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Imaging in the diagnosis of chronic pancreatitis
Authors: Vasile D. Balaban, Andrei M. Lungu, Dragoș Cuzino, Săndica Bucurică, Bogdan Macadon,Mihăiță Pătrășescu, Raluca S. Costache, Petruț Nuță, Constantin Ştefani, Florentina Ioniță-Radu, Mariana Jinga
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Chronic pancreatitis is characterised by progressive and irreversible damage of the
pancreatic parenchyma and ductal system, which leads to chronic pain, loss of endocrine and
exocrine functions. Clinically, pancreatic exocrine insufficiency becomes apparent only after 90% of
the parenchima has been lost. Despite the simple definition, diagnosing chronic pancreatitis
remains a challenge, especially for early stage disease. Because pancreatic function tests can be
normal until late stages and have significant limitations, there is an incresing interest in the role of
imaging techniques for the diagnosis of chronic pancreatitis. In this article we review the utility
and accuracy of different imaging methods in the diagnosis of chronic pancreatitis, focusing on the
role of advanced imaging (magnetic resonance imaging, endoscopic retrograde
cholangiopancreatography and endoscopic ultrasound).