A correlation between thyroid hormone profile and physical parameters in normal person
Authors: Jitendra Patel, Jasmin Parmar, Anita Verma, Pratik Akhani.
Number of views: 295
Introduction: The aim of the study was to correlate the thyroid hormone profile with the age, height, weight, body mass index (BMI), with body fat percentage (BF%) in apparently healthy person.
Materials and Method: 84 normal subjects were included in the present study. In thyroid hormone profile S. TSH, Total S. T3, and Total S. T4 were estimated by lumax chemiluminescence immunoassay strip reader in the laboratory. Height, weight and BMI were recorded by standard method and BF% was calculated by the formula. Analysis was done by SPSS software.
Result: Of 84 subjects, 39 were males and 45 were females. The correlation coefficient of thyroid hormone profile: For S. TSH (r=+0.261, p=0.02), (r=+0.064, p=0.57), (r=+0.330, p=0.00), (r=+0.368, p=0.00), (r=+0.387, p=0.00); For S. T3 (r=-0.299, p=0.01), (r=-0.208, p=0.06), (r=-0.447, p=0.00), (r=-0.377, p=0.00), (r=-0.257, p=0.02); For S. T4 (r=-0.086, p=0.44), (r=-0.174, p=0.11), (r=-0.365, p=0.00), (r=-0.297, p=0.00), (r=-0.072, p=0.52) with age, height, weight, BMI and BF% respectively.
Conclusion: The S. TSH shows significant positive correlation with age, weight, BMI and BF percentage. While S. T3 shows significant negative correlation with age, weight, and BMI and BF percentage and S. T4 shows significant negative correlation with weight and BMI. That suggests the physical parameters also play an important role to determine the thyroid function, as thyroid hormone play an important role in the metabolism of almost all the cell of the body.