European Journal of Medicine

3-20

Authors: Igor Akszjonovics, Ignat Ignatov

This paper presents the results of evaluation of possible biophysical methods and approaches for registering of various non-ionizing radiation (NIR) wave types of the human body in the electromagnetic range after the influence of device ABIEM (Akszjonovics, 2006). Many types of NIR (electromagnetic waves, infrared radiation, thermo radiation, bioluminescence) emitted from the human body were reviewed. In particular the results on of spontaneous biophoton emission and delayed luminescence from the human body are submitted along with infrared thermography (IRT) results. It was shown that 1 cm2 of skin generally emits 85 photones for 1s. The intensity of biophoton emission ranges from 10−19 to 10−16 W/cm2 (approx. 1–1000 photons.cm-2.s-1). The specific photon emission from part of the human thumb was detected as a spectrum of various colors after influence of ABIEM with the method of Color coronal spectral analysis (Ignatov, 2007) on a device with an electrode made of polyethylene terephthalate (PET hostafan) with applied electric voltage 15 kV, electric impulse duration 10 s, and electric current frequency 15 kHz. It was established that photons corresponding to a red color emission of visible electromagnetic spectrum have energy at 1.82 еV. The orange color of visible electromagnetic spectrum has energy at 2.05, yellow – 2.14, blue-green (cyan) – 2.43, blue – 2.64, and violet – 3.03 eV. The reliable result measurement norm was at E ≥ 2.53 eV, while the spectral range of the emission was within 380–495 nm and 570–750 nm±5 nm. Also were estimated some important physical characteristics (energy of hydrogen bonds, wetting angle, surface tension) of water by the methods of non-equilibrium energy (NES) and differential non-equilibrium energy (DNES) spectrum of water (Antonov, 1990; Ignatov, 1998), that helps understand in general how electromagnetic radiation interacts with water and establish the structural characteristics of water.

30-34

Authors: Naina Mohamed Pakkir Maideen

Acetaminophen (Paracetamol) is the most frequently used Over-The-Counter (OTC) antipyretic and analgesic drug, worldwide. The metabolism of Acetaminophen is mediated by phase II reactions (UDP-glucuronosyl transferases (UGT)-mediated glucuronidation and sulfation) and phase I oxidative reactions mediated by Cytochrome P450 (CYP) enzymes including CYP2E1 and CYP1A2. The drugs inducing CYP2E1 and CYP1A2 enzymes and the drugs inhibiting UDP-glucuronosyl transferases (UGTs) may increase the exposure of NAPQI resulting in elevated risk of hepatotoxicity. The risk of acetaminophen-associated hepatotoxicity might be elevated due to concomitant use of certain medications including Isoniazid, Antiepileptic drugs, Tyrosine kinase inhibitors and Alcohol. Acetaminophen may increase the international normalized ratio (INR) by potentiating the anticoagulant effect of warfarin. To prevent possible adverse drug interactions, the prescribers and pharmacists must discuss with their patients about the use of OTC Acetaminophen.

45-56

Authors: Reneta Toshkova, Elissaveta Zvetkova, Ignat Ignatov, Georgi Gluhchev

The paper describes the results of a pilot study aimed at the investigation of the influence of catholyte (electrolyzed alkaline water) on the development of tumors. In the experiments solid Graffi tumor was transplanted subcutaneously in the back of the experimental group of Golden Syrian hamsters. Tumor appearance and growth were registered every day. Blood parameters were measured on the 10th and 25th day after transplantation and blood smears were prepared. Hamsters treated with catholyte developed tumor with some delay compared to untreated (drinking tap water) ones. Also, the tumor growth was slow and the survival rate was increased. The analysis of blood parameters and cell morphology has shown significant differences in the value of some hematometric parameters and morphological changes of some blood cells. The obtained results suggest about the beneficial influence of catholyte and the possible use of it as a supporting non-invasive therapy of cancer diseases.