FUNCTIONAL AND NEUROIMAGING DIAGNOSIS IN THE GEMIMEGALENTSEFALY DIAGNOSIS AND SPECIFIC EPILEPTIC SYNDROMES
Authors: Mikhailova N.V., Savinov S.V., Akchurina I.E., Grebenyukova I.V., Utebekov Z.E., Sitnikov I.Y., Abedimova R.A., Esimova G.N., Sinitsina T.N.
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Gemimegalentsefaly - serious malformation of the
brain, which always combined with severe symptomatic
forms of epilepsy. The latter, in turn, aggravate and
worsen the prognosis for the child. Impossible to
achieve a stable positive result against the background
of selection of anticonvulsant therapy.
In SVS Laboratory study of epilepsy, convulsions
and family monitoring after V.M.Savinova observed
a child with congenital malformation of the brain -
gemimegalentsefaly. Parencephaly put at prenatal
diagnosis by ultrasound, and then confirmed by CT
scan of prenatal. After the birth repeatedly held video
EEG monitoring with the registration period of sleep and
wakefulness and including attack period, neurological
examination, MRI diagnosis (1,5 Tsl). Prescribed
anticonvulsants combination, with low effect results.
Underwent surgery –functional vertical gemisferotomy
in the left side. Postoperatively, seizures were not
As a result, our conclusions were drawn:
Treatment of choice is surgical patients while taking
AEDs. Surgical treatment is based on resection of the
affected hemisphere to provide the best compensatory
capacities of the brain due to a healthy hemisphere.
Early diagnosis and a decision on operative
treatment is great prognostic value. The sooner an
operation will be made, the better the work of adaptation
mechanisms of the body.
The main indication for postponing surgery may
serve as a small child’s weight due to an increased risk
of breaking bcc intraoperative conditions.
Key words: gemimegalentsefaly, prenatal
diagnosis of congenital malformations of the brain,