International Journal of Ayurveda and Pharmaceutical Chemistry

4

Authors: Subha Ganguly

Purification in Ayurvedic treatments includes elimination of environmentally toxic substances such as polychlorinated biphenyl (PCB's) and pesticides from the body system without the risk of any side effect. Panchakarma therapy in modern Ayurvedic system of medicine finds an important implication in this regard.

6

Authors: Satender Tanwar, Shailaja S.V and Kiran M. Goud

Chemonucleolysis is a non-surgical treatment for a bulging disc that involves the injection of an enzyme called chymopapain into the vertebral disc with the goal of dissolving the inner part of the disc, the nucleus pulposus. The chymopapain extract from the papaya plant having property to dissolve the property of dissolves the dislocated disc causing compression on the spinal nerve and gives the symptomps of sciatica. Chymopapain is a proteolytic enzyme isolated from the latex of papaya (carica papaya). It is a medication used to treat herniated lower lumbar discs in the spine. The treatment seemed to offer a less invasive, lower-cost alternative to surgery while achieving comparable success. Although many patients experienced excellent outcomes, chemonucleolysis with chymopapain was found to cause serious side effects at a higher-than-expected rate. The nonspecific enzyme digested structures in addition to the disk nucleus, leading in the worst cases to hemorrhage, pain, and paralysis. In some patients, chymopapain triggered serious allergic reactions, including fatal anaphylactic shock. Serious side effects from the use of chymopapain include anaphylaxis, paralysis of the legs or death. Due to the above reasons twenty years later—in January 2003—the FDA halted the sale and distribution of chymopapain in the United States. After taking above concept in due consideration the oil can be extracted from the papaya plant and can be tried in the form of kati basti and kati pichu to get the better result in case of IVDP and prove to be less invasive, cost effective and one of great achievement in the field of Ayurvedic medicine if come out with successful results. Hence, there is scope for the above said conceptual study to make it EBM (Evidenced Based Medicine) and new advancement in the field of medicine.

8

Authors: Vidhi Bapna (Kumath)

During last few years the graph of people suffering from diabetes is growing fast .The disease is very dangerous as it takes over the important vital organs of the body. All the medicinal systems globally are trying to fight the ailment. Role of medicinal plants in the treatment of diabetes can be very promising. Many medicinal plants have been scientifically proved to have hypoglycaemic effect. This paper discusses a lesser known medicinal plant ‘Withania coagulans’ which have anti diabetic potential.

13

Authors: Neha G. Tank

Pancolitis is a very severe form of ulcerative colitis. Pancolitis is a kind of inflammatory bowel disorder (IBD) that affects the entire internal lining of the colon. The precise causes of this inflammatory disorder are unclear, although physicians assume that autoimmune diseases and genetic predispositions might play a role in its progress. An individual with such a condition is expected to experience abdominal pain, recurrent episodes of bloody diarrhea, and persistent fatigue. Long-standing ulcerative colitis increases the risk for colon cancer. The treatment of ulcerative colitis involves medications and/or surgery. Since inflammatory bowel disease is currently an area of active and productive research, new treatments are anticipated which, it is hoped, will be of value in ulcerative/pan colitis. In such a scenario Ayurveda can be a ray of hope as it has some good remedies to cure this disease. In Ayurveda, Pancolitis can be corelated with Raktaj Atisaara and treated accordingly. The present study describes a complex case of Pancolitis where drugs like Hingvashtaka Churna, Shatavari Ghrita, Panchamruta Parpati etc along with Maatra Basti not only stopped the bleeding in stool but ,decreased the frequency of stool to 2 per day Panchamruta Parpati was used in increasing dose and the toxicity study is also done.