- A 51-yearold female, patient visited Shalya OPD with complaints of severe pain, stiffness and difficulty in forward and backward bending movement in lumbar spine for 2 years. She was diagnosed as a case of lumbar spondylosis. The patient was treated with Agnikarma and DIP diet. ResultThe patient showed significant (p<0.001) improvement in lower back pain and thyroid stimulating hormone from 4.88 uIUmL to 1.94 uIUmL within time constrain (3 month). A significant response in various symptoms such as Pain, stiffness, forward and backward movement of lumbar spine was found. Conclusion-This case report highlights the potential of Ayurvedic management in lumbar spondylosis and provides the better pathway for this disease.

8

Authors: Chaitra.B1 *and Niranjan Rao

Ayurveda is the oldest existing medical science whose principles of treatment still prove effective even in today’s changing era. The lifestyle now-a-days has become very hectic and has become a major reason for the growth of prevalence of autoimmune disorder. In this paper, a single case study has been discussed as to how there were changes in the samprapthi and how ayurvedic principles held true in the samprapthi vighatana. This patient was diagnosed with psoriatic arthritis and was subjected to virechana karma. The efficacy of the treatment before and after has been discussed in the paper and an attempt has been made to identify, a possible correlation between psoriatic arthritis and vatarakta for proper management in the future times.

8

Authors: Sarmah Jyoti Manab1 *, Sharma K K 2 and Sharma Parul

Ayurveda, the traditional medicine of India has emphasised on various modalities of treatments. This includes both the internal and external treatments explained for different diseases. “A fired building is best saved by pouring water”, in the same way tropical problems are successfully managed by tropical treatment rather than systemic treatment. Upanaha, poultice is a kind of topical application. It helps in reducing vatadosha, sheeta (coldness), shola (pain), sthambha (stiffness), gourava (heaviness). Pain medicine is one of the emerging areas of research and development. Upanaha is proved effective in the management of pain and other inflammatory conditions mainly of Locomotor System. An attempt has been made to collect references about upanaha from the classics of Ayurveda and reviewed systematically.

9

Authors: Beena M D1 *, Anjana L Siddapur2 and P Sudhakar Reddy3

Cancer is a dreadful condition and is one among the leading cause of death worldwide. The conventional methods of treatment include surgery, chemotherapy and radiotherapy according to the condition which is more expensive and with complications. Even though modern medicine made remarkable treatment protocol in the early stages of the cancer, but failed to improve the quality of life and increasing the life span of the 4th stage cancer patients. A diagnosed case of 4th stage of Lung cancer approached to our hospital and was treated with appropriate treatment modalities based on the principles of Ayurveda such as periodical purification therapy, symptomatic and anti-cancerous treatment along with rejuvenation therapy showed promising result in extending the life span to the expected median survival rate with improvement in the quality of life.

9

Authors: Swapna B Zerikunthe

The traditional Indian medicine called Ayurveda which originated thousands of years ago is still been widely practiced and famous as a first line of health care system. Ayurveda is opted as a first choice of initial health care method among people of India. The base of Ayurveda is it’s certain unique principle’s which makes it popular. The present paper elaborates the role of principles of Dinacharya, Rutucharya, role of Ayurvedic dietary principles, role of simply available medicinal plants, some kitchen spices and specially prepared mixtures called Rasayanas in prevention or primary health care. It also helps an individual to be in an equilibrium state of body, mind and spiritual elements. Also the role of Ayurveda in paediatrics, women’s health and in geriatrics is described. There is need of integration of Ayurveda and Allopath at Primary Health Care level is also strongly advocated.

9

Authors: Pushkar Singh Bhakuni1 *, Sanjay Kumar Singh2 and Shashi Kant Tiwari

Skin is the largest organ of the body and part of the integumentary system. All major skin disorders in Ayurveda are described under Kustha. Dadru is also a subtype of Kustha. According Acharya Charaka Dadru is a Pittkapha pradhan tridoshaj vyadhi affecting all age group of population. Kandu, Mandal, Raga, Pidika are the cardinal features of Dadru. Based on symptomatology Dadru is simulated with Tinea in modern perspective, which is superficial fungal infection affect skin, hair and nail. Incidence rate of Dadru gradually increasing day to day because of improper ahara-vihajra.The knowledge of nidana is helpful for proper diagnosis, prevention of disease and treatment also. The main objective of the study is to evaluate and analyze the etiological factors of Dadru Roga, for this purpose, an observational study was done on 40 patients of Dadru, based on demographic data, Aharaja,Viharaja nidana.

9

Authors: Kamath M

Rajata is kept in Loha Varga in Indian alchemy, the silver most commonly used for various properties are whiter and bright whereas Agrahya Rajata becomes yellowish red, rough and light. The use of metallic silver is an antimicrobial agent has long been recognized. Silver yields two key benefits: (i) they are broad-spectrum antibiotics (ii) At the nanoscale, silver exhibits unusual unfamiliar physical, chemical and biological attributes. Nanosilver means which are very minute then 100 nm and comprise of 15-20,000 silver atoms. Due to its antimicrobial property, nanosilver coatings using in special kinds of garments and coatings on different implants. NS Nano Silver has possessed anti-inflammatory activity and helps in the management of healing process of the wound, Nanosilver can be used manufacturing in better dressings for wounds, burns which helps in the rapid healing or repair of damaged cell process during wound.

10

Authors: Deepa C Patil1 and Veena G Rao

Diabetes mellitus is a leading cause of morbidity and mortality world over. It is estimated that approximately 1% of population suffers from Diabetes mellitus. The incidence is rising in the developed countries at the rate of about 10% per year, especially of type2 Diabetes mellitus, due to rising incidence of obesity and reduced activity levels. Madhumeha is caused due to Apathyaahara and viharasevana. While enumerating the chikitsa for Madhumeha all scholars have focused on the management of Madhumeha with a greater importance on Pathya. Ahara is said to be Mahabhaisajya, where one is not able to sustain life without diet even of endowed with medicine that is why the diet is said to be the great medicament by physician. In Ayurveda, pool of information is available in scattered form. In present day scenario, there is need to collect the scattered matter and it is to be reproduced with a scientific data base in front of the modern world.

10

Authors: Asha Malviya1 *Jyoti Rani2 and Vitthal G Huddar

Sciatica is considered as Gridhrasi in Ayurveda which is characterized by pain or discomfort associated with sciatic nerve. This disease very badly affects the quality of life of patient. Modern medicine has no permanent treatment for sciatica. Aim and Objectives: The aim of this study was to explore the Ayurvedic management including Raktamokshana, Shodhana, Shamana and Rasayana Chikitsa in Gridhrasi. Materials and Methods: It is a single case study. A 49‑year‑old female patient, came with complaint of difficulty in walking , severe pain in lower back region radiating towards right lower limb, numbness in right foot for past one and half year, stretching pain in left lower limb for past 3months, approached to Ayurvedic hospital where she was treated with Raktmokshana, Shodhana (Yoga basti) ,Shaman and Rasayana Chikitsa. The treatment was continued for 3 months. Results: Assessment was carried out during 2 months and satisfactory outcome came and overall quality of life of patient was significantly improved. Conclusion: The above mentioned therapy gives symptomatic relief in patients of Gridhrasi.

11

Authors: Dongre Sushma

Indian alchemy traditionally known as Rasshastra (science deal with processing of metals and minerals) is the strength of ancient Ayurveda treatment. Numerous alchemical texts were written in different era on Indian Alchemy. These books confer evidences that sole invention of this science come about in Buddhist period. Acharya Nagarjuna known as “Father of Iatrochemistry” was the first who discovered the metallurgy and the art of gold preparation from Mercury. As the whole world is looking forward to the remedies which heals and rejuvenate the body, Rasashastra medicine which is having curative and preventive aspect gives assurance of longer life and stability for achieving higher goals in the life. Nagarjuna was the great Buddhist philosopher and the most revered person after Gautam Buddha in Buddhism. He performed immense activities for the benefit of the Doctrine and human beings. He wrote many standard treatises on Indian alchemy viz. Kakshaputatantra, Rasaratnakara and Arogyamanjari etc. Vrinda and Chakrapani Datta are the other notable treatises of this period. Vrindmadhava is one who not only charted diagnostic techniques of diseases but also mentioned therapeutic uses of Rasushadhies. Use of Lohadhatu and Mandoor (Iron compounds and oxides) with plant based medicines are important inputs of Vrinda while on other hand use of Rasparpati in Grahani vyadhi(GIT disorders) was first discovered by Chakradutta. Use of Loha rasayana is also seen frequently in books by Chakradutta. So it can be concluded that Nagarjuna and his contemporaries have lifted this science of alchemy to the topmost position.

11

Authors: S Tameem Ansari1 *, Syeda Ather Fathima2 , Shivalingappa J. Arakeri3 , Mohasin Kadegaon4 and Geethanjali Hiremath5

Ayurveda is a Science of medicine which is based upon tridoshas, SaptaDhatus and Trimalas which are elaborated in detail in Samhitas. Sushruta mentioned that the existence of body is not possible without the presence of Vata, Pitta, Kapha and rakta and rakta plays an important role in entire surgical procedures. Therefore Rakta is considered as 4thDosha. There is a lot of confusion and uncertainty among the fraternity of Ayurveda whether to consider Rakta as fourth dosha or not. Here an attempt is made to Critical and Logical reasoning of the subject..

11

Authors: Shilpa Kotagi1 *, Suryanarayana Mudadla2 and Radhika Injamuri

BACKGROUND AND OBJECTIVES: Atopic dermatitis is the most common chronic relapsing skin disease seen in children. It effects 10- 30% of children worldwide and frequently occurs in families with other atopic disease such as asthma, allergic rhinitis and food allergy. Objective of the present study was to evaluate the effect of Kustaharakashaya tablet and Durvadya tail and comparing Kustaharakashaya Tablet and Durvadyataila with Hydroxyzine HCl with Clobetasol propionate. METHODOLOGY: 40 patients fulfilling the inclusion criteria of atopic dermatitis were randomly selected and divided into two groups each group contains 20 patients, namely Group A-Kustaharakashaya tablet and Durvadyatail, Group B -Hydroxyzine HCl syrup and Clobetasol propionate ointment. SOURCE OF THE DATA: Patients were randomly selected from outdoor patients of SJG AMC& Hospital, Koppal. Clinical signs and symptoms were given suitable scores according to their severity and were assessed based on pre and post test data gathered through predesigned clinical research proforma. The results having ‘p’ value <0.05 were considered to be statistically significant in this study. RESULTS: Complete or Marked relief was not observed in any of the groups. Moderate response, 60% was noticed in Group A, where as in 57% was seen in Group B. CONCLUSION: Based on observation and results concluded as trial drug i.e. Kustaharakashaya Tablet with DurvadyaTailahas a positive role in the management of Atopic Dermatitis in Children.

12

Authors: R Rakshith N N1 *, Shrinidhi R2 , Sudhakara Bhat3 and Chaithra Hebbar4

Agadatantra is one among the Astanga Ayurveda which deals with the vishachikitsa (Clinical toxicology). The visha (Poisoning) is dire condition which needs a fast anticipating action, if not leads to the irreversible changes. Visha (Poison) is classified into sthavara (stable-plant origin) and jangama (mobile-animal origin) visha. Sthavara visha is further classified into mahavisha (Potent poison) and upavisha (Subpotent poison). Vatsanabha is one among the potent mahavisha, currently known to mankind, used in the plenty of formulations. If accidently consumed or used in inappropriate methods, will cause diverse signs and symptoms leading to the life threatening conditions. Literatures of Ayurveda explain many methods of shodhana for vatsanabha (purification methods) which can be adopted following its judicial use. The essential chikitsa (therapeutic management) and pratyoushadha (counter medicine/antidotes) when poisoned by vatsanabha is also well explained. The current paper reports the exploratory review of the drug, its purification methods and antidotes thus screening the poisonous as well as its potential effects.

13

Authors: Chandrakar Yogita1 * and Kande Aradhana

In Ayurveda, twak vikara (skin disease) is caused due to imbalance of tridosha, but pitta dosha is involved in prime form. Pitta and rakta dhatu vridhhi kshaya is compliment to each other by Ashraya-ashrayi bhava. Lakshana of kushtha depends upon Dosha-dushya sammurchhana. Skin is one of the most defining aspects of our appearance and first barrier of protective mechanism. Skin diseases have been dealt under the Kushtha and kshudra roga and all types of Kushtha have been considered as Raktavaha srotodushtijanya vikara and Tridoshaja origin. Vicharchika is described under Kshudrakushtha in samhita texts. Lakshanas are Kandu, Pidika, Shyava, Bahustrava in Charaka. Lakshanas are Rajyo, Atikandu, Ruja,Rukshata in Sushruta. Vicharchika is mentioned in dominancy of different dosha by various acharyas. Kapha & Pitta, Rasa, Rakta, Mamsa, Swedavaha srotasa are key pathological factors involved in the Samprapti of Vicharchika. A similar clinical presentation of Vicharchika in modern dermatology is seen in Eczema, which is defined as a non-contageous inflammation of the skin when it has not involved any infection. In the 21st century, urbanization, science and technology had made our life better, fast and sedentary. Therefore, neither do we have time to think and act for healthy life nor to follow a proper Dinacharya and Ritucharya, this affects mansika bhava. Now a days, skin diseases are becoming a major hazard for mental health more than physical harm as it distributes the cosmetic harmony. Outside food is also a major cause of dietary incompatibility (Viruddha Ahara) which is a major cause of Vicharchika (eczema). According to management of Vicharchika the Ahara-Vihara which are having Kapha-pittashamaka and Laghu property are used for its treatment. In this article, an attempt has been made to study the Etiopathogenesis of Vicharchika (Eczema) and role of life style management and pathyapathya on this disease.

14

Authors: Shalinee1 *, Pravesh Tomar2 , Gyanendra D. Shukla3 and Shobhit Kumar

Artavakshaya is described in Sushruta Sutra Sthana during description of “Dosha Dhatu Mala Kshaya Vriddhi” and it is defined as Alpartava both in amount and duration with associated symptom of ‘Yathochitakala Adarshnam’ and ‘Yonivedana’. Aartavakshaya symptoms resemble with Hypomenorrhoea and Oligomenorrhoea based on their signs and symptoms described in the modern medical science. But in Artavakshaya, Acharya Sushruta mentioned Yoni Vedana which may resembles to dysmenorrhoea in modern text. Artavakahaya is the most prevalent associated clinical condition met in day to day gynecological practice especially in adolescent and young age group women. Present study was designed to establish an Ayurvedic management of Oligomenorrhoea & Hypomenorrhoea. The treatment given was JY-P Ghan Vati (Anubhoot Yoga) with Krishna Til Kwath and Shatpushpa (Anethum sowa)Churna after Koshtha-Shuddhi. Aims & Objectives: -To study the efficacy of JY-P Ghan Vati with Krishna Til Kwath the management of Artavakshaya. To study the efficacy of Shatpushpa (Anethum sowa)Churna in the management of Artavakshaya & to compare effect of both drugs in the management of Artavakshaya. To observe adverse effects of drugs according to complains of patients if any. Material & Methods:-60 clinically diagnosed patients of Artavakshaya (Oligomenorrhoea and Hypomenorrhoea) were randomly selected from OPD/IPD Dept. of Prasuti Tantra & Stree Roga, Rishikul Campus Haridwar and were divided into three groups of 20 patients each. In Group-A JY-P Ghan Vati with Krishna Til Kwath, In Group-B Shatpushpa Churna and in Group-C JY-P Ghan Vati with Krishna Til Kwath and Shatpushpa Churna were given for three consecutive menstrual cycles. Results: - All the three groups shown statistically significant results in treatment of Artavakshaya but on inter comparison of groups, Group-C (JY-P Ghan Vati with Krishna Til Kwath+ Shatapushpa Churna) showed better results than Group-B and Group-A in all subjective parameters, on the basis of percentage relief.

15

Authors: Sandip Baheti1 *, Amit Gajarmal2 , Anjali Prasad3 and Dattatraya Dighe4

In December 2019, China had reported a new respiratory tract infection which occurred due to infection caused by coronavirus and the diseased was later named as COVID19. All modern physicians along with all healthcare faculties worldwide got engaged in the search of effective medicine against Covid19. In India under preventive and prophylactic treatment, Ministry of AYUSH suggested a combination of four traditional medicine named Tulasi (Ocimum sanctum L.), Twaka/Dalchini (Cinnamom umzeylanicum BL.), Shunthi/Sontha (Zingiber officinalisRosc.) and Maricha/ Kali Mirch (Piper nigrum L.) named as AyushKwatha which is said to be used in the form of decoction. Each herb was used as a traditional medicine as single drug and in different formulations. The current article tries to explain the therapeutic value of these four Ayurveda herbs as a health promoter and immunity booster. Also, it gives strength to the respiratory system. AyushKwath may play a key role in prevention of diseases as well as in management of autoimmune diseases..

15

Authors: Simi Scaria1 *, Rajalaxmi M G2 and Padmakiran C

Vamana karma is one among the panchakarma therapy considered as the best therapy for the elimination of vitiated kapha and kapha samsrista dosha. Psoriasis is a long standing auto immune disease characterized by patchy skin lesions which is typically red in colour associated with itching and scaling. Psoriasis with its signs and symptoms has similarities with kapha pradhana kustha. In this present clinical study, Kutajaphaladi yoga was used to assess the efficacy of vamana karma in Psoriasis. Assessment of psoriasis was done with ‘psoriasis area severity index’ (PASI), Auzpitz sign & Candle grease sign. This study showed statistically significant result with reduction in PASI score (P < 0.000). The study concluded that Kutajaphaladi yoga was effective in the management of psoriasis. More researches on comparison are needed to be conducted with other emetic drugs of higher safety and efficacy.

23

Authors: Jasminbegam B. Momin1 *,V E Gogate2 and P V Kulkarni

Ayurveda the full-fledged system of medicine offers wisdom and practices for living a healthy life. It gives utmost importance to personal health by stating ‘aarogyam moolam uttamam.’ This can be achieved by following proper dincharya, ritucharya and sadvritta along with healthy dietary habits. The ancient ayurvedic samhitas have explained different pathya kalpanas under the kritanna varga like manda, peya, vilepi, yavagu, yusha, etc. These are important in the field of prevention of health where different dravyas are used for maintaining and sustaining the living body. In therapeutics also many pathya kalpanas are described as a vehicle for shodhana and shamana formulations. But still these therapeutic measures remain neglected because of reluctant approach towards unfamiliar methodology of these pathya kalpanas. This article aims to review the detail concept of pathya kalpana in order to explore the scientific approach towards ancient dietary regimen to ensure the healthy life.