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EVALUATION OF PULMONARY FUNCTIONS IN HYPERTENSIVE PATIENTS TAKING ANTIHYPERTENSIVE DRUGS.
Authors: Dr. Rizwan Qurershi, Dr. Paresh Prajapati *, Dr. Saurin Sanghavi **, Dr. Sajid Saiyad***, Dr. Jwalit Mehta**** Dr. Anju Mehta*****
Number of views: 465
Abstracts: Background and Objectives: Chronic hypertension has been found to be associated with
altered Pulmonary Function Tests (PFTs). However, alteration in PFTs and their association with
antihypertensive drugs has not yet been established. Therefore, the present study was undertaken to
find out relationship altered PFTs in hypertensive patients on an antihypertensive drugs for more
than one year. Methods: Hypertensive patients were taken from OPD of Quresh Medical Trust,
Ahmedabad and further divided into 2 groups, case group (n=50) those who were taking
antihypertensive drugs for more than one year and control group (n=50) those who were not taking
any antihypertensive drugs. PFT parameters (FVC, FEV1, PEFR & MVV) were studied in both the
groups by using spirometer (Computerised Spirometer GMS-HELIOS 702).Results: The findings of
Pulmonary Function Tests showing that FVC,FEV1, PEFR & MVV all were reduced in case group
compared to control group and the difference was statically significant (p<0.01)Interpretation &
Conclusions: Similar to earlier studies done in India and abroad we also found an impairment of the
lung functions in hypertensive patients taking long term antihypertensive drugs especially Beta
blockers1
. So, the antihypertensive drugs should chose according to the status of the individual
patients. Antihypertensive drugs (Thiazide diuretics, calcium channel blockers, newer beta1 blockers)
which have less effect on airway functions are the drug of choice in hypertensive patients having
airway dysfunction.2