Herald of Almaty State Institute of Advanced Medical Education

6-12

Authors: Kurmanova A.M., Dzoz L.S., Bazylbekova Z.O., Utemeva Zh.A., Kravtsova N.V.

The article gives current views of the role of immune mechanisms of pregnancy complications, particulary preeclampsia. whether immunological assays can be used to diagnose and predict impairments of pregnancy. key words: preeclampsia, pregnancy, placentation, vascular endothelial factor of growth.

17-20

Authors: Abdurazakov U.A., Nechaev V.I.

The paper reviews literature on "short leg syndrome." presented definition, prevalence and etiology, as well as the clinical significance threshold at this syndrome. key words: short leg, limb shortening.

24-28

Authors: Aldasheva M.A.

The characterization of modern vital and nonvital methods of pulp therapy for primary and immature permanent teeth was presented in the article. the unified approach for terms and classifications choice are needed for purpose of improvement the extensive caries diagnostics and treatment.

33-35

Authors: Umeshov A.U., Imanbayeva M.B.

The clinical experience of treatment the female patient with uncommon case of foreign body -gigantic trichobezoar in stomach and duodenum was reported in the article. the clinical presentations, methods of diagnostics and surgical operation results were described.

40-43

Authors: Pronina Ye.N., Dovbnya Yu.N., Yeroshenko G.A.

The mucosa of anterior wall of frontal sinus of people of both gender, aged from 22 to 86 yrs, died for the reasons not associated with the paranasal sinus pathology, served as morphological material for the study, carried out in compliance with international standards of conduct of biological examinations. it was established that compound alveolar tubular glands are located in the submucous base of human frontal sinus mucosa. the acines and duct system is formed by the cylindrical cells and small cambial epithelial cells. migrant cells, i.e., macrophages and lymphocytes have been constantly found in the periacine and periduct connective tissues. the majority of mastocytes were characterized by the central position of nucleus, indicating about the predominance of heparin, included in the secretory granules.

48-52

Authors: Toybayeva G.T.

The correct and quality filling of medical record shows the professional level of doctor, is inalienable part of curative process and one of major duties of treating doctor. work with a medical record begins from the moment of appeal of patient in a policlinic and reflects validity of all stages of diagnostics; treatment and prevention ofdental diseases, the flow of pathological process and efficiency of the conducted events allow to estimate. except it, a medical record, being a legal document, becomes a basic source, defining the decision of legal questions, touching responsibility of doctor and patient.

56-58

Authors: Sarsenbayeva G.E.

In the article the contemporary facts of literature about using conform, therapy in antitumor treatment of cancer patients was shown. it was shown high clinical effective using the conform therapy in antitumor treatment of cancer patients.

62-66

Authors: Kurmanova A.M., Dzoz L.S.

It was found that in patients with high CD16+ lymphocytes level the activation markers HLA-DR+ and CD95+ expression levels are reliably higher than in the control group, and CD25+ expression levels are also higher compared to 1st group.CD95+/CD16+ index will be used, if its values are less than 0.8 on the background of CD3+, CD4+ decrease, interferon inductors will be prescribed, if the index value is 0.9 to 1.29 - interferon preparations, if the index value is more than 1.3 - interleukin-2 preparations.

9-11

Authors: Akhmetbayeva A.K., Avtushko S.V.,Yanchenko A.A., Akhmetbayeva A.B.

The use of paramagnetic contrast agent Primovist (Gadoxetate disodium) can significantly enhance the ability of MRI diagnosis of focal liver formations, to assess the functional state of the liver and biliary system.

18-23

Authors: Devyaltovskaya M.G.

The assessment of psycho-neurological functions development level was conducted and antibodies to nerve tissue proteins in blood serum were determined in 318 children under 1 year old with consequences of prenatal and perinatal lesions of brain. Children had the following diagnoses: G 80 Infantile cerebral paralysis or high risk of its development, R 62 Absence of expected normal physiological development. Prominent negative correlation was determined between psycho-neurological functions development level and idiotypic and antiidiotypic antibodies to S100 proteins in blood serum, glial fibrillary acidic protein, myelin basic protein, nerve growth factor. Increased concentrations of antibodies to neurospecific proteins show neurodestructive changes in brain substance and associated with motoric and psychic dysfunctions.

28-31

Authors: Kashperuk-Karpyuk I.S., Olijnyk I.Y.

In order to determine patterns of development of vesico-urethral segment in fetuses and newborns, its microscopic signs the complex of methods of morphological investigation the ranges of anatomical variability of the pelvic urethra and vesicourethral segment in fetuses and newborns, male and female has been established, the critical periods of their development has been determined, which will greatly assist in the early prenatal diagnosis of malformations of the bladder and urethra and timely surgical correction.

36-40

Authors: Alibayeva K.M., Berdiyarova N.A., Mukhamedzhanova N.K., Maymakova A.M., Nurakhova A.D.

Described many years of experience using the definition of C-reactive protein in patients with inflammatory response in terms of children's hospital and the Hospital for Infectious Diseases. Describes methods for determining the comparative characteristics of C-reactive protein and procalcitonin

44-47

Authors: Pronyaev D.V.

The article deals with the investigation of peculiarities of the structure and topography of the uterus in the beginning of the fetal period of development. There is a conclusive evidence that the causes of diseases of the female internal reproductive organs are mostly formed in the prenatal period of human development. However, certain congenital defects are resulted exactly from perinatal morphogenesis. By means of adequate methods of morphologic examination the uterine structure was studied on 30 samples of fetuses of 4-6 months of development. The uterine fundus of 4-month fetuses was found to be characterized by the following shapes: flat - 2 cases, convex - 1 case, vallate - 5 cases, tuberculous - 2 cases. An even distribution of the uterine fundus shapes found is seen in 5-month fetuses: tuberculous shape - 3 cases, vallate - 3 cases, flat - 2 cases, and convex - 2 cases. A flat shape of the uterine fundus prevailed in 6-month fetuses (7 out of 10). There were one of each case of vallate, tuberculous and convex found. Morphologically the shape of the uterine fundus changes in the second trimester from a vallate one on the 4th month of development to the flat one on the 6th month.

52-55

Authors: Teleuova T.S., Bezborodova E.A., Kubashev A.E., Amralin S.E.

Oftaquix without conservants is a powerful antibacterial agent of the fluoroquinolone class with broad-spectrum bactericidal activity. It suppresses the phenomenon of conjunctivitis in infants and young children age using 4 times per day for 4-5 days. When using the drug was not observed local and general toxic-allergic reaction. Therefore we recommend to use widely Oftaquix without conservants in the daily work of ophthalmologists.

61-65

Authors: Chuakova M.M.

HIV infection accelerates the course of tuberculosis, resulting in higher mortality in co-infected patients and increases the risk of progression to active ТВ. A large number of the 2 billion people with latent tuberculosis, living in regions with high HIV prevalence, where HIV infection turns latent tuberculosis in a time bomb for the development of tuberculosis in general. As a consequence of rapid progression, mortality is significantly higher in co-infected patients, compared with those who only have tuberculosis. Most of these deaths occur before treatment begins, or during the early months of therapy. In HIV-infected patients TB treatment is often complicated by biological factors, such as the side effects of drugs or immune reconstitution syndrome, as well as socioeconomic barriers. Expanding education and prevention programs aimed at dual infection within the existing infrastructure systems to combat tuberculosis and HIV is an initial step to reduce the load of these diseases. The main step in response to the overlapping epidemics of HIV and tuberculosis is to improve the detection of tuberculosis among people living with HIV, as well as the provision of HIV testing and counseling to all patients with tuberculosis.

69-72

Authors: Sarsenbayeva G.E.

Kazakh research institute of oncology and radiology In the article the contemporary facts of literature about using radiation therapy in complex and combined treatment of the cancer patients were shown. High clinical effectiveness of using the contemporary radiation therapy in antitumor treatment of cancer patients was shown.

77-78

Authors: Chormanova R.R., Bainazarova A.A., Gerieva M.M., Shardarbekova D.D., Kuvatova A.T.

This article shows the results of hysterosalpingography used in digital X-ray diagnostic in clinic on gynecology opens up opportunities for timely treatment of patients, improving quality of life.

81-86

Authors: Shklyar A.S., Sazonova O.N., Barchan G.S., Cherkashyna L.V., Babiy L.N.

The research has been carried out within the comprehensive program of obtaining, accumulation and analysis of results using the common conventional and novel techniques. Material of research was the results of direct anthropometry of about 1300 people divided on the basis of the ontogenetic period. Anthropometric research is executed proceeding from V. V. Bunak's chart and meant definition of the general (growth, weight, body surface area), the partial sizes of a human body (longitudinal, volumetric, cross, sagittal) and a skin fat fold thickness. The saved-up results made the reference database which results of development became a basis of the statistical analysis which fragment is given in this article, as well as number of the advanced development. In anthropometry, using the caliper on the back of the shoulder (d1, mm.) measurements were performed at lowered hand in the upper third of the arm triceps, close to its inner edge (the result is recorded on the vertical axis), under shoulder-blade (d2, mm., measurements are performed under the lower angle of the scapula, in an oblique direction: from top to bottom, inside out ) and the side (d3, mm. fold, that measured above the iliac crest (the result is recorded on the vertical axis), on the front surface of the shoulder (d4, mm. it measured in the upper third of the inner surface of the upper arm biceps, in vertical direction). Mean thickness of fatty folds index was calculated using the formula: F1=1,14-0,06xlog2(d1+d2+d3+d4), and general thickness: F2=d1+d2+d3 and determine the absolute amount of fat component (M^) with formula MFA=100x(G0/F1-G1). Further, the evaluation performed by BMFC endomorphic index (MFB ), which is defined by the formula M?|a=G2+G3xF2-G4xF22+G5xF23, considering age and sexual coefficients (G0-G5) and variability (SD) of an endomorphic indicator (MFB±SDFB) and absolute amount of fatty tissue (MFA±SDFA). Results and their discussion. Using the accumulated database, programmed in Excel for each of the patients, the basis of the data of direct anthropometry calculated: index of absolute fat mass (MFA) and endomorphic index (MFB), which allowed determining ontogenetic harmonious relation of fat mass components body, defined relative and absolute frequencies of this phenomenon. Analysis of these data revealed that the frequency of ontogenetic disharmony of fat component of body mass analyzed by ontogenetic periods ranged from 11,0±1,6 % to 30,0±3,0 %, averaging over all persons at 15,4±1,0 %. Among males the lowest frequency of disharmony body weight on his fat component found in the second period of childhood - is 8,4±1,8%, and the highest - 33,3±4,4 % in the first period of adulthood. Among females the highest frequency disharmony of body weight on his fat component found in the first period of adult age -26,7±4,1 %, whereas in previous ontogenetic periods, this figure has been relatively stable and not significantly different, depending on age. Based on the data, elaborated analytical and numerical models (polynomials) frequency of ontogenetic disharmony of body weight due to fat component, which allows the application to objectify identified patterns and, if necessary, calculate the frequency of ontogenetic are caused chopped disharmony of body weight in fat component by gender (means of traveling power-substitution instead of X - the number you ontogenetic period). Conclusions. On the basis of direct anthropometry the regularities of formation of human body fat at the stages of postnatal ontogenesis have been revealed, which become apparent by different rate of body mass disharmony due to its fat component, especially in comparative aspect of gender groups' ontogenesis. The findings of generalized development of aggregated anthropometric data define the areas of development of traditional methodology of anthropometry, valid advanced methodology, in particular; provides with estimation of ontogenetically disharmonic body build due to body mass fat component. The assessment of ontogenetic disharmony of body mass fat component is assigned to anatomy, topographic anatomy, and other clinical disciplines and can be applied to consideration of peculiarities of body build while assessing the body composition. The findings can explain the age differences as for the rate of initiation of functional disorders, prenosological, as well as nosologically defined pathological conditions as manifestation of general process of growth and development in postnatal ontogenesis.

91-93

Authors: Dosberdiyeva G.T.

In this article data on prevalence of stomatologic diseases in people of senile age are provided in some countries, and also relevance of carrying out epidemiological research of prevalence of various stomatologic pathology in elderly people in Kazakhstan is proved.

97-101

Authors: Sagimova R.Sh., Musabekova R.K., Eszhanova R.K., Umbetova L.Zh., Satiyeva Zh.Zh.

In the article the use of experience for stationary substituting technologies in organization of medical aid to children in conditions of out-patient-policlinic is analysed. Comparative description of efficiency of treatment of children is given with pneumonia in stationary at home and ambulatory with the visit of policlinic. Pneumonia can have severe course. Study of the clinical effectiveness in the stationary at home treatment with pneumonia in children a comprehensive survey of 36 children aged 3 years to 15 years were carried out. As a result of treatment patients who were treated with pneumonia were allowed to reduce the duration and severity of clinical and radiological signs, marked shortened hospital stay and prevented in-patient infection. These results indicate a high efficacy and safety in the treatment of respiratory pathology in children. Accessible and informative indicators of an estimation of work productivity of stationary at home in children with pneumonia are offered.

107-111

Authors: Stanbekov D.R.

Current world practice evidences that there is no uniform form of payment for work of medical workers. In spite of widespread implementation of various work remuneration systems in neighboring and other countries, the use of capitation standard rate is intended to encourage medical workers to provide the best care at the least cost.

115-117

Authors: Rahadilov E.M., Ospanova D.A.

Issues of quality of care neurosurgical patients and its effectiveness on the results of sociological research are presented in this article. According to the interviewed doctors the quality of care in the department in which they work depends on the material and technical base, personnel structure and personnel administration as well as important is the organizational and service level. Attitude of patients showed that the majority of patients are satisfied with the medical care. These factors are almost identical to the main sections of the accreditation program.

121-123

Authors: Shynterekova A.E.

Assessment of public satisfaction with the work of Shymkent ambulance station was carried out on the basis of a sociological survey of 60 respondents, in particular, the employees themselves stations. Reducing latency ambulance does not lead to public satisfaction at the low potential employee qualification station. Over 50 % of mobile teams of experts working at the station at least 5 years.