Journal of Science and Applications: Biomedicine

1-4

Authors: Christina L. Ross, Brandi Bonfert, Leona Smith, Seon Yeong Jeong and Benjamin S. Harrison

Oxygen diffusing biomaterials provide a controlled release of oxygen while minimizing moisture loss, which is a major complication in the application of topical oxygen to wounds. We have devised an oxygen releasing biomaterial using a combination of sodium percarbonate (SPO), calcium peroxide (CPO), and polycaprolacetone (PCL) to supply a quick diffusion of oxygen delivery to hypoxic cells. Results indicate oxygen levels released via treatment enhanced cell viability despite hypoxic conditions as compared with normoxic environmental control.

32-35

Authors: Cong Li, Jin Wu, Min He, Qin Zhou

The aim of this paper is to study the relativity between oxidative stress and cervical squamous cell carcinoma (CSCC) . Cervical cancer and healthy crowd cervical tissue were collected, and their content of Peroxiredoxin 6 (PRDX6) was measured and compared with Western Blot. PRDX6 was highly expressed in human CSCC tissue compared with healthy control, indicating that PRDX6 is a sensitive oxidative stress factor for the detection of cervical cancer.

28-31

Authors: Xiaohong Chen, Kun Chen, Xianzhu Li, Bo Cheng

Objective: This research investigated the effects of active and passive music therapy on the psychology with prepuce cerclage. Methods: 89 child patients were randomly divided into the treatment group and the control group. Pains, fears and compliances of two groups were compared. Results: Patients in the treatment group felt less pain and anxiety than the control group. For compliances rated by nurses and surgeons, the treatment group performed better than the control group. Conclusion: Active and passive music therapy could effectively reduce pains, psychology of fear, and improve compliance of children with prepuce cerclage.

26-27

Authors: Deying Zhang, Xing Liu, Dawei He, Tao Lin, Xuliang Li, Guanghui Wei

We presume that in addition to hormone therapy and operation of orchiopexy at proper age, application of vitamin A to patients with cryptorchidism at the age of 2~3 months and 4~5 years may be benefit to preventing male infertility and testicular cancer by promoting the spermatogonia differentiation and initiating meiosis.

20-25

Authors: Deying Zhang, Danian Qin, Guanghui Wei, and Yuanyuan Zhang

Urothelial cells (UCs), with functional tight junctions, act as a barrier of urinary tract, autologous UCs provide a cell source for tissue engineering in urology, but healthy UCs might be not available under the circumstances of malignancy, infection and stones in urinary tract system. Mesenchymal stem cells (MSCs) from various tissues, such as bone marrow, adipose tissue, amniotic fluid and voided urine are investigated on urothelial differentiation for urinary tract regeneration. In this brief review we discussed urothelial differentiation of MSCs, especially urine derived stem cells, which provide potential application in urinary tract epithelial reconstruction.