INTERNATIONAL JOURNAL OF CHEMICAL AND PHYSICAL SCIENCES

24-30

Authors: Prof. V. C. Renge, Alok K. Meshram, Pavan K. Badukale

There are economic and environmental benefits when we recover solvent for reuse, especially when expensive solvents and large volumes are involved. An industry has been recovering solvents for many decades at facilities. Solvent recovery is a routine practice in the pharmaceutical industry when it is technically and economically viable for the particular waste stream. Various waste streams being generated at an API (Active pharmaceutical ingredient) synthesis plant. The goal is to investigate those streams that could not be most easily recovered with traditional separation and purification processes. As a first step in that analysis, the recovery of toluene & methanol solvent from a waste stream in the synthesis was considered. Here it is very difficult to separate this complex mixture, so that for separation of this complex mixture azeotropic distillation method is to establish by using the water and an entrainer.