International Journal of Pharmaceutical Chemistry and Analysis

27-29

Authors: Saraswati Prasad Mishra, Anil Kumar Sahu, Pankaj Kashyap, Deepak Dash, Koushlesh Mishra, Rupesh Bhoi.

Nowadays there is increased prevalence of co-morbidity of hypertension and diabetes. Hypertension has become such a bigger health problem as it does not show any manifestation of it until it gets seriously complicated. High blood pressure is the major cause of premature deaths which comes around 7.6 million (about 13.5% of the global total) worldwide. Non-insulin dependent diabetes mellitus (NIDDM) is a global pandemic. By 2025 it is been projected that around 300 million people will have NIDDM worldwide. WHO projects that diabetes will be the 7th leading cause of death in 2030. Diabetes and Hypertension often termed as co-morbid disease as there is greater tendency of both the complication occurring together. The prevalence of hypertension among T2DM patients varies across countries and is reported to range from 20.6% to 78.4% in the Southeast Asian region, and 9.7% to 70.4% in the African region, in India it is 6.4% to 55%. To reduce the complications of diabetes in co-morbidity, hypertension should be in the range of 130/90 mmHg for that apart from allopathic system of therapy ayurvedic and unani system of therapy and certain lifestyle changes can be undertaken as these systems do not have drawbacks such as side effect, long duration treatment, and high cost therapy.

35-36

Authors: Kirti Rani.

Bovine serum albumin-egg albumin-multiwalled carbon nanotubes (BSA-EA-MWCNTs) submicron hybrid compositewas prepared by using suitable organic solvent and emulsifier as surface modifier. The prepared submicron hybrid composite was subjected for their size characterization by using scanning electron microscopy (SEM) under optimal conditions. This albumin based hybrid submicron complex was found to have particle size up to 2micrometer. This prepared BSA-EA-MWNCTs submicron hybrid composite can be further used as good biosensing interface because of using electrochemical active MWNCTs in the proposed fabrication which might be considered for carrying out various clinical analytical approaches and pharmaceutical applications.

43-45

Authors: Kirti Rani.

Azadirachta indica is rich source of alkaline phosphatase and alkaline phosphatase are known for their industrial application in food and pharmaceutical industries. The extracted alkaline phosphatase was encapsulated into biochemically active egg albumin and BSA nanoparticles with butanol and glutaraldehyde. Achieved encapsulation was 69% when egg albumin (EA) used and 85% was observed when bovine serum albumin (BSA) was used. Characterization of prepared albumin nanoparticles was done by scanning electron microscopy (SEM). Observed size of enzyme loaded nanoparticles was reported up to 80nm when egg albumin was used and up to 100m when bovine serum albumin was used for encapsulating the Azadirachta indica alkaline phosphatase.

51-53

Authors: Akansha Budakoti, Upasana Sethi Ahuja, Siddharth Srivastava, Akshay Rathore, Parul Tikoo Dhar.

Introduction: Since the dawn of civilization, mankind has been plagued by pathogen and its ensuing disease process and to overcome the outcome of the disease, various medical therapies have been formulated over the time. With the evident of medical therapies various side effects of the drugs used have come up and to overcome those side effects complementary and alternative medicine (CAM) has evolved. Aim: The goal of this study is to examine the relationship between the disease condition and the usage of the CAM therapy among the general population. Materials and Method: The CAM encompassed number of therapies so, the survey instrument is a self modified designs questionnaire based on previous studies carried out in the literature. Questionnaire will be filled by the patients visiting a dental school with any dental problem. First part of survey instrument incorporates questions regarding demographic characteristics. While the second part of survey consisted of 17 medical /dental conditions for which the patient visited a dental college and have approached for the management of these diseases. Results: More than half respondents were females(53.8%)with the common age group of 61-80 year old. The most frequent oral health problem was tooth ache (70.3%), followed by other problems and most frequently used CAM therapy was herbals. Conclusion: A large proportion of dental patients reported use of CAM- therapies .Gender and the age group was significant factor. A more refined instrument should be used for the future studies for understanding how CAM usage is associated with dental problems.