Ankylosing Spondylitis (~ Amavata): A Case Study
Authors: Rajesh Jain, K.S.Girhepunje, Anupam Srivastav and J.S.Tripathi
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Ankylosing spondylitis (AS) is a multifaceted, potentially devastating disease that is insidious in
onset, making progress to radiological sacroiliitis over several years. Patients with symptomatic
AS drop productivity owing to work disability and redundancy has a considerable use of
healthcare resources, and compact quality of life. The pathogenesis of AS is poorly understood.
AS belongs to a group of rheumatic diseases known as the spondylo-arthropathies, which showsa
strong connection with the hereditary marker HLA-B27.Immune mediated mechanisms involving
human leucocyte antigen (HLA)-B27, inflammatory cellular infiltrates, cytokines, and genetic
and environmental factors are considerable to have key roles. The detection of sacroiliitis by
radiography, magnetic resonance imaging, or computed tomography in the presence of clinical
manifestations is indicative for AS, although the presence of inflammatory back pain plus at least
two other characteristic features of spondyloarthropathy (for example, enthesitis and uveitis) is
highly predictive of early AS. Non-steroidal anti- inflammatory drugs (NSAIDs) plays the major
role in the treatment of this situation; however, they have serious adverse effects and have
limitations for an extended therapy. Hence, there is a need for drugs having good efficacy with
low toxicity in this devastating disorder. From the Ayurvedic perspective, the disease can fall
under amavata, which may be successfully managed when intervention is started in its early
stages. The whole management includes Deepan, Pachan and Vatanuloman described in the
chikitsa sutra of Amavata. Shamana treatment with aamavatari rasa, rasonpind, sanjeevanivati,
rasnasaptakakwatha and Simhanadaguggulu has been found useful in restriction its progression.
This article presents a solitary case report in which these treatments achieved significant success.