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Surveillance of multidrug resistant suppurative infection causing bacteria in hospitalized patients in an Indian tertiary care hospital
Authors: Nabakishore Nayak, Rajesh K. Lenka, Rabindra N. Padhy
Number of views: 421
Objective: To examine antibiograms of a cohort of suppurative bacteria isolated from woundswabs from hospitalized patients of all economic groups of a typical Indian teaching hospital.
Methods: In surveillance, antibiotic resistance patterns of 10 species of suppurative bacteria
isolated from wound-swabs over a period of 24 months were recorded. Those were subjected to
antibiotic sensitivity test, using 16 prescribed antibiotics of 5 different groups (3 aminoglycosides,
4 beta-lactams, 3 cephalosporins, 4 fluoroquinolones, and 2 stand-alone) in each 6-month
interval of the study period. Results: Of 1 156 samples collected, 819 samples yielded pathogenic
bacteria, of which, Staphylococcus aureus (S. aureus), Streptococcus pyogenes (S. pyogenes),
Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), Enterococcus faecalis (E. faecalis),
Klebsiella pneumoniae (K. pneumoniae), Acinetobacter baumannii (A. baumannii), Enterobacter
aerogenes (E. aerogenes), Proteus mirabilis (P. mirabilis) and Proteus vulgaris (P. vulgaris)
were isolated in the order of predominance. Isolated bacterial strains were floridly multidrug
resistant. Strains of E. faecalis and S. aureus were found resistant to vancomycin, one of the newly
introduced antibiotics. Conclusions: Of these S. aureus, particularly the methicillin resistant
strain predominates, followed by strains of S. pyogenes and P. aeruginosa that were in the higher
proportions of multidrug resistance.