Journal of Advances in Molecular Biology

8

Authors: Yi Zhang, Zhihai Mao, Yuyang Hua, Shicheng Gao, Shenghan Lai, Jun Wang

Until 2016, the population living with HIV is 36.7 million. Though WHO set the goal to end HIV/AIDS, it is very challenging to stop HIV acquisition in 12 years due to insufficient of medical, economic, social and legal supports. Men who have sex with men (MSM), transgender people, sex workers, and drug users are traditionally classified as the key infected population. Recently, HIV infection in pregnant and breastfeeding women has caused more attention, for HIV hurts two generations in this case. Pre-exposure prophylaxis (PrEP) has been evaluated to be an efficient tool to reduce HIV infection among high-risk population. In this paper, we reviewed the most recent progress of PrEP application in these critical populations who are at substantial risk of HIV acquisition. We also discussed challenges and solution for better prevention of HIV/AIDS.